Primary Immune Deficiency (PID) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

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Primary immunodeficiency is defined as a weakened immune system that results in repeated infections and other health problems occurring more easily. Signs and symptoms include blood infections, pneumonia, bronchitis, sinus infections, ear infections, meningitis or skin infections, digestive problems, such as cramping, loss of appetite, nausea, and diarrhea.

The Primary Immune Deficiency drugs in development market research report provide comprehensive information on the therapeutics under development for Primary Immune Deficiency, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA), and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history, and the latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for Primary Immune Deficiency and features dormant and discontinued projects.

Key Targets in the Primary Immune Deficiency Pipeline Products Market

The key targets in the Primary Immune Deficiency pipeline products market are Cytokine Receptor Common Subunit Gamma, C-X-C Chemokine Receptor Type 4, Adenosine Deaminase, Protein Artemis, CD40 Ligand, Immunoglobulin G, Interleukin 2 Receptor, Mast/Stem Cell Growth Factor Receptor Kit, Phosphatidylinositol 4,5 Bisphosphate 3 Kinase Catalytic Subunit Delta Isoformy, Serine/Threonine Protein Kinase mTOR, and others.

Primary Immune Deficiency Pipeline Products Analysis Market by Targets

Primary Immune Deficiency Pipeline Products Analysis Market by Targets

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Key Mechanisms of Action in the Primary Immune Deficiency Pipeline Products Market

The key mechanisms of action in the Primary Immune Deficiency pipeline products market are Cytokine Receptor Common Subunit Gamma Activator, C-X-C Chemokine Receptor Type 4 Antagonist, Adenosine Deaminase Activator, Protein Artemis Activator, CD40 Ligand Activator, Interleukin 2 Receptor Agonist, Mast/Stem Cell Growth Factor Receptor Kit Antagonist, Phosphatidylinositol 4,5 Bisphosphate 3 Kinase Catalytic Subunit Delta Isoform Inhibitor, Serine/Threonine Protein Kinase mTOR Inhibitor, Signal Transducer And Activator Of Transcription 3 Activator, and others.

Primary Immune Deficiency Pipeline Products Market Analysis by Mechanism of Actions

Primary Immune Deficiency Pipeline Products Market Analysis by Mechanism of Actions

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Key Routes of Administration in the Primary Immune Deficiency Pipeline Products Market

The key routes of administration in the Primary Immune Deficiency pipeline products market are intravenous, parenteral, subcutaneous, oral, intramuscular, and topical.

Primary Immune Deficiency Pipeline Products Market Analysis by Routes of Administration

Primary Immune Deficiency Pipeline Products Market Analysis by Routes of Administration

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Key Molecule Types in the Primary Immune Deficiency Pipeline Products Market

The key molecule types in the Primary Immune Deficiency pipeline products market are gene-modified cell therapy, antibody, small molecule, cell therapy, biologic, gene therapy, monoclonal antibody, recombinant enzyme, and recombinant protein.

Primary Immune Deficiency Pipeline Products Market Analysis by Molecule Type

Primary Immune Deficiency Pipeline Products Market Analysis by Molecule Type

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Major Companies in the Primary Immune Deficiency Pipeline Products Market

Some of the major companies in the Primary Immune Deficiency pipeline products market are Takeda Pharmaceutical Co Ltd, X4 Pharmaceuticals Inc, ADMA Biologics Inc, Cellectis SA, Grifols SA, Mustang Bio Inc, Biotest AG, Cellective BioTherapy Inc, Chengdu Rongsheng Pharmaceutical Co Ltd, and Clinigen Group Plc.

Primary Immune Deficiency Pipeline Products Market Analysis by Companies

Primary Immune Deficiency Pipeline Products Market Analysis by Companies

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Market Report Overview

Key targets Cytokine Receptor Common Subunit Gamma, C-X-C Chemokine Receptor Type 4, Adenosine Deaminase, Protein Artemis, CD40 Ligand, Immunoglobulin G, Interleukin 2 Receptor, Mast/Stem Cell Growth Factor Receptor Kit, Phosphatidylinositol 4,5 Bisphosphate 3 Kinase Catalytic Subunit Delta Isoformy, Serine/Threonine Protein Kinase mTOR, and Others
Key mechanism of action Cytokine Receptor Common Subunit Gamma Activator, C-X-C Chemokine Receptor Type 4 Antagonist, Adenosine Deaminase Activator, Protein Artemis Activator, CD40 Ligand Activator, Interleukin 2 Receptor Agonist, Mast/Stem Cell Growth Factor Receptor Kit Antagonist, Phosphatidylinositol 4,5 Bisphosphate 3 Kinase Catalytic Subunit Delta Isoform Inhibitor, Serine/Threonine Protein Kinase mTOR Inhibitor, Signal Transducer And Activator Of Transcription 3 Activator, and Others
Key routes of administration Intravenous, Parenteral, Subcutaneous, Oral, Intramuscular, and Topical
Key molecule type Gene-Modified Cell Therapy, Antibody, Small Molecule, Cell Therapy, Biologic, Gene Therapy, Monoclonal Antibody, Recombinant Enzyme, and Recombinant Protein
Major companies Takeda Pharmaceutical Co Ltd, X4 Pharmaceuticals Inc, ADMA Biologics Inc, Cellectis SA, Grifols SA, Mustang Bio Inc, Biotest AG, Cellective BioTherapy Inc, Chengdu Rongsheng Pharmaceutical Co Ltd, and Clinigen Group Plc

Scope

  • The pipeline guide provides a snapshot of the global therapeutic landscape of Primary Immune Deficiency (PID) (Genetic Disorders).
  • The pipeline guide reviews pipeline therapeutics for Primary Immune Deficiency (PID) (Genetic Disorders) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Primary Immune Deficiency (PID) (Genetic Disorders) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Primary Immune Deficiency (PID) (Genetic Disorders) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA), and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews the latest news related to pipeline therapeutics for Primary Immune Deficiency (PID) (Genetic Disorders)

Reasons to Buy

  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Primary Immune Deficiency (PID) (Genetic Disorders).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and their most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Primary Immune Deficiency (PID) (Genetic Disorders) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from the pipeline.

ADMA Biologics Inc
Biotest AG
Cellectis SA
Cellective BioTherapy Inc
Chengdu Rongsheng Pharmaceutical Co Ltd
Clinigen Group Plc
CSL Ltd
EmendoBio Inc
Evolve Biologics Inc
Genespire Srl
Graphite Bio Inc
Grifols SA
Grifols Therapeutics Inc
Jasper Therapeutics Inc
Kedrion SpA
Lactiga Inc
Liminal BioSciences Inc
Microgen
Mustang Bio Inc
Noga Therapeutics Ltd
Novartis AG
Octapharma AG
Orchard Therapeutics Plc
Pfizer Inc
Smart Immune SAS
Sumitomo Dainippon Pharma Co Ltd
Taiga Biotechnologies Inc
Takeda Pharmaceutical Co Ltd
X4 Pharmaceuticals Inc

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Primary Immune Deficiency (PID) – Overview

Primary Immune Deficiency (PID) – Therapeutics Development

Pipeline Overview

Pipeline by Companies

Pipeline by Universities/Institutes

Products under Development by Companies

Products under Development by Universities/Institutes

Primary Immune Deficiency (PID) – Therapeutics Assessment

Assessment by Target

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Primary Immune Deficiency (PID) – Companies Involved in Therapeutics Development

ADMA Biologics Inc

Biotest AG

Cellectis SA

Cellective BioTherapy Inc

Chengdu Rongsheng Pharmaceutical Co Ltd

Clinigen Group Plc

CSL Ltd

EmendoBio Inc

Evolve Biologics Inc

Genespire Srl

Graphite Bio Inc

Grifols SA

Grifols Therapeutics Inc

Jasper Therapeutics Inc

Kedrion SpA

Lactiga Inc

Liminal BioSciences Inc

Microgen

Mustang Bio Inc

Noga Therapeutics Ltd

Novartis AG

Octapharma AG

Orchard Therapeutics Plc

Pfizer Inc

Smart Immune SAS

Sumitomo Dainippon Pharma Co Ltd

Taiga Biotechnologies Inc

Takeda Pharmaceutical Co Ltd

X4 Pharmaceuticals Inc

Primary Immune Deficiency (PID) – Drug Profiles

aldesleukin – Drug Profile

Product Description

Mechanism Of Action

History of Events

BioGam – Drug Profile

Product Description

Mechanism Of Action

Biologic 1 for Genetic Disorders and Infectious Disease – Drug Profile

Product Description

Mechanism Of Action

Biologic for Genetic Disorders and Infectious Disease – Drug Profile

Product Description

Mechanism Of Action

BT-595 – Drug Profile

Product Description

Mechanism Of Action

History of Events

Cellular Immunotherapy for Severe Combined Immune Deficiency and Graft Versus Host Disease – Drug Profile

Product Description

Mechanism Of Action

Cuvitru – Drug Profile

Product Description

Mechanism Of Action

History of Events

EMD-102 – Drug Profile

Product Description

Mechanism Of Action

Gene Therapies for Primary Immune Deficiency – Drug Profile

Product Description

Mechanism Of Action

Gene Therapy for Primary Immune Deficiency – Drug Profile

Product Description

Mechanism Of Action

Gene Therapy for X-Linked SCID – Drug Profile

Product Description

Mechanism Of Action

History of Events

Gene Therapy for X-Linked SCID – Drug Profile

Product Description

Mechanism Of Action

History of Events

Gene Therapy to Activate Adenosine Deaminase for Adenosine Deaminase Deficiency Related SCID – Drug Profile

Product Description

Mechanism Of Action

History of Events

Gene Therapy to Activate Adenosine Deaminase for Adenosine Deaminase Deficiency Related SCID – Drug Profile

Product Description

Mechanism Of Action

History of Events

Gene Therapy to Activate Adenosine Deaminase for Severe Combined Immune Deficiency – Drug Profile

Product Description

Mechanism Of Action

History of Events

Gene Therapy to Activate Artemis for Severe Combined Immune Deficiency – Drug Profile

Product Description

Mechanism Of Action

History of Events

Gene Therapy to Activate Artemis for Severe Combined Immunodeficiency – Drug Profile

Product Description

Mechanism Of Action

Gene Therapy to Activate IL-2 Gamma Receptor for SCID-X1 – Drug Profile

Product Description

Mechanism Of Action

History of Events

Gene Therapy to Activate IL-2 Gamma Receptor for X-Linked SCID – Drug Profile

Product Description

Mechanism Of Action

History of Events

Gene Therapy to Activate IL2RG for SCID-X1 – Drug Profile

Product Description

Mechanism Of Action

History of Events

Gene Therapy to Activate IL2RG for X-Linked SCID – Drug Profile

Product Description

Mechanism Of Action

GENE-101 – Drug Profile

Product Description

Mechanism Of Action

History of Events

GPH-201 – Drug Profile

Product Description

Mechanism Of Action

History of Events

hyaluronidase (recombinant, human) + immune globulin (human) – Drug Profile

Product Description

Mechanism Of Action

History of Events

immune globulin (human) – Drug Profile

Product Description

Mechanism Of Action

History of Events

immune globulin (human) – Drug Profile

Product Description

Mechanism Of Action

History of Events

immune globulin (human) – Drug Profile

Product Description

Mechanism Of Action

History of Events

immune globulin (human) – Drug Profile

Product Description

Mechanism Of Action

History of Events

immune globulin (human) – Drug Profile

Product Description

Mechanism Of Action

History of Events

immune globulin (human) – Drug Profile

Product Description

Mechanism Of Action

IVIG-PEG – Drug Profile

Product Description

Mechanism Of Action

History of Events

JSP-191 – Drug Profile

Product Description

Mechanism Of Action

History of Events

LCTG-001 – Drug Profile

Product Description

Mechanism Of Action

leniolisib – Drug Profile

Product Description

Mechanism Of Action

History of Events

mavorixafor – Drug Profile

Product Description

Mechanism Of Action

History of Events

MB-107 – Drug Profile

Product Description

Mechanism Of Action

History of Events

MB-109 – Drug Profile

Product Description

Mechanism Of Action

History of Events

Octanorm – Drug Profile

Product Description

Mechanism Of Action

History of Events

RecIG – Drug Profile

Product Description

Mechanism Of Action

Rethymic – Drug Profile

Product Description

Mechanism Of Action

History of Events

simoladagene autotemcel – Drug Profile

Product Description

Mechanism Of Action

History of Events

sirolimus – Drug Profile

Product Description

Mechanism Of Action

History of Events

Small Molecule to Inhibit CXCL12 for WHIM Syndrome – Drug Profile

Product Description

Mechanism Of Action

History of Events

SMART-101 – Drug Profile

Product Description

Mechanism Of Action

History of Events

TAK-880 – Drug Profile

Product Description

Mechanism Of Action

TAK-881 – Drug Profile

Product Description

Mechanism Of Action

History of Events

TalX-02 – Drug Profile

Product Description

Mechanism Of Action

TalX-03 – Drug Profile

Product Description

Mechanism Of Action

TBX-1400 – Drug Profile

Product Description

Mechanism Of Action

History of Events

X-4P003 – Drug Profile

Product Description

Mechanism Of Action

History of Events

Primary Immune Deficiency (PID) – Dormant Projects

Primary Immune Deficiency (PID) – Discontinued Products

Primary Immune Deficiency (PID) – Product Development Milestones

Featured News & Press Releases

Dec 02, 2021: X4 Pharmaceuticals to host virtual seminar “Understanding Primary Immunodeficiencies” to highlight broadening market opportunities for mavorixafor

Oct 04, 2021: X4 Pharmaceuticals completes enrollment in phase 3 mavorixafor trial in patients with WHIM Syndrome

Aug 03, 2021: X4 Pharmaceuticals announces key enrollment milestone achievements in ongoing mavorixafor clinical trials and reports second quarter financial results

Jul 13, 2021: First patient treated in KIDCARES10, Kedrion Biopharma pediatric primary immunodeficiency study

May 17, 2021: Evolve Biologics confirms selection of DPR Construction as general contractor for first manufacturing facility in Texas, demonstrating further progress toward commercialization of Its innovative PlasmaCap EBA technology

Apr 01, 2021: First patient enrolled in KIDCARES10, Kedrion Biopharma pediatric Primary immunodeficiency study

Mar 10, 2021: Evolve Biologics provides business update on progress toward commercialization of innovative PlasmaCap EBA technology

Feb 09, 2021: Evolve Biologics completes phase III adult and pediatric trials for PlasmaCap IG (Intravenous Immunoglobulin)

Jan 11, 2021: CARES10 clinical trial: Last patient treated in the USA

Jan 04, 2021: Kedrion Biopharma phase III trial, CARES10, achieves important milestone: last patient treated

Dec 10, 2020: X4 Pharmaceuticals receives rare pediatric disease designation from FDA for Mavorixafor for the treatment of WHIM syndrome

Oct 08, 2020: X4 Pharmaceuticals announces fast track designation granted by the FDA to Mavorixafor for the treatment of WHIM Syndrome

Sep 15, 2020: European Medicines Agency approves label update for HYQVIA (human normal immunoglobulin 10% and recombinant human hyaluronidase), expanding its use to a broader group of patients with secondary immunodeficiencies

Sep 09, 2020: Heyu Medicine’s CXCR4 antagonist Mavorixafor obtains clinical trial approval in China

Sep 02, 2020: X4 Pharmaceuticals announces publication of mavorixafor phase 2 clinical data for treatment of WHIM Syndrome in ‘Blood’ – the Official Journal of the American Society of Hematology

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

Table

List of Tables

Number of Products under Development for Primary Immune Deficiency (PID), 2022

Number of Products under Development by Companies, 2022

Number of Products under Development by Companies, 2022 (Contd..1)

Number of Products under Development by Universities/Institutes, 2022

Products under Development by Companies, 2022

Products under Development by Companies, 2022 (Contd..1)

Products under Development by Companies, 2022 (Contd..2)

Products under Development by Universities/Institutes, 2022

Number of Products by Stage and Target, 2022

Number of Products by Stage and Mechanism of Action, 2022

Number of Products by Stage and Route of Administration, 2022

Number of Products by Stage and Molecule Type, 2022

Primary Immune Deficiency (PID) – Pipeline by ADMA Biologics Inc, 2022

Primary Immune Deficiency (PID) – Pipeline by Biotest AG, 2022

Primary Immune Deficiency (PID) – Pipeline by Cellectis SA, 2022

Primary Immune Deficiency (PID) – Pipeline by Cellective BioTherapy Inc, 2022

Primary Immune Deficiency (PID) – Pipeline by Chengdu Rongsheng Pharmaceutical Co Ltd, 2022

Primary Immune Deficiency (PID) – Pipeline by Clinigen Group Plc, 2022

Primary Immune Deficiency (PID) – Pipeline by CSL Ltd, 2022

Primary Immune Deficiency (PID) – Pipeline by EmendoBio Inc, 2022

Primary Immune Deficiency (PID) – Pipeline by Evolve Biologics Inc, 2022

Primary Immune Deficiency (PID) – Pipeline by Genespire Srl, 2022

Primary Immune Deficiency (PID) – Pipeline by Graphite Bio Inc, 2022

Primary Immune Deficiency (PID) – Pipeline by Grifols SA, 2022

Primary Immune Deficiency (PID) – Pipeline by Grifols Therapeutics Inc, 2022

Primary Immune Deficiency (PID) – Pipeline by Jasper Therapeutics Inc, 2022

Primary Immune Deficiency (PID) – Pipeline by Kedrion SpA, 2022

Primary Immune Deficiency (PID) – Pipeline by Lactiga Inc, 2022

Primary Immune Deficiency (PID) – Pipeline by Liminal BioSciences Inc, 2022

Primary Immune Deficiency (PID) – Pipeline by Microgen, 2022

Primary Immune Deficiency (PID) – Pipeline by Mustang Bio Inc, 2022

Primary Immune Deficiency (PID) – Pipeline by Noga Therapeutics Ltd, 2022

Primary Immune Deficiency (PID) – Pipeline by Novartis AG, 2022

Primary Immune Deficiency (PID) – Pipeline by Octapharma AG, 2022

Primary Immune Deficiency (PID) – Pipeline by Orchard Therapeutics Plc, 2022

Primary Immune Deficiency (PID) – Pipeline by Pfizer Inc, 2022

Primary Immune Deficiency (PID) – Pipeline by Smart Immune SAS, 2022

Primary Immune Deficiency (PID) – Pipeline by Sumitomo Dainippon Pharma Co Ltd, 2022

Primary Immune Deficiency (PID) – Pipeline by Taiga Biotechnologies Inc, 2022

Primary Immune Deficiency (PID) – Pipeline by Takeda Pharmaceutical Co Ltd, 2022

Primary Immune Deficiency (PID) – Pipeline by X4 Pharmaceuticals Inc, 2022

Primary Immune Deficiency (PID) – Dormant Projects, 2022

Primary Immune Deficiency (PID) – Discontinued Products, 2022

Figures

List of Figures

Number of Products under Development for Primary Immune Deficiency (PID), 2022

Number of Products under Development by Companies, 2022

Number of Products under Development by Universities/Institutes, 2022

Number of Products by Top 10 Targets, 2022

Number of Products by Stage and Top 10 Targets, 2022

Number of Products by Top 10 Mechanism of Actions, 2022

Number of Products by Stage and Top 10 Mechanism of Actions, 2022

Number of Products by Routes of Administration, 2022

Number of Products by Stage and Routes of Administration, 2022

Number of Products by Top 10 Molecule Types, 2022

Number of Products by Stage and Top 10 Molecule Types, 2022

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