Serine/Threonine Protein Kinase A Raf (Proto Oncogene A Raf or Proto Oncogene Pks or ARAF or EC 2.7.11.1) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

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ARAF Drugs in Development Report Overview

Serine/threonine-protein kinase A-Raf is an enzyme involved in the transduction of mitogenic signals from the cell membrane to the nucleus. The Serine/Threonine Protein Kinase A Raf (Proto Oncogene A Raf or Proto Oncogene Pks or ARAF or EC 2.7.11.1) drugs in development research report provides comprehensive information on the therapeutics under development for ARAF. The report also analyzes the stage of development, mechanism of action (MoA), route of administration (RoA), molecule type, therapy area, and indication.

The pipeline report covers the descriptive pharmacological action and product description of ARAF. It includes the complete research and development history as well as the latest news and press releases. Additionally, the report provides an overview of key players involved in ARAF therapeutic development and features dormant and discontinued products.

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Key Therapy Areas ·       Oncology

·       Genetic Disorders

Key Indications ·       Colorectal Cancer

·       Melanoma

·       Solid Tumor

·       Blood Cancer

·       Craniopharyngioma

Key Mechanism of Action ·       Serine/Threonine Protein Kinase A Raf Inhibitor
Key Route of Administration ·       Oral
Key Molecule Type ·       Small Molecule
Leading Companies ·       Jazz Pharmaceuticals Plc

·       Samjin Pharm Co Ltd

·       Takeda Pharmaceutical Co Ltd

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ARAF Pipeline Products Segmentation by Therapy Areas

The key therapy areas associated with ARAF drugs in development include oncology and genetic disorders. Oncology had the highest share among ARAF drugs in development in 2022.

ARAF Pipeline Products Analysis by Therapy Areas, 2022 (%)

ARAF Pipeline Products Analysis by Therapy Areas, 2022 (%)

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ARAF Pipeline Products Segmentation by Indications

A few of the key indications for ARAF drug application include colorectal cancer, melanoma, solid tumor, blood cancer, and craniopharyngioma, among others. ARAF drugs had the highest number of products in development for colorectal cancer, melanoma, and solid tumor in 2022.

ARAF Pipeline Products Analysis by Indications, 2022 (%)

ARAF Pipeline Products Analysis by Indications, 2022 (%)

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ARAF Pipeline Products Segmentation by MoA, RoA, and Molecule Types

The mechanism of action in ARAF drugs in development is Serine/Threonine Protein Kinase A Raf Inhibitor and the key molecule type is the small molecule. Oral RoA was the only way for ARAF drug administration in 2022.

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ARAF Pipeline Products - Competitive Landscape

Takeda Pharmaceutical Co Ltd had the highest number of products in the ARAF pipeline in 2022

A few of the leading companies associated with ARAF pipeline products are:

  • Jazz Pharmaceuticals Plc
  • Samjin Pharm Co Ltd
  • Takeda Pharmaceutical Co Ltd

Takeda Pharmaceutical Co Ltd: Takeda Pharmaceutical is headquartered in Tokyo, Japan. It is a research-based pharmaceutical company that focuses on the discovery, development, manufacturing, marketing, commercialization, import, and export of pharmaceutical drugs. The company offers products in the areas of rare diseases, gastrointestinal, and oncology, among others. It markets products directly and through a network of wholesale distributors, retail chains, and other purchasing groups worldwide.

ARAF Pipeline Products Analysis by Companies, 2022 (%)

ARAF Pipeline Products Analysis by Companies, 2022 (%)

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ARAF Pipeline Products - Featured News

11th November 2022: Day One Biopharmaceuticals is a clinical-stage biopharmaceutical company dedicated to developing and commercializing targeted therapies for people of all ages with life-threatening diseases. It announced two upcoming presentations at the Society for Neuro-Oncology (SNO) annual meeting that was held from November 16-20, 2022 in Tampa, Florida.

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Segments Covered in the Report

ARAF Pipeline Products Therapy Area Outlook (2022)

  • Oncology
  • Genetic Disorders

ARAF Pipeline Products Indication Outlook (2022)

  • Colorectal Cancer
  • Melanoma
  • Solid Tumor
  • Blood Cancer
  • Craniopharyngioma

ARAF Pipeline Products MoA Outlook (2022)

  • Serine/Threonine Protein Kinase A Raf Inhibitor

ARAF Pipeline Products RoA Outlook (2022)

  • Oral

ARAF Pipeline Products Molecule Type Outlook (2022)

  • Small molecule

Scope

The report provides:

  • A snapshot of the global therapeutic landscape of Serine/Threonine Protein Kinase A Raf.
  • Review of pipeline therapeutics for Serine/Threonine Protein Kinase A Raf by companies and universities/research institutes. The review is based on information derived from company and industry-specific sources.
  • Information about pipeline products based on several stages of development ranging from pre-registration to discovery and undisclosed stages.
  • Descriptive drug profiles for the pipeline products which comprise product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • Key companies involved in Serine/Threonine Protein Kinase A Raf therapeutics and enlist all their major and minor products.
  • Evaluation of Serine/Threonine Protein Kinase A Raf therapeutics based on their mechanism of action (MoA), drug target, route of administration (RoA), and molecule type.
  • All the dormant and discontinued pipeline products.
  • Reviews of the latest news related to pipeline therapeutics for Serine/Threonine Protein Kinase A Raf.

Reasons to Buy

  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolios and create effective counterstrategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Serine/Threonine Protein Kinase A Raf.
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies in the Serine/Threonine Protein Kinase A Raf market.
  • Plan mergers and acquisitions meritoriously by identifying key players and their most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding the Serine/Threonine Protein Kinase A Raf pipeline depth and the focus on indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive products to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued products and applying this knowledge to pipeline development.

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Serine/Threonine Protein Kinase A Raf (Proto Oncogene A Raf or Proto Oncogene Pks or ARAF or EC

2.7.11.1) – Overview

Serine/Threonine Protein Kinase A Raf (Proto Oncogene A Raf or Proto Oncogene Pks or ARAF or EC

2.7.11.1) – Therapeutics Development

Products under Development by Stage of Development

Products under Development by Therapy Area

Products under Development by Indication

Products under Development by Companies

Products under Development by Universities/Institutes

Serine/Threonine Protein Kinase A Raf (Proto Oncogene A Raf or Proto Oncogene Pks or ARAF or EC

2.7.11.1) – Therapeutics Assessment

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Serine/Threonine Protein Kinase A Raf (Proto Oncogene A Raf or Proto Oncogene Pks or ARAF or EC

2.7.11.1) – Companies Involved in Therapeutics Development

Jazz Pharmaceuticals Plc

Samjin Pharm Co Ltd

Takeda Pharmaceutical Co Ltd

Serine/Threonine Protein Kinase A Raf (Proto Oncogene A Raf or Proto Oncogene Pks or ARAF or EC

2.7.11.1) – Drug Profiles

INU-152 – Drug Profile

Product Description

Mechanism Of Action

JZP-815 – Drug Profile

Product Description

Mechanism Of Action

History of Events

SJP-601 – Drug Profile

Product Description

Mechanism Of Action

Small Molecule to Inhibit Pan-RAF Kinase for Oncology – Drug Profile

Product Description

Mechanism Of Action

History of Events

Small Molecules to Inhibit RAF for Unspecified Cancer – Drug Profile

Product Description

Mechanism Of Action

tovorafenib – Drug Profile

Product Description

Mechanism Of Action

History of Events

Serine/Threonine Protein Kinase A Raf (Proto Oncogene A Raf or Proto Oncogene Pks or ARAF or EC

2.7.11.1) – Dormant Products

Serine/Threonine Protein Kinase A Raf (Proto Oncogene A Raf or Proto Oncogene Pks or ARAF or EC

2.7.11.1) – Discontinued Products

Serine/Threonine Protein Kinase A Raf (Proto Oncogene A Raf or Proto Oncogene Pks or ARAF or EC

2.7.11.1) – Product Development Milestones

Featured News & Press Releases

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

Table

List of Tables

Number of Products under Development by Stage of Development, 2022

Number of Products under Development by Therapy Areas, 2022

Number of Products under Development by Indication, 2022

Number of Products under Development by Companies, 2022

Products under Development by Companies, 2022

Number of Products under Investigation by Universities/Institutes, 2022

Products under Investigation by Universities/Institutes, 2022

Number of Products by Stage and Mechanism of Actions, 2022

Number of Products by Stage and Route of Administration, 2022

Number of Products by Stage and Molecule Type, 2022

Pipeline by Jazz Pharmaceuticals Plc, 2022

Pipeline by Samjin Pharm Co Ltd, 2022

Pipeline by Takeda Pharmaceutical Co Ltd, 2022

Dormant Projects, 2022

Discontinued Products, 2022

Figures

List of Figures

Number of Products under Development by Stage of Development, 2022

Number of Products under Development by Therapy Areas, 2022

Number of Products under Development by Top 10 Indications, 2022

Number of Products by Stage and Mechanism of Actions, 2022

Number of Products by Stage and Route of Administration, 2022

Number of Products by Stage and Molecule Type, 2022

Frequently asked questions

Serine/Threonine Protein Kinase A Raf (Proto Oncogene A Raf or Proto Oncogene Pks or ARAF or EC 2.7.11.1) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update standard reports
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