Spinal Muscular Atrophy – Forecast in Asia-Pacific Markets to 2028
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Spinal muscular atrophy (SMA) is a rare genetic neurodegenerative disease that primarily affects children. It is characterized by loss of spinal motor neurons, which are specialized cells that control muscle movement.
In recent years the first approved therapy for SMA, Biogen’s Spinraza (nusinersen), has gained marketing authorization in four of the five growth markets (5GM) – Japan, Australia, South Korea and China.
Strong market growth is anticipated across the 5GM over the forecast period. This will largely be driven by increased uptake of Spinraza in the early-to-mid forecast period and the launch of pipeline products from 2020 onwards.
Key unmet environmental and clinical needs in SMA include limited SMA resources and specialists, lack of disease awareness among physicians, low diagnosis rates, limited treatment options and lack of access to disease-modifying therapy for late-onset SMA.
Key Questions Answered
How is SMA currently managed and does this vary by subtype?
To what extent will the launch of pipeline products over the forecast period fulfil the unmet needs in the market?
How will the launch of pipeline products impact Spinraza?
How will growth vary by market?
Scope
Overview of SMA, including epidemiology, etiology, pathophysiology, classification, diagnosis, and disease management.
Market Data including annualized SMA therapeutics market revenue, cost of therapy per patient, and treatment usage patterns in fours patient segments (Type 1, 2, 3, and 4) forecast from 2018 to 2028.
Key topics covered include unmet needs and opportunity assessment, R&D strategies and clinical trial design.
Pipeline analysis: comprehensive data assessing emerging trends and mechanisms of action under development for SMA therapy. The most promising candidates in Phase II and III development are profiled.
Analysis of the current and future market competition in the SMA therapeutics market: Insightful review of the industry drivers and barriers and in-depth analysis of trends within each of the 5GM.
Key Highlights
In the past three years, Spinraza, the first disease-modifying therapy for SMA has been approved in four of the 5GM – Japan, Australia, South Korea and China.
However, the market remains characterized by significant unmet needs, both clinical (e.g. limited treatment options) and environmental (e.g. lack of disease awareness among physicians).
GlobalData anticipates that four pipeline drugs will launch over the forecast period in the Asia-Pacific (APAC) region. These pipeline drugs are expected to address significant unmet needs for SMA and significantly boost growth in the SMA market across the 5GM.
These pipeline products include Novartis’ Zolgensma (onasemnogene abeparvovec-xioi), a gene therapy administered as a one-time intravenous infusion, as well as risdiplam and branaplam, orally administered small molecules in development by Roche and Novartis, respectively, which have a similar mechanism of action to Spinraza.
Across the 5GM, the SMA market is projected to grow from $308.6M in 2018 to $2.5B in 2018 at a CAGR of 23.3%.
Reasons to Buy
The report will enable you to:
Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies most active within the SMA APAC landscape.
Develop business strategies by understanding the trends shaping and driving the SMA APAC market.
Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the SMA APAC market in the future.
Formulate effective sales and marketing strategies by understanding the competitive landscape and by analysing the performance of various competitors.
Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.
AveXis
Biogen
GlaxoSmithKline
Ionis
Kowa Co
Novartis
PTC Therapeutics
Rhone-Poulenc Rorer
Roche
Sanofi
SMA Foundation
Table of Contents
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Frequently asked questions
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