1 Table of Contents
1 Table of Contents 2
1.1 List of Tables 6
1.2 List of Figures 7
2 Introduction 9
2.1 What Is This Report About? 9
2.2 Cardiac Rhythm Management Devices Segmentation 9
2.3 Definitions of Markets Covered in the Report 10
3 Cardiac Rhythm Management Devices Market, North America 12
3.1 Cardiac Rhythm Management Devices Market, North America, Revenue ($m), 2015-2025 12
3.2 Cardiac Rhythm Management Devices Market, North America, Revenue ($m), 2015-2025 14
3.3 Cardiac Rhythm Management Devices Market, North America, Volume (Units), 2015-2025 17
3.4 Cardiac Rhythm Management Devices Market, North America, Volume (Units), 2015-2025 19
3.5 Cardiac Rhythm Management Devices Market, North America, Company Share by Revenue ($m), 2017 22
4 Cardiac Rhythm Management Devices Market, Canada 24
4.1 Cardiac Rhythm Management Devices Market, Canada, Revenue ($m), 2015-2025 24
4.1.1 Cardiac Resynchronisation Therapy (CRT) Market, Canada, Revenue ($m), by Segment, 2015-2025 27
4.1.2 Implantable Cardioverter Defibrillators (ICD) Market, Canada, Revenue ($m), by Segment, 2015-2025 30
4.1.3 Pacemakers Market, Canada, Revenue ($m), by Segment, 2015-2025 33
4.2 Cardiac Rhythm Management Devices Market, Canada, Volume (Units), 2015-2025 36
4.2.1 Cardiac Resynchronisation Therapy (CRT) Market, Canada, Volume (Units), by Segment, 2015-2025 39
4.2.2 Implantable Cardioverter Defibrillators (ICD) Market, Canada, Volume (Units), by Segment, 2015-2025 42
4.2.3 Pacemakers Market, Canada, Volume (Units), by Segment, 2015-2025 45
4.3 Cardiac Rhythm Management Devices Market, Canada, Average Price ($), 2015-2025 48
4.4 Cardiac Rhythm Management Devices Market, Canada, Distribution Share by Revenue ($m), 2017 50
4.5 Cardiac Rhythm Management Devices Market, Canada, Company Share by Revenue ($m), 2017 51
5 Cardiac Rhythm Management Devices Market, Mexico 53
5.1 Cardiac Rhythm Management Devices Market, Mexico, Revenue ($m), 2015-2025 53
5.1.1 Cardiac Resynchronisation Therapy (CRT) Market, Mexico, Revenue ($m), by Segment, 2015-2025 56
5.1.2 Implantable Cardioverter Defibrillators (ICD) Market, Mexico, Revenue ($m), by Segment, 2015-2025 58
5.1.3 Pacemakers Market, Mexico, Revenue ($m), by Segment, 2015-2025 60
5.2 Cardiac Rhythm Management Devices Market, Mexico, Volume (Units), 2015-2025 62
5.2.1 Cardiac Resynchronisation Therapy (CRT) Market, Mexico, Volume (Units), by Segment, 2015-2025 65
5.2.2 Implantable Cardioverter Defibrillators (ICD) Market, Mexico, Volume (Units), by Segment, 2015-2025 67
5.2.3 Pacemakers Market, Mexico, Volume (Units), by Segment, 2015-2025 69
5.3 Cardiac Rhythm Management Devices Market, Mexico, Average Price ($), 2015-2025 71
5.4 Cardiac Rhythm Management Devices Market, Mexico, Distribution Share by Revenue ($m), 2017 73
5.5 Cardiac Rhythm Management Devices Market, Mexico, Company Share by Revenue ($m), 2017 74
6 Cardiac Rhythm Management Devices Market, United States 76
6.1 Cardiac Rhythm Management Devices Market, United States, Revenue ($m), 2015-2025 76
6.1.1 Cardiac Resynchronisation Therapy (CRT) Market, United States, Revenue ($m), by Segment, 2015-2025 79
6.1.2 Implantable Cardioverter Defibrillators (ICD) Market, United States, Revenue ($m), by Segment, 2015-2025 81
6.1.3 Pacemakers Market, United States, Revenue ($m), by Segment, 2015-2025 83
6.2 Cardiac Rhythm Management Devices Market, United States, Volume (Units), 2015-2025 85
6.2.1 Cardiac Resynchronisation Therapy (CRT) Market, United States, Volume (Units), by Segment, 2015-2025 88
6.2.2 Implantable Cardioverter Defibrillators (ICD) Market, United States, Volume (Units), by Segment, 2015-2025 90
6.2.3 Pacemakers Market, United States, Volume (Units), by Segment, 2015-2025 92
6.3 Cardiac Rhythm Management Devices Market, United States, Average Price ($) , 2015-2025 94
6.4 Cardiac Rhythm Management Devices Market, United States, Distribution Share by Revenue ($m), 2017 96
6.5 Cardiac Rhythm Management Devices Market, United States, Company Share by Revenue ($m), 2017 97
7 Overview of Key Companies in North America Cardiac Rhythm Management Devices Market 99
7.1 Medtronic Plc 99
7.1.1 Company Overview 99
7.2 Abbott Laboratories 99
7.2.1 Company Overview 99
7.3 Biotronik AG 99
7.3.1 Company Overview 99
7.4 Boston Scientific Corp 99
7.4.1 Company Overview 99
8 Cardiac Rhythm Management Devices Market Pipeline Products 100
9 Recent Developments 102
9.1 Corporate Communications 102
9.1.1 Apr 15, 2018: Genentech to Present Phase Ib/II Study Results of RG6206 102
9.1.2 Apr 10, 2018: iRhythm Technologies Appoints UCLA and Cedars-Sinai Professor C. Noel Bairey Merz, M.D. to its Board of Directors 102
9.1.3 Mar 13, 2018: Orthofix Announces Appointment of John Sicard to Board of Directors 103
9.1.4 Feb 13, 2018: Proteus Digital Health Appoints Joseph Swedish As Board Director 103
9.1.5 Jan 10, 2018: Ventripoint Appoints Head of Sales for North America 103
9.1.6 Dec 19, 2017: Ventripoint Diagnostics Provides Corporate Update 104
9.1.7 Nov 20, 2017: Follicum applies for the start of a Phase II study at the German Medicines Agency 104
9.1.8 Oct 11, 2017: New Data Shows That for Some Patients, Deep Brain Stimulation May Address Chronic Depression 105
9.1.9 Oct 04, 2017: Boston Scientific Appoints Desiree Ralls-Morrison General Counsel and Corporate Secretary 106
9.1.10 Sep 05, 2017: Former U. S. Surgeon General Dr. Regina Benjamin Joins the Board of Proteus Digital Health 107
9.1.11 Aug 23, 2017: Senior Novartis Executive Joins Proteus Digital Health as Chief Financial Officer 107
9.1.12 Jul 20, 2017: A Third Highly Successful Ultrasound Executive joins Ventripoint 108
9.1.13 Jun 21, 2017: Highly Successful Global Industry Sales & Marketing Executives Hired by Ventripoint 108
9.1.14 Jun 14, 2017: Spectranetics Announces Election of New Chairperson of the Board of Directors 109
9.2 Financial Announcements 109
9.2.1 Apr 25, 2018: Boston Scientific Announces Results For First Quarter 2018 109
9.2.2 Apr 16, 2018: USRM Reports 2017 Financial Results 111
9.2.3 Mar 28, 2018: MicroPort Scientific Announces 2017 Annual Results 112
9.2.4 Mar 06, 2018: Stereotaxis Reports 2017 Fourth Quarter And Full Year Financial Results 113
9.2.5 Feb 26, 2018: Orthofix International Reports Fourth Quarter And Fiscal 2017 Financial Results 115
9.2.6 Feb 08, 2018: Surmodics Reports First Quarter Fiscal 2018 Results, Updates Fiscal 2018 Guidance 116
9.2.7 Feb 01, 2018: Boston Scientific Announces Results for Fourth Quarter and Full Year 2017 116
9.2.8 Jan 23, 2018: Glytec's Software Yields Superior Patient Outcomes According to Four New Studies in Journal of Diabetes Science and Technology 118
9.2.9 Jan 09, 2018: Boston Scientific Announces Preliminary Unaudited Sales For The Fourth Quarter And Full Year Ended December 31, 2017 119
9.2.10 Jan 09, 2018: Orthofix Announces Preliminary 2017 Fourth Quarter and Full Year Net Sales Results 120
9.2.11 Jan 08, 2018: Stereotaxis Reports Preliminary Fourth Quarter 2017 Revenue Results 121
9.2.12 Dec 12, 2017: Cyclacel Announces Presentation of Results From Phase 3 Seamless Study at Ash Annual Meeting 121
9.2.13 Nov 09, 2017: Stereotaxis Reports Third Quarter 2017 Financial Results 122
9.2.14 Nov 08, 2017: Surmodics Reports Fourth Quarter Fiscal 2017 Results and Provides Fiscal 2018 Guidance 123
9.2.15 Nov 01, 2017: iRhythm Technologies Announces Third Quarter 2017 Financial Results And Raises Guidance For Full Year 2017 124
9.2.16 Oct 30, 2017: Orthofix International Reports Third Quarter 2017 Financial Results 125
9.2.17 Oct 26, 2017: Boston Scientific Announces Results For Third Quarter 2017 125
9.2.18 Oct 25, 2017: Bard Announces Third Quarter Results 126
9.2.19 Sep 26, 2017: Psychemedics Announces Addition of FDA-Cleared Benzodiazepines Hair Test 128
9.2.20 Sep 26, 2017: DFB Soria Gives Update on Enrollment in Phase 2 Clinical Trial of SOR007 (Nanoparticle Paclitaxel) Ointment for Actinic Keratosis (AK) 130
9.2.21 Aug 29, 2017: Medovex Receives Regulatory Approval from Australia's Therapeutic Goods Administration for its DenerveX System 131
9.2.22 Aug 15, 2017: CareRay Exhibits At FIME 2017 133
9.2.23 Aug 10, 2017: Stereotaxis Reports Second Quarter 2017 Financial Results 134
9.2.24 Aug 09, 2017: U.S. Stem Cell Reports Most Successful Financial Performance in the Company's History 134
9.2.25 Aug 07, 2017: Orthofix International Reports Second Quarter 2017 Financial Results 135
9.2.26 Aug 03, 2017: Surmodics Reports Third Quarter Fiscal 2017 Results and Updates Fiscal 2017 Guidance 136
9.2.27 Aug 03, 2017: Spectranetics Reports Second Quarter 2017 Revenue of $74.7 million 136
9.2.28 Aug 02, 2017: iRhythm Technologies Announces Second Quarter 2017 Financial Results 136
9.2.29 Jul 27, 2017: Boston Scientific Announces Results for Second Quarter 2017 137
9.2.30 Jun 21, 2017: Tolero Pharmaceuticals to Expand Enrollment of Phase II Study of Alvocidib in MCL-1-Dependent AML into Europe 139
9.2.31 May 08, 2017: Stereotaxis Reports 2017 First Quarter Financial Results 139
9.2.32 Apr 27, 2017: Boston Scientific Announces Results For First Quarter 2017 140
9.2.33 Apr 27, 2017: Surmodics Reports Second Quarter Fiscal 2017 Results, Updates Fiscal 2017 Financial Guidance 141
9.2.34 Apr 27, 2017: Spectranetics Reports First Quarter 2017 Revenue of $69.7 million 142
9.3 Legal And Regulatory 142
9.3.1 Aug 28, 2017: FDA warns US Stem Cell Clinic of significant deviations 142
9.3.2 Aug 03, 2017: Zoll Announces Jury Verdict in Zoll/Philips Patent Dispute 143
9.3.3 May 31, 2017: AngioDynamics Lawsuit Alleges C.R. Bard is Violating Antitrust Laws, Harming Competition and Limiting Access 143
9.4 Other Significant Developments 144
9.4.1 Feb 06, 2018: USRM Seeing Explosive Increase in Demand for Stem Cell Therapy 144
9.4.2 Aug 28, 2017: U.S. Stem Cell Clinic Acknowledges Warning Letter By The FDA and Responds 144
9.4.3 Jun 27, 2017: Boston Scientific Outlines Strategy for Sustained Growth at 2017 Investor Day 145
9.4.4 Jun 01, 2017: Nexus Pharmaceuticals Receives FDA Approval for Sodium Nitroprusside Injection 146
9.5 Product News 147
9.5.1 Nov 27, 2017: Ventripoint Invents a New Way to Track Ultrasound Probes That Will Speed up Exams 147
9.6 Strategy And Business Planning 147
9.6.1 Feb 07, 2018: Caisson Interventional Expanding in Maple Grove 147
9.6.2 Dec 11, 2017: Anthera Pharmaceuticals Announces Positive Outcome of Interim Futility Analysis in the Phase 3 RESULT Clinical Study of Sollpura 148
10 Appendix 149
10.1 Research Methodology 150
10.1.1 Coverage 150
10.1.2 Secondary Research 150
10.1.3 Primary Research 151
10.1.4 Market Modeling and Forecasting 152
10.1.5 Company Share Analysis 153
10.1.6 Distribution Share Analysis 154
10.1.7 Benchmarking 154
10.2 GlobalData Consulting 154
10.3 Contact Us 155
10.4 Disclaimer 155