Table 1: Knee Reconstruction – Pipeline Products by Stage of Development 12
Table 2: Knee Reconstruction – Pipeline Products by Segment 13
Table 3: Knee Reconstruction – Pipeline Products by Territory 14
Table 4: Knee Reconstruction – Pipeline Products by Regulatory Path 15
Table 5: Knee Reconstruction – Pipeline Products by Estimated Approval Date 16
Table 6: Knee Reconstruction – Ongoing Clinical Trials 17
Table 7: Knee Reconstruction Companies – Pipeline Products by Stage of Development 18
Table 8: Knee Reconstruction – Pipeline Products by Stage of Development 20
Table 9: 4WEB Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 22
Table 10: Truss Implant – Knee Procedures – Product Status 22
Table 11: Truss Implant – Knee Procedures – Product Description 22
Table 12: Active Implants LLC Pipeline Products & Ongoing Clinical Trials Overview 23
Table 13: NUsurface Meniscus Implant – Product Status 23
Table 14: NUsurface Meniscus Implant – Product Description 23
Table 15: Active Implants LLC – Ongoing Clinical Trials Overview 24
Table 16: NUsurface Meniscus Implant – A Long-term Non-interventional Registry Study to Assess the Effectiveness and Safety of the NUsurface Meniscus Implant 25
Table 17: NUsurface Meniscus Implant – The SUN Clinical Trial (Safety Utilizing NUsurface Meniscus Implant). A Multi-center, Single-arm, Prospective, Open-label, Non-randomized, Observational Clinical Study 25
Table 18: Amplitude SAS Pipeline Products & Ongoing Clinical Trials Overview 26
Table 19: ACLip – Product Status 26
Table 20: ACLip – Product Description 26
Table 21: Artimplant AB (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 27
Table 22: Knee Resurfacing Implant – Product Status 27
Table 23: Knee Resurfacing Implant – Product Description 27
Table 24: Aspect Biosystems Ltd Pipeline Products & Ongoing Clinical Trials Overview 28
Table 25: Bioprinted Knee Meniscus Tissue – Product Status 28
Table 26: Bioprinted Knee Meniscus Tissue – Product Description 28
Table 27: ATRO Medical BV Pipeline Products & Ongoing Clinical Trials Overview 29
Table 28: Trammpolin – Product Status 29
Table 29: Trammpolin – Product Description 29
Table 30: ATRO Medical BV – Ongoing Clinical Trials Overview 30
Table 31: Trammpolin – Treatment of Medial Knee Joint Pain with the Trammpolin Meniscus Prosthesis 31
Table 32: B. Braun Melsungen AG Pipeline Products & Ongoing Clinical Trials Overview 32
Table 33: Biological Knee Regeneration Device – Product Status 32
Table 34: Biological Knee Regeneration Device – Product Description 32
Table 35: Binghampton University Pipeline Products & Ongoing Clinical Trials Overview 33
Table 36: Smart Knee Implant – Product Status 33
Table 37: Smart Knee Implant – Product Description 33
Table 38: BioPoly RS LLC Pipeline Products & Ongoing Clinical Trials Overview 34
Table 39: BioPoly RS Partial Resurfacing Femoral System – Product Status 34
Table 40: BioPoly RS Partial Resurfacing Femoral System – Product Description 34
Table 41: Biopoly RS Partial Resurfacing Knee – Product Status 35
Table 42: Biopoly RS Partial Resurfacing Knee – Product Description 35
Table 43: BioPoly RS Partial Resurfacing Patella – Product Status 35
Table 44: BioPoly RS Partial Resurfacing Patella – Product Description 36
Table 45: BioPoly RS Partial Resurfacing Trochlea System – Product Status 36
Table 46: BioPoly RS Partial Resurfacing Trochlea System – Product Description 36
Table 47: BioPoly RS LLC – Ongoing Clinical Trials Overview 37
Table 48: BioPoly RS Partial Resurfacing Femoral System – Multi-center, Open Label, Prospective, Consecutive Series Registry Database of BioPoly RS Partial Resurfacing Knee Implant 38
Table 49: BioPoly RS Partial Resurfacing Patella – Open Label, Prospective, Consecutive Series Registry Database of Biopoly RS Partial Resurfacing Patella Implant 39
Table 50: Bonovo Orthopedics Inc Pipeline Products & Ongoing Clinical Trials Overview 40
Table 51: JMM Total Knee System – Product Status 40
Table 52: JMM Total Knee System – Product Description 40
Table 53: CeramTec GmbH Pipeline Products & Ongoing Clinical Trials Overview 41
Table 54: BIOLOX Delta – Knee – Product Status 41
Table 55: BIOLOX Delta – Knee – Product Description 41
Table 56: Clemson University Pipeline Products & Ongoing Clinical Trials Overview 42
Table 57: Engage Knee System – Product Status 42
Table 58: Engage Knee System – Product Description 42
Table 59: ConforMIS Inc Pipeline Products & Ongoing Clinical Trials Overview 43
Table 60: ASC Cementless Knee Replacement System – Product Status 43
Table 61: ASC Cementless Knee Replacement System – Product Description 43
Table 62: ASC Knee Replacement System – Product Status 44
Table 63: ASC Knee Replacement System – Product Description 44
Table 64: Corin Group Ltd Pipeline Products & Ongoing Clinical Trials Overview 45
Table 65: IL-Knee – Product Status 45
Table 66: IL-Knee – Product Description 45
Table 67: IL-Knee 1 – Product Status 46
Table 68: IL-Knee 1 – Product Description 46
Table 69: IL-Knee 2 – Product Status 46
Table 70: IL-Knee 2 – Product Description 46
Table 71: DiFusion Technologies Inc Pipeline Products & Ongoing Clinical Trials Overview 47
Table 72: ACL Repair Screw – Product Status 47
Table 73: ACL Repair Screw – Product Description 47
Table 74: Ecole de technologie superieure Pipeline Products & Ongoing Clinical Trials Overview 48
Table 75: Knee Resurfacing Implant – Product Status 48
Table 76: Knee Resurfacing Implant – Product Description 48
Table 77: Elite Surgical Supplies (Pty) Ltd Pipeline Products & Ongoing Clinical Trials Overview 49
Table 78: UNIQ PARTIAL KNEE – Product Status 49
Table 79: UNIQ PARTIAL KNEE – Product Description 49
Table 80: Episurf Medical AB Pipeline Products & Ongoing Clinical Trials Overview 50
Table 81: Episealer Condyle Solo – Product Status 50
Table 82: Episealer Condyle Solo – Product Description 51
Table 83: Episealer Trochlea Solo – Product Status 51
Table 84: Episealer Trochlea Solo – Product Description 51
Table 85: Episurf Medical AB – Ongoing Clinical Trials Overview 52
Table 86: Episealer Condyle Solo – A Prospective, Randomized, Controlled, Multi-center Study to Evaluate the Safety and Effectiveness of the Episealer Knee System Compared to Microfracture for the Treatment of Focal Femoral Knee Chondral or Osteochondral Lesions 53
Table 87: Episealer Condyle Solo – Efficacy of Focal Individualised Mini-metal Implant in Treatment of Focal Cartilage Lesions in the Knee 53
Table 88: Episealer Condyle Solo – X-ray Fluoroscopic Analysis of Knee Joint Kinematic in Open and Closed Chain Activities in Patients with Episealer Knee Implants 53
Table 89: Episealer Trochlea Solo – A Prospective, Randomized, Controlled, Multi-center Study to Evaluate the Safety and Effectiveness of the Episealer Knee System Compared to Microfracture for the Treatment of Focal Femoral Knee Chondral or Osteochondral Lesions 54
Table 90: Episealer Trochlea Solo – Efficacy of Focal Individualised Mini-metal Implant in Treatment of Focal Cartilage Lesions in the Knee 54
Table 91: Episealer Trochlea Solo – Long-term Prospective Interventional Clinical Trial of an MRI Based Patient Specific Focal Knee Resurfacing Implant – Episealer 2 Study 54
Table 92: Episealer Trochlea Solo – X-ray Fluoroscopic Analysis of Knee Joint Kinematic in Open and Closed Chain Activities in Patients with Episealer Knee Implants 55
Table 93: Exactech Inc Pipeline Products & Ongoing Clinical Trials Overview 56
Table 94: Adv. Ligament Balancing System – Product Status 56
Table 95: Adv. Ligament Balancing System – Product Description 56
Table 96: Exactech GPS CC System – Product Status 57
Table 97: Exactech GPS CC System – Product Description 57
Table 98: Exactech GPS Uni System – Product Status 57
Table 99: Exactech GPS Uni System – Product Description 58
Table 100: One Logic Patella System – Product Status 58
Table 101: One Logic Patella System – Product Description 58
Table 102: Optetrak Logic RBK System – Product Status 59
Table 103: Optetrak Logic RBK System – Product Description 59
Table 104: Optetrak Logic Unicondylar System – Product Status 59
Table 105: Optetrak Logic Unicondylar System – Product Description 60
Table 106: EZ ORTHOPEDICS ISRAEL Pipeline Products & Ongoing Clinical Trials Overview 61
Table 107: EZ KneeSpan – Product Status 61
Table 108: EZ KneeSpan – Product Description 61
Table 109: ForCast Orthopedics Inc Pipeline Products & Ongoing Clinical Trials Overview 62
Table 110: Antibiotic Dispensing Spacer – Product Status 62
Table 111: Antibiotic Dispensing Spacer – Product Description 62
Table 112: Fuse Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 63
Table 113: Revision Knee System – Product Status 63
Table 114: Revision Knee System – Product Description 63
Table 115: Genovel Orthopedics Inc Pipeline Products & Ongoing Clinical Trials Overview 64
Table 116: Anatomical Knee – Product Status 64
Table 117: Anatomical Knee – Product Description 64
Table 118: Mini-Knee – Product Status 65
Table 119: Mini-Knee – Product Description 65
Table 120: Georgia Institute of Technology Pipeline Products & Ongoing Clinical Trials Overview 66
Table 121: Artificial Meniscus Implant – Product Status 66
Table 122: Artificial Meniscus Implant – Product Description 66
Table 123: Hospital for Special Surgery Pipeline Products & Ongoing Clinical Trials Overview 67
Table 124: Locking Mechanism Device For Tibial Component – Product Status 67
Table 125: Locking Mechanism Device For Tibial Component – Product Description 67
Table 126: Revision Knee System – Product Status 68
Table 127: Revision Knee System – Product Description 68
Table 128: Indian Institute of Technology Bombay Pipeline Products & Ongoing Clinical Trials Overview 69
Table 129: Modular Knee Joint Implant – Product Status 69
Table 130: Modular Knee Joint Implant – Product Description 69
Table 131: Invibio Knee Ltd Pipeline Products & Ongoing Clinical Trials Overview 70
Table 132: PEEK-OPTIMA Femoral Knee Replacement Device – Product Status 70
Table 133: PEEK-OPTIMA Femoral Knee Replacement Device – Product Description 70
Table 134: Invibio Knee Ltd – Ongoing Clinical Trials Overview 71
Table 135: PEEK-OPTIMA Femoral Knee Replacement Device – A Multi-center Clinical Investigation to Evaluate the Safety and Performance of the Freedom Total Knee System with the PEEK-OPTIMA Femoral Component 72
Table 136: Kinamed Inc Pipeline Products & Ongoing Clinical Trials Overview 73
Table 137: GEM – Total Knee System – Product Status 73
Table 138: GEM – Total Knee System – Product Description 73
Table 139: Materialise NV Pipeline Products & Ongoing Clinical Trials Overview 74
Table 140: X-ray Knee Guide System – Product Status 74
Table 141: X-ray Knee Guide System – Product Description 74
Table 142: Materials Mines Paris Tech Center Pipeline Products & Ongoing Clinical Trials Overview 75
Table 143: LIGAGEL – Product Status 75
Table 144: LIGAGEL – Product Description 75
Table 145: Medacta Group SA Pipeline Products & Ongoing Clinical Trials Overview 76
Table 146: Medacta TiNbN Coated Partial Knee System – Product Status 76
Table 147: Medacta TiNbN Coated Partial Knee System – Product Description 76
Table 148: MOTO PFJ System – Product Status 77
Table 149: MOTO PFJ System – Product Description 77
Table 150: Miach Orthopaedics Inc Pipeline Products & Ongoing Clinical Trials Overview 78
Table 151: BEAR Implant – Product Status 78
Table 152: BEAR Implant – Product Description 78
Table 153: Miach Orthopaedics Inc – Ongoing Clinical Trials Overview 79
Table 154: BEAR Implant – A Prospective Cohort Clinical Trial Evaluating Age as a Risk Factor for Poor Outcomes of Bridge-enhanced ACL Repair: BEAR 80
Table 155: BEAR Implant – A Prospective, Randomized, Controlled, Clinical Trial Evaluating the Non-inferiority of Bridge-enhanced Anterior Cruciate Ligament Repair (BEAR) to Anterior Cruciate Ligament Reconstruction with an Autologous Tendon Graft (ACLR) 80
Table 156: BEAR Implant – A Two Arm Non-inferiority Randomized Clinical Trial Comparing ACL Repair with BEAR Device Vs. Autograft Patellar Tendon ACL Reconstruction: BEAR-MOON 80
Table 157: MicroPort Orthopedics Inc Pipeline Products & Ongoing Clinical Trials Overview 81
Table 158: Evolution NitrX Medial-Pivot Knee System – Product Status 81
Table 159: Evolution NitrX Medial-Pivot Knee System – Product Description 82
Table 160: Nano Interface Technology LLC (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 83
Table 161: Knee Implant – Product Status 83
Table 162: Knee Implant – Product Description 83
Table 163: National Research Tomsk Polytechnic University Pipeline Products & Ongoing Clinical Trials Overview 84
Table 164: Tibia Implant – Product Status 84
Table 165: Tibia Implant – Product Description 84
Table 166: NovoPedics, Inc. Pipeline Products & Ongoing Clinical Trials Overview 85
Table 167: Meniscofix – Product Status 85
Table 168: Meniscofix – Product Description 85
Table 169: NuVasive Inc Pipeline Products & Ongoing Clinical Trials Overview 86
Table 170: PRECICE OPTY-LINE System – Product Status 86
Table 171: PRECICE OPTY-LINE System – Product Description 86
Table 172: Ohio State University Pipeline Products & Ongoing Clinical Trials Overview 87
Table 173: Joint Stability Measurement Device – Product Status 87
Table 174: Joint Stability Measurement Device – Product Description 87
Table 175: Okani Medical Technology Pipeline Products & Ongoing Clinical Trials Overview 88
Table 176: ORGKnee Implant – Product Status 88
Table 177: ORGKnee Implant – Product Description 88
Table 178: OrthoGrid Systems Pipeline Products & Ongoing Clinical Trials Overview 89
Table 179: KneeFXGrid – Product Status 89
Table 180: KneeFXGrid – Product Description 89
Table 181: Orthonika Ltd Pipeline Products & Ongoing Clinical Trials Overview 90
Table 182: MenisciKnit – Product Status 90
Table 183: MenisciKnit – Product Description 90
Table 184: Resultados y Calidad del Sistema Sanitario Publico de Andalucia Pipeline Products & Ongoing Clinical Trials Overview 91
Table 185: Knee Replacement Implant – Product Status 91
Table 186: Knee Replacement Implant – Product Description 91
Table 187: Secondary Knee Prosthesis – Product Status 92
Table 188: Secondary Knee Prosthesis – Product Description 92
Table 189: RIH Orthopaedic Foundation Inc Pipeline Products & Ongoing Clinical Trials Overview 93
Table 190: TruTarget System – Product Status 93
Table 191: TruTarget System – Product Description 93
Table 192: Sanatmetal Ltd. Pipeline Products & Ongoing Clinical Trials Overview 94
Table 193: Sanatmetal's Knee Joint Replacement System – Product Status 94
Table 194: Sanatmetal's Knee Joint Replacement System – Product Description 94
Table 195: Sensortech Corp Pipeline Products & Ongoing Clinical Trials Overview 95
Table 196: Force Check Knee Replacement Smart Insert – Product Status 95
Table 197: Force Check Knee Replacement Smart Insert – Product Description 95
Table 198: SINTX Technologies Inc Pipeline Products & Ongoing Clinical Trials Overview 96
Table 199: Total Knee Implant – Product Status 96
Table 200: Total Knee Implant – Product Description 96
Table 201: Smith & Nephew Plc Pipeline Products & Ongoing Clinical Trials Overview 97
Table 202: LEGION RH Hinge – Product Status 97
Table 203: LEGION RH Hinge – Product Description 97
Table 204: Robotics-Assisted Revision Knee System – Product Status 98
Table 205: Robotics-Assisted Revision Knee System – Product Description 98
Table 206: Stellenbosch University Pipeline Products & Ongoing Clinical Trials Overview 99
Table 207: uMove – Product Status 99
Table 208: uMove – Product Description 99
Table 209: Stevens Institute of Technology Pipeline Products & Ongoing Clinical Trials Overview 100
Table 210: OrthoInsight – Product Status 100
Table 211: OrthoInsight – Product Description 100
Table 212: University of Florida Pipeline Products & Ongoing Clinical Trials Overview 101
Table 213: Spacer Block With Sensor – Product Status 101
Table 214: Spacer Block With Sensor – Product Description 101
