1 Table of Contents
1.1 List of Tables
1.2 List of Figures
2 Introduction
2.1 What Is This Report About?
2.2 Orthobiologics Market Segmentation
2.3 Definitions of Markets Covered in the Report
3 Orthobiologics Market, North America
3.1 Orthobiologics Market, North America, Revenue ($m), 2018-2033
3.2 Orthobiologics Market, North America, Revenue ($m), 2018-2033
3.3 Orthobiologics Market, North America, Volume (Units), 2018-2033
3.4 Orthobiologics Market, North America, Volume (Units), 2018-2033
3.5 Orthobiologics Market, North America, Company Share by Revenue ($m), 2025
4 Orthobiologics Market, Canada
4.1 Orthobiologics Market, Canada, Revenue ($m), 2018-2033
4.1.1 Bone Grafts and Substitutes Market, Canada, Revenue ($m), by Segment, 2018-2033
4.1.2 Bone Growth Stimulators Market, Canada, Revenue ($m), by Segment, 2018-2033
4.1.3 Cartilage Repair Market, Canada, Revenue ($m), by Segment, 2018-2033
4.1.4 Soft Tissue Biologics Market, Canada, Revenue ($m), by Segment, 2018-2033
4.1.5 Viscosupplementation Market, Canada, Revenue ($m), by Segment, 2018-2033
4.2 Orthobiologics Market, Canada, Volume (Units), 2018-2033
4.2.1 Bone Grafts and Substitutes Market, Canada, Volume (Units), by Segment, 2018-2033
4.2.2 Bone Growth Stimulators Market, Canada, Volume (Units), by Segment, 2018-2033
4.2.3 Cartilage Repair Market, Canada, Volume (Units), by Segment, 2018-2033
4.2.4 Soft Tissue Biologics Market, Canada, Volume (Units), by Segment, 2018-2033
4.2.5 Viscosupplementation Market, Canada, Volume (Units), by Segment, 2018-2033
4.3 Orthobiologics Market, Canada, Average Price ($), 2018-2033
4.4 Orthobiologics Market, Canada, Company Share by Revenue ($m), 2025
5 Orthobiologics Market, Mexico
5.1 Orthobiologics Market, Mexico, Revenue ($m), 2018-2033
5.1.1 Bone Grafts and Substitutes Market, Mexico, Revenue ($m), by Segment, 2018-2033
5.1.2 Bone Growth Stimulators Market, Mexico, Revenue ($m), by Segment, 2018-2033
5.1.3 Cartilage Repair Market, Mexico, Revenue ($m), by Segment, 2018-2033
5.1.4 Soft Tissue Biologics Market, Mexico, Revenue ($m), by Segment, 2018-2033
5.1.5 Viscosupplementation Market, Mexico, Revenue ($m), by Segment, 2018-2033
5.2 Orthobiologics Market, Mexico, Volume (Units), 2018-2033
5.2.1 Bone Grafts and Substitutes Market, Mexico, Volume (Units), by Segment, 2018-2033
5.2.2 Bone Growth Stimulators Market, Mexico, Volume (Units), by Segment, 2018-2033
5.2.3 Cartilage Repair Market, Mexico, Volume (Units), by Segment, 2018-2033
5.2.4 Soft Tissue Biologics Market, Mexico, Volume (Units), by Segment, 2018-2033
5.2.5 Viscosupplementation Market, Mexico, Volume (Units), by Segment, 2018-2033
5.3 Orthobiologics Market, Mexico, Average Price ($), 2018-2033
5.4 Orthobiologics Market, Mexico, Company Share by Revenue ($m), 2025
6 Orthobiologics Market, United States
6.1 Orthobiologics Market, United States, Revenue ($m), 2018-2033
6.1.1 Bone Grafts and Substitutes Market, United States, Revenue ($m), by Segment, 2018-2033
6.1.2 Bone Growth Stimulators Market, United States, Revenue ($m), by Segment, 2018-2033
6.1.3 Cartilage Repair Market, United States, Revenue ($m), by Segment, 2018-2033
6.1.4 Soft Tissue Biologics Market, United States, Revenue ($m), by Segment, 2018-2033
6.1.5 Viscosupplementation Market, United States, Revenue ($m), by Segment, 2018-2033
6.2 Orthobiologics Market, United States, Volume (Units), 2018-2033
6.2.1 Bone Grafts and Substitutes Market, United States, Volume (Units), by Segment, 2018-2033
6.2.2 Bone Growth Stimulators Market, United States, Volume (Units), by Segment, 2018-2033
6.2.3 Cartilage Repair Market, United States, Volume (Units), by Segment, 2018-2033
6.2.4 Soft Tissue Biologics Market, United States, Volume (Units), by Segment, 2018-2033
6.2.5 Viscosupplementation Market, United States, Volume (Units), by Segment, 2018-2033
6.3 Orthobiologics Market, United States, Average Price ($), 2018-2033
6.4 Orthobiologics Market, United States, Company Share by Revenue ($m), 2025
7 Overview of Key Companies in North America Orthobiologics Market
7.1 Medtronic Plc
7.1.1 Company Overview
7.2 Sanofi
7.2.1 Company Overview
7.3 Bioventus Inc
7.3.1 Company Overview
7.4 Stryker Corp
7.4.1 Company Overview
7.5 Orthofix Holdings Inc
7.5.1 Company Overview
7.6 Zimmer Biomet Holdings Inc
7.6.1 Company Overview
7.7 Orthofix Medical Inc
7.7.1 Company Overview
7.8 Enovis Corp
7.8.1 Company Overview
7.9 Arthrex Inc
7.9.1 Company Overview
7.10 Globus Medical Inc
7.10.1 Company Overview
7.11 DePuy Synthes Inc
7.11.1 Company Overview
7.12 Xtant Medical Holdings Inc
7.12.1 Company Overview
7.13 Smith & Nephew Plc
7.13.1 Company Overview
7.14 Ferring Pharmaceuticals AS
7.14.1 Company Overview
7.15 LifeNet Health Inc
7.15.1 Company Overview
7.16 Highridge Inc
7.16.1 Company Overview
7.17 CONMED Corp
7.17.1 Company Overview
7.18 Fidia farmaceutici SpA
7.18.1 Company Overview
7.19 AlloSource
7.19.1 Company Overview
7.20 Seikagaku Corp
7.20.1 Company Overview
7.21 Anika Therapeutics Inc
7.21.1 Company Overview
7.22 Avanos Medical Inc
7.22.1 Company Overview
8 Orthobiologics Market Pipeline Products
9 Recent Developments
9.1 Corporate Communications
9.1.1 Nov 25, 2025: SNF Agora Institute at Johns Hopkins Begins Search for Next Director
9.1.2 Nov 21, 2025: Surgeons Collaborate to Treat War Injuries in Ukraine
9.1.3 Nov 21, 2025: Daniel Weiss to Leave Johns Hopkins to Lead Philadelphia Art Museum
9.1.4 Nov 19, 2025: LEM Surgical Completes First U.S. Clinical Procedures
9.1.5 Nov 18, 2025: Alafair Biosciences Announces First Clinical Use of Versacoat Flowable Hydrogel in Foot and Ankle and Hand and Wrist Procedures
9.1.6 Nov 14, 2025: Roots Equity Group Acquires Innovasis Medical and Appoints Matt Stuttle as CEO
9.1.7 Nov 14, 2025: Zavation Medical Products Launches NanoPrime: A New Hybrid Implant Material
9.1.8 Nov 14, 2025: PetVivo Reports Fiscal Q2 2026 Results With Revenues Up 50%
9.1.9 Nov 13, 2025: Dr. Marisa Ames Elected President of American Heartworm Society
9.1.10 Nov 12, 2025: Local Research Focuses On Using Novel Cell Therapy To Repair A Common Knee Injury
9.1.11 Nov 07, 2025: Ganesan Appointed Commissioner for the Commission on Dental Accreditation
9.1.12 Nov 06, 2025: Paho Promotes Interregional Cooperation to Strengthen Health Autonomy in Latin America and the Caribbean
9.1.13 Nov 06, 2025: Applications Open For Catalyst And Discovery Awards
9.1.14 Nov 04, 2025: $1M Grant from Maryland Stem Cell Research Fund Supports Adipose Tissue Allograft Therapy for Osteoarthritis
9.1.15 Oct 29, 2025: Regenerative Medicine Also Known As Stem Cell Therapy
9.1.16 Oct 28, 2025: Alira Health Advises Andera Partners On Strategic Investment In Adler Ortho
9.1.17 Oct 25, 2025: Vidal Appointed Head Of Operative Dentistry
9.1.18 Oct 23, 2025: Integrum Announces Organizational Restructuring to Strengthen Its Commercial Focus
9.1.19 Oct 20, 2025: Committee Tasked With Strategic Planning for JHU's Research Core Facilities
9.1.20 Oct 15, 2025: International Writing Program Director Steps Down After 25 Years
9.1.21 Oct 02, 2025: Gimv Invests CHF 28 Million in Spineart
9.1.22 Oct 01, 2025: Johns Hopkins, Other Large Nonprofits To Double Annual Contribution To Baltimore
9.1.23 Sep 23, 2025: Lifecore Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)
9.1.24 Sep 23, 2025: DJ Babu Joins Peabody Conservatory Hip-Hop Faculty
9.1.25 Sep 12, 2025: Engineers Develop Mini Microscope for Real-Time Brain Imaging
9.1.26 Jul 08, 2025: Medtronic Appoints Chad Spooner as Chief Financial Officer of MiniMed
9.1.27 May 21, 2025: Medtronic Announces Leadership Change in Cardiovascular Portfolio
9.2 Financial Announcements
9.2.1 Jan 07, 2026: Globus Medical Reports Preliminary Record Fourth Quarter and Full Year Sales Results
9.2.2 Nov 18, 2025: Aurora Spine Corporation Reports Record Third Quarter Financial Results
9.2.3 Nov 14, 2025: PetVivo Reports Fiscal Q2 2026 Results With Revenues Up 50%
9.2.4 Nov 13, 2025: SINTX Reports Third Quarter Business Update and Financial Highlights
9.2.5 Nov 06, 2025: Vericel Reports Third Quarter 2025 Financial Results
9.2.6 Oct 30, 2025: Lineage Cell Therapeutics to Report Third Quarter 2025 Financial Results and Provide Business Update November 6, 2025
9.2.7 Oct 23, 2025: Ocugen to Host Webcast on November 5, 2025 to Discuss Business Updates and Financial Results
9.2.8 May 05, 2025: Integra LifeSciences Reports First Quarter 2025 Financial Results
9.2.9 Apr 18, 2025: Integra LifeSciences to Host First Quarter 2025 Financial Results Conference Call on May 5, 2025
9.2.10 Apr 16, 2025: Assure Tech (Hangzhou) Receives CLIA Approval for FaStep Multi-Drug Urine Test Panel
9.3 Government and Public Interest
9.3.1 Mar 03, 2026: Vericel to Present at Multiple Upcoming Investor Conferences
9.3.2 Dec 01, 2025: Integra LifeSciences Leadership to Present at Citi 2025 Global Healthcare Conference
9.3.3 Nov 20, 2025: Ocugen CEO To Present At NobleCon21
9.3.4 Nov 10, 2025: MIMEDX to Participate in Upcoming Investor Conferences
9.3.5 Oct 02, 2025: Ocugen to Present at Industry and Investor Conferences in October 2025
9.3.6 Sep 02, 2025: Ocugen to Participate in H.C. Wainwright 27th Annual Global Investment Conference & Biotech on Tap 2025
9.3.7 Aug 29, 2025: Integra LifeSciences Leadership to Present at Wells Fargo and Morgan Stanley Healthcare Investor Conferences
9.3.8 Aug 08, 2025: Alphatec Holdings to Participate in Upcoming Conferences
9.3.9 Jun 19, 2025: Mah Sing Healthcare Sdn Bhd Receives 510(K) Clearance For Nitrile Powder Free Examination Glove with Tremella Fuciformis Extract
9.3.10 Apr 10, 2025: New Study Shows Arima Genomics’ Technology Detects Actionable Cancer Drivers in Solid Tumors Missed by Standard Tests
9.4 Legal And Regulatory
9.4.1 Jun 13, 2025: FDA Approves Immune Checkpoint Inhibitor Drug for Patients With Resectable Locally Advanced Head and Neck Cancer, Backed by Dana-Farber Research
9.4.2 Jun 04, 2025: Glucotrack to Showcase Long-Term Continuous Blood Glucose Monitor at American Diabetes Association’s 85th Scientific Sessions
9.4.3 Apr 15, 2025: Hangzhou SHINING3D Dental Technology Receives 510(K) Clearance For DT20 Denture Base Resin
9.5 Other Significant Developments
9.5.1 Nov 19, 2025: LEM Surgical Completes First U.S. Clinical Procedures
9.5.2 Nov 18, 2025: CurvaFix Expands National Market Access With Premier Inc. for General Orthopedic Trauma Products
9.5.3 Nov 14, 2025: Intrinsic Therapeutics Completes First Endoscopic Barricaid Implantation in Great Lakes Region
9.5.4 Nov 13, 2025: Curiteva Announces Publication of Peer-Reviewed Study in Journal of Biomaterials
9.5.5 Nov 13, 2025: NavJam LLC Forms Global Distribution Partnership with Ruthless Spine
9.5.6 Nov 04, 2025: $1M Grant from Maryland Stem Cell Research Fund Supports Adipose Tissue Allograft Therapy for Osteoarthritis
9.5.7 Nov 03, 2025: SINTX Technologies Launches OsseoSculpt Biologic for SINAPTIC Foot & Ankle System
9.5.8 Oct 23, 2025: Integrum Announces Organizational Restructuring to Strengthen Its Commercial Focus
9.5.9 Oct 08, 2025: Linshom Medical Receives 510(K) Clearance For Continuous Predictive Respiratory Monitoring System (CPRMS)
9.5.10 Oct 03, 2025: HCA HealthONE Pediatric Scoliosis and Spine Program Rebranded
9.5.11 Oct 01, 2025: Elutia Completes Sale of BioEnvelope Business to Boston Scientific for $88 Million
9.5.12 Sep 29, 2025: D. Boral Capital to Host KOL Webinar With World Leading Experts Featuring Insights & Breakthroughs from Enlivex’s Knee Osteoarthritis Program
9.5.13 Sep 17, 2025: FAU/Baptist Health AI Spine Model Could Transform Back Pain Treatment
9.5.14 Aug 30, 2025: Blood-Pressure Reductions With Baxdrostat in Patients With Uncontrolled or Resistant Hypertension
9.5.15 May 20, 2025: APEX Biologix Enters Exclusive U.S. Distribution Agreement with Bioventus LLC for XCELL PRP System
9.6 Product News
9.6.1 Jan 14, 2026: MTF Biologics and Kolosis BIO Introduce Summit Matrix for Orthopedic and Spinal Surgeries
9.6.2 Nov 19, 2025: LEM Surgical Completes First U.S. Clinical Procedures
9.6.3 Nov 18, 2025: Aurora Spine Corporation Reports Record Third Quarter Financial Results
9.6.4 Nov 18, 2025: CurvaFix Expands National Market Access With Premier Inc. for General Orthopedic Trauma Products
9.6.5 Nov 15, 2025: Zavation Medical Products Announces First Implantations of Varisync ALIF NanoPrime
9.6.6 Nov 14, 2025: Zimmer Biomet Secures FDA Clearance for Enhanced ROSA Knee Robotic Technology
9.6.7 Nov 14, 2025: Intrinsic Therapeutics Completes First Endoscopic Barricaid Implantation in Great Lakes Region
9.6.8 Nov 14, 2025: PetVivo Reports Fiscal Q2 2026 Results With Revenues Up 50%
9.6.9 Nov 13, 2025: Implanet Signs Partnership Agreement With 8i Robotics Inc. For Clinical Evaluation Of Robotic Spine Surgery System
9.6.10 Nov 13, 2025: Icotec Receives FDA Clearance for CMORE CT System, Expanding BlackArmor Engineered Carbon/PEEK Technology
9.6.11 Nov 13, 2025: Curiteva Announces Publication of Peer-Reviewed Study in Journal of Biomaterials
9.6.12 Nov 13, 2025: Texas A&M Researchers Discover Key to Regrowing Limbs
9.6.13 Nov 13, 2025: Captiva Spine Receives FDA Clearance for Flat-Panel C-Arm Calibrators and AI-Assisted Registration
9.6.14 Nov 13, 2025: SINTX Reports Third Quarter Business Update and Financial Highlights
9.6.15 Nov 13, 2025: Curiteva Announces Publication of Peer-Reviewed Study in Journal of Biomaterials
9.6.16 Nov 07, 2025: 3D Nerve Maps Enhance Precision in Bone Repair
9.6.17 Nov 04, 2025: RevBio Receives First FDA Approval for Bone Glue to Treat Extremity Fractures
9.6.18 Nov 04, 2025: $1M Grant from Maryland Stem Cell Research Fund Supports Adipose Tissue Allograft Therapy for Osteoarthritis
9.6.19 Nov 03, 2025: EmeTerm Wristband Reduces Postoperative Nausea and Vomiting in Orthopedic Surgeries
9.6.20 Oct 29, 2025: 4-Web Cervical Disc Fusion Study Now Enrolling
9.6.21 Oct 29, 2025: Cooper and Inspira Neuroscience Perform New Jersey’s First Fully Endoscopic Laminectomy
9.6.22 Oct 28, 2025: Zimmer Biomet Receives FDA Breakthrough Designation for Iodine-Treated Total Hip Replacement System
9.6.23 Oct 27, 2025: Aurora Spine Introduces New Biologics Division
9.6.24 Oct 21, 2025: Onkos Surgical Receives FDA Clearance for ELEOS Proximal Tibia with Antibacterial Technology
9.6.25 Oct 21, 2025: Zimmer Biomet Showcases Robotics and Musculoskeletal Innovations at AAHKS Annual Meeting
9.6.26 Oct 21, 2025: Bone Solutions’ Mg OSTEOCRETE and Mg OSTEOINJECT Get FDA Clearance for Pediatric Use
9.6.27 Oct 20, 2025: Biedermann Motech Expands MOSS!MODULARITY Platform with New Product Introductions
9.6.28 Oct 20, 2025: SINTX Technologies Receives FDA Clearance for Sinaptic Foot & Ankle Implant System
9.6.29 Oct 12, 2025: Mesenchymal Stem Cell Therapy For Multiple Sclerosis: Promising Clinical Research Results
9.6.30 Oct 07, 2025: Zimmer Biomet Completes Acquisition of Monogram Technologies
9.6.31 Oct 06, 2025: I2Pure Celebrates Zimmer Biomet's Approval of Iodine-Treated Implant System
9.6.32 Oct 01, 2025: Orthocell Appoints First Distributor For Remplir In Canadian Market
9.6.33 Oct 01, 2025: Bioretec's RemeOs Screw LAG Solid Receives CMS Transitional Pass-Through Payment
9.6.34 Oct 01, 2025: FDA Grants Clearance For Planmed XFI Full-Body Weight-Bearing CT Scanner
9.6.35 Sep 30, 2025: Vivex Biologics Treats First Patient in Restore Trial for Degenerative Disc Disease
9.6.36 Sep 25, 2025: Zimmer Biomet Receives Japan PMDA Approval for Iodine-Treated Total Hip Replacement System
9.6.37 Sep 23, 2025: Arthrex Completes First Case With NanoNeedle Scope
2.0
9.6.38 Sep 18, 2025: Brainlab Secures FDA 510(k) Clearance and Launches Spine Mixed Reality Navigation
9.6.39 Sep 17, 2025: First Touch CMC 1 Prosthesis Implanted in the United States
9.6.40 Sep 17, 2025: FAU/Baptist Health AI Spine Model Could Transform Back Pain Treatment
9.6.41 Sep 12, 2025: Bioretec Provides Update on RemeOs DrillPin Commercialization
9.6.42 Sep 10, 2025: OrthoPediatrics Corp. Completes First Procedures with VerteGlide Spinal Growth Guidance System
9.6.43 Sep 09, 2025: Medline Unite to Introduce Achilles Repair Systems at AOFAS 2025 Meeting
9.6.44 Apr 23, 2025: Assure Tech Receives CLIA Approval for Healcare Panel Dip Test
9.7 Research And Development
9.7.1 Nov 12, 2025: Local Research Focuses On Using Novel Cell Therapy To Repair A Common Knee Injury
9.8 Strategy And Business Planning
9.8.1 Nov 18, 2025: CurvaFix Expands National Market Access With Premier Inc. for General Orthopedic Trauma Products
9.8.2 Nov 14, 2025: PetVivo Reports Fiscal Q2 2026 Results With Revenues Up 50%
9.8.3 Nov 13, 2025: NavJam LLC Forms Global Distribution Partnership with Ruthless Spine
9.8.4 Nov 03, 2025: LISI Group Confirms Sale of LISI MEDICAL Division to SK Capital
9.8.5 Oct 28, 2025: Spartan Medical And Diamond Orthopedic Form Strategic Partnership
9.8.6 Oct 28, 2025: Alira Health Advises Andera Partners On Strategic Investment In Adler Ortho
9.8.7 Oct 28, 2025: Scoliosis Research Society Forms New Partnership with EUROSPINE
9.8.8 Oct 20, 2025: Biedermann Motech Expands MOSS!MODULARITY Platform with New Product Introductions
9.8.9 Oct 02, 2025: Gimv Invests CHF 28 Million in Spineart
9.8.10 Oct 01, 2025: Orthocell Appoints First Distributor For Remplir In Canadian Market
9.8.11 Oct 01, 2025: Elutia Completes Sale of BioEnvelope Business to Boston Scientific for $88 Million
9.8.12 Sep 29, 2025: RMTG Partners With BKFC As Official Regenerative Medicine Provider
9.8.13 Sep 17, 2025: Keensight Capital Acquires Majority Stake in Isto Biologics from Thompson Street Capital Partners
10 Appendix
10.1 Research Methodology
10.1.1 Coverage
10.1.2 Secondary Research
10.1.3 Primary Research
10.1.4 Market Modeling and Forecasting
10.1.5 Company Share Analysis
10.1.6 Benchmarking
10.2 GlobalData Consulting
10.3 Contact Us
10.4 Disclaimer
