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GlobalData

Pharma

Tremfya positive post-marketing data in COSMOS trial puts drug on path to see net sales of $577m globally for PsA by 2028, says GlobalData

The post-marketing data in the treatment refractory population of the COSMOS Phase IIIb study could allow J&J the opportunity to position interleukin (IL)-23 inhibitor Tremfya early in the PsA treatment algorithm, ahead of the older IL-17 drug class, according to GlobalData. If this happens, and J&J is able to contract aggressively with payers, the leading […]
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Dental devices market to rebound in 2021 as acquisitions rise

The COVID-19 pandemic saw certain markets such as anesthesia and respirator devices grow in 2020, while many others such as dental devices stagnated or saw a huge decline. However, dental devices are projected to make a strong recovery in 2021. The global market value for dental devices in 2021 is estimated to be $20.5bn, up […]
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Interim data from UK study ‘Com-COV’ suggest higher reactogenicity

Preliminary safety results from the Oxford led Phase II Com-COV trial investigating immune responses in patients given heterologous prime-boost vaccine schedules indicate that mixing vaccines leads to higher reactogenicity and more frequent side effects, observes GlobaData, a leading data and analytics company. Nancy Jaser, PharmD/MBA, Pharma Analyst at GlobalData, comments: “The preliminary safety results may […]
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Eli Lilly’s tirzepatide continues to outperform popular diabetes drugs in head-to-head clinical trials, says GlobalData

Eli Lilly’s highly anticipated tirzepatide, a once-weekly dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 receptor agonist (GLP-1RA), recently demonstrated that it was able to not only reduce HbA1c levels in type 2 diabetes (T2D) patients, but also confer weight loss when compared to insulin glargine in the SURPASS-4 trial. Tirzepatide has the potential […]
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COVID-19 puts Cadila Healthcare at the forefront of innovation in India, says GlobalData

Cadila Healthcare Ltd. is among the leading players in India which focuses on bringing in-house developed innovative therapies for patients. Cadila Healthcare has developed a diversified COVID-19 portfolio among the Indian players through in-house development and licensing opportunities. In line with this, the COVID-19 pandemic has put Cadila Healthcare at the forefront of innovation in […]
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Bristol-Myers Squibb’s Mavacamten demonstrates significant improvement of health status for symptomatic oHCM patients in the EXPLORER-HCM trial, says GlobalData

At the 70th annual American College of Cardiology (ACC) 2021 meeting, positive data from the EXPLORE-HCM trial was presented for Bristol-Myers Squibb’s mavacamten, a targeted inhibitor of cardiac-myosin that is currently at the pre-registration stage of development in the US for the treatment of symptomatic obstructive hypertrophic cardiomyopathy (oHCM). According to GlobalData, a leading data […]
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High unmet needs in HNSCC may be partially addressed by clinical development over next decade, says GlobalData

Improved efficacy for HNSCC therapeutics able to demonstrate an overall survival benefit remains a key unmet need in the indication. The next decade may see the introduction of personalized therapy options in locally advanced HNSCC settings along with identification of new druggable targets. Research is being conducted to test therapeutic de-intensification in oropharyngeal carcinoma patients. […]
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Boehringer’s BI 425809 has potential to address cognitive impairment in schizophrenia market, says GlobalData

Boehringer Ingelheim recently announced that its product, BI 425809, has received Breakthrough Therapy Designation (BTD) by the US Food and Drug Administration (FDA) for Cognitive Impairment Associated with Schizophrenia (CIAS). There are currently no approved pharmacological treatments for CIAS and if BI 425809 is successful, it could address this unmet need in the schizophrenia market. […]
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Long-acting growth hormones to account for over 90% of growth hormone deficiency market share across US, Germany, and Japan by 2030, says GlobalData

Rapid uptake of long-acting growth hormones (GH) is set to shake up the growth hormone deficiency (GHD) space in the three major markets (3MM): the US, Germany and Japan. These therapies are projected to capture over 90% of market share in this region by 2030 due to their potential to improve patient convenience and compliance, […]
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ANVS401’s trial hints at promising new approach for early Parkinson’s treatment, says GlobalData

Annovis Bio recently announced positive results from a Phase IIa trial of its pipeline asset ANVS401 (posiphen) in patients with early Parkinson’s disease (PD). The data presented further strengthens the previous interim trial findings, where ANVS401 showed an improvement in the overall motor skill functions of PD patients with no serious adverse events, says GlobalData, […]
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World MS Day: Opportunities remain for products that fulfil significant unmet needs in the MS market, says GlobalData

The multiple sclerosis (MS) therapeutics market is becoming increasingly crowded, but the overall fulfillment of unmet needs is medium. There are no curative therapies for MS, and most existing disease modifying therapies (DMTs) are only partially effective in preventing relapses, with limited impact on the accrual of disability. This means that most patients still experience […]
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