Juvenile Macular Degeneration (JMD) Marketed and Pipeline Drugs Assessment, Clinical Trials and Competitive Landscape

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Published: August 04, 2023 Report Code: GDHC125CL-ST

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Juvenile Macular Degeneration (JMD) Marketed and Pipeline Drugs Overview

JMD, also called juvenile macular dystrophy, is a group of inherited eye disorders that affects children and young adults, disturbing their central vision. JMD is classified into three major types: Stargardt disease, X-linked retinoschisis (juvenile retinoschisis), and Best vitelliform macular dystrophy (Best’s disease). In the 16MM (Australia, Brazil, China, Canada, France, Germany, India, Italy, Japan, Mexico, Russia, South Africa, South Korea, Spain, UK, and the US), epidemiologists estimate there were around 555,113 diagnosed prevalent cases of JMD in 2023. As there are currently no approved treatment options available for JMD, a treatment algorithm has not yet been established for the disease. The condition is currently being managed by physicians with the help of a variety of low vision aids accompanied by adaptive training.

The Juvenile Macular Degeneration (JMD) marketed and pipeline drugs market research report includes an assessment of the disease epidemiology, leading marketed products with sales forecast, pricing and reimbursement, and late-to-mid-stage pipeline products with Phase Transition Success Rate (PTSR), and Likelihood of Approval (LoA) for Juvenile Macular Degeneration (JMD). The report also analyzes the clinical and commercial landscapes of JMD drugs, as well as an assessment of deals, future market catalysts, key market players, and the future competitive environment.

Key Mechanism of Action (Pipeline) ·       Transporter Activators

·       Receptor Agonists

·       Protein and Peptide Inhibitors

·       Receptor Activators

·       Enzyme Activators

·       Enzyme Inhibitors
Key Routes of Administration (Pipeline) ·       Injection

·       Oral

·       Topical
Key Molecule Type (Pipeline) ·       Biologic

·       Small Molecule

·       Oligonucleotide
Top Sponsors (Pipeline Drugs) ·       Stargazer Pharmaceuticals

·       Alkeus Pharmaceuticals Inc

·       Kubota Vision

·       Belite Bio

·       Alnylam Pharmaceuticals
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JMD Pipeline Drugs Market Segmentation by Mechanisms of Action

The key mechanisms of action for JMD pipeline drugs are transporter activators, receptor agonists, protein and peptide inhibitors, receptor activators, enzyme activators, and enzyme inhibitors. In 2023, most of the pipeline drugs in the JMD landscape are transporter activators followed by receptor agonists and protein and peptide inhibitors in terms of mechanism of action.

JMD Pipeline Drugs Market Analysis by Mechanisms of Action, 2023 (%)

JMD Pipeline Drugs Market Analysis by Mechanisms of Action, 2023 (%)

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JMD Pipeline Drugs Market Segmentation by Routes of Administration

The key routes of administration for JMD pipeline drugs are injection, oral, and topical. In 2023, most of the pipeline drugs in the JMD landscape are administered using injections followed by oral.

JMD Pipeline Drugs Market Analysis by Routes of Administration, 2023 (%)

JMD Pipeline Drugs Market Analysis by Routes of Administration, 2023 (%)

For more RoA insights into the JMD pipeline drugs market, download a free report sample

JMD Pipeline Drugs Market Segmentation by Molecule Type

The key molecule types for the JMD pipeline drugs market are small molecule, biologic, and oligonucleotide. In 2023, most of the pipeline drugs in the JMD drug development landscape are biologics followed by small molecule.

JMD Pipeline Drugs Market Analysis by Molecule Types, 2023 (%)

JMD Pipeline Drugs Market Analysis by Molecule Types, 2023 (%)

For more molecule type insights into the JMD pipeline drugs market, download a free report sample

Top Sponsors in the JMD Marketed and Pipeline Drugs Market

Some of the top sponsors in the JMD marketed and pipeline drugs market are Stargazer Pharmaceuticals, Alkeus Pharmaceuticals Inc, Biophytis SA, Kubota Vision Inc, Belite Bio Inc, Lin Bioscience Inc, and Alnylam Pharmaceuticals among others. In 2023, Stargazer Pharmaceuticals dominated the JMD marketed and pipeline drugs market conducting the highest number of trials.

JMD Marketed and Pipeline Drugs Market Analysis by Sponsors, 2023 (%)

JMD Marketed and Pipeline Drugs Market Analysis by Sponsors, 2023 (%)

For more sponsor insights into the JMD marketed and pipeline drugs Market, download a free report sample

JMD Marketed and Pipeline Drugs Segments

JMD Pipeline Drugs Mechanisms of Action Outlook (Number of Drugs, 2023)

  • Transporter Activator
  • Receptor Agonist
  • Protein and Peptide Inhibitor
  • Receptor Activator
  • Enzyme Activator
  • Enzyme Inhibitor

JMD Pipeline Drugs Routes of Administration Outlook (Number of Drugs, 2023)

  • Oral
  • Injection
  • Topical

JMD Pipeline Drugs Molecule Types Outlook (Number of Drugs, 2023)

  • Small Molecule
  • Biologic
  • Oligonucleotide

Scope

GlobalData’s JMD: Competitive Landscape combines data from the Pharma Intelligence Center with in-house analyst expertise to provide a competitive assessment of the disease marketplace.

Components of the report include –

  • Disease Landscape

  • Disease Overview

  • Epidemiology Overview

  • Treatment Overview

  • Marketed Products Assessment

  • Breakdown by Mechanism of Action, Route of Administration

  • Product Profiles with Sales Forecast

  • Pricing and Reimbursement Assessment

  • Annual Therapy Cost

  • Time to Pricing and Time to Reimbursement

  • Pipeline Assessment

  • Breakdown by Development Stage, Mechanism of Action, Molecule Type, Route of Administration

  • Product Profiles with Sales Forecast

  • Late-to-mid-stage Pipeline Drugs

  • Phase Transition Success Rate and Likelihood of Approval

  • Clinical Trials Assessment

  • Breakdown of Trials by Phase, Status, Virtual Components, Sponsors, Geography, and Endpoint Status

  • Enrolment Analytics, Site Analytics, Feasibility Analysis

  • Deals Landscape

  • Mergers, Acquisitions, and Strategic Alliances by Region

  • Overview of Recent Deals

  • Commercial Assessment

  • Key Market Players

  • Future Market Catalysts

Reasons to Buy

  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.

  • Develop business strategies by understanding the trends shaping and driving the JMD market.

  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global JMD market in the future.

  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.

  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.

  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments, and strategic partnerships.

Table of Contents

1 Preface

1.1 Contents

1.2 Report Scope

1.3 List of Tables and Figures

1.4 Abbreviations

2 Key Findings

3 Disease Landscape

3.1 Disease Overview

3.2 Epidemiology Overview

3.3 Treatment Overview

4 Marketed Drugs Assessment

5 Pricing and Reimbursement Assessment

6 Pipeline Drugs Assessment

6.1 Phase III Pipeline Drugs

6.2 Overview by Development Stage

6.3 Overview by Molecule Type

6.4 Overview by Mechanism of Action

6.5 Overview by Route of Administration

6.6 Drug Specific Phase Transition Success Rate (PTSR) and Likelihood of Approval (LoA)

6.7 Therapy Area and Indication-specific PTSR and LoA

7 Clinical Trials Assessment

7.1 Historical Overview

7.2 Overview by Phase

7.3 Overview by Status

7.4 Overview by Phase for Ongoing and Planned Trials

7.5 Trials with Virtual Components

7.6 Geographic Overview

7.7 Single-Country and Multinational Trials by Region

7.8 Top 20 Sponsors with Breakdown by Phase

7.9 Top 20 Sponsors with Breakdown by Status

7.10 Overview by Endpoint Status

7.11 Overview by Race and Ethnicity

7.12 Enrollment Data

7.13 Top 20 countries for Trial Sites

7.14 Top 20 Sites Globally

7.15 Feasibility Analysis – Geographic Overview

7.16 Feasibility Analysis – Benchmark Models

8 Deals Landscape

8.1 Mergers, Acquisitions, and Strategic Alliances by Region

8.2 Recent Mergers, Acquisitions, and Strategic Alliances

9 Commercial Assessment

9.1 Key Market Players

10 Future Market Catalysts

11 Appendix

11.1 Methodology

11.2 Methodology – Sales Forecast

11.3 Methodology – Pricing and Reimbursement

11.4 Methodology – PTSR and LoA Analysis

11.5 About the Authors

11.6 Contact Us

11.7 Disclaimer

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