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Following today’s news (29 June) that Merck & Co’s Keytruda received EMA approval for patients with esophageal cancer (EC) or HER2-negative gastroesophageal junction (GEJ) adenocarcinoma with PD-L1 combined positive score (CPS ≥10); Sakis Paliouras, PhD, Senior Oncology & Hematology Analyst at GlobalData, a leading data, and analytics company, offers his view: “When combined with chemotherapy, […]
Teplizumab’s approval will be paradigm changing for T1D as first disease-modifying therapeutic, says GlobalData
The Food and Drug Administration (FDA)’s Endocrinologic and Metabolic Drugs Advisory Committee voted in favor of Provention Bio’s teplizumab 10-7 to delay the onset of type 1 diabetes (T1D). In the eight major markets (8MM*) the number of diagnosed prevalent cases of T1D will grow at an annual growth rate (AGR) of 1.78%, from 3.3 […]
Overactive Bladder market characterized by significant untapped potential, says GlobalData
Untapped potential within the overactive bladder (OAB) market remains considerable due to under-diagnosis and under-treatment of this highly prevalent condition, according to GlobalData, a leading data and analytics company. Key opinion leaders (KOLs) interviewed by GlobalData verified that only a minority of patients with OAB, a symptom complex characterized by urinary urgency, with or without […]
Diagnosed prevalent cases of uveitis to reach 1.9 million by 2029 in the 9MM, says GlobalData
The diagnosed prevalent cases of uveitis in the nine major markets (*9MM) are projected to increase from 1.7 million cases in 2019 to 1.9 million cases in 2029, equating to an annual growth rate (AGR) of 0.97%, according to GlobalData, a leading data and analytics company. GlobalData’s latest report, ‘Uveitis – Epidemiology Forecast to 2029’, […]
Tokyo Olympics could be an epicenter for new COVID-19 infections, says GlobalData
The Tokyo Olympics will likely be an epicenter of transmission for COVID-19 and could increase variant of concern (VOC) spread, bringing new cases to Japan and new cases back to home countries, says GlobalData, a leading data and analytics company. According to GlobalData, there have been over 94 million new cases of COVID-19 in 2021 […]
Rapid-acting Sage Therapeutics and Biogen’s zuranolone could alter way depression is treated, says GlobalData
Sage Therapeutics and Biogen have recently announced positive results from a pivotal Phase III trial for their novel, GABA A receptor allosteric modulator, antidepressant zuranolone. Zuranolone could alter the way major depressive disorder (MDD) is treated with a focus on episodic treatment instead of maintenance treatment, says GlobalData, a leading data and analytics company. Philippa […]
Bio-Thera golimumab biosimilar better positioned to get first to market advantage in China and Europe, says GlobalData
China’s Bio-Thera Solutions has recently initiated a Phase III trial of its proposed golimumab biosimilar BAT2506 in China and Eastern Europe. Against this backdrop, BAT2506 is the first subcutaneous golimumab biosimilar to enter a Phase III trial in multiple countries. It has the potential to be the first golimumab biosimilar to gain approval in China […]
Patient access to gene therapies for cancer set to increase over the next decade, says GlobalData
Gene therapies will provide a valid treatment option for patients that have developed resistance to chemotherapies across several cancer indications. With patient access set to increase over the next decade, these therapies are expected to eliminate the need for further treatments and reduce the cost of disease management, says GlobalData, a leading data and analytics […]
Fabry disease market growth in US and Japan will be driven by entrance of several novel therapies
The Fabry disease (FD) market in the US and Japan will see significant growth between 2020 and 2030, as total sales in these two major markets (2MM) are set to increase from $820.15m in 2020 to $985.81m in 2030, at a compound annual growth rate (CAGR) of 1.9%. This sales growth will be in line […]
China biopharma firms eye partnerships with western counterparts to promote indigenous drugs, says GlobalData
Chinese biopharma companies are eyeing strategic collaborations with western counterparts to leverage their extensive networks and commercial capabilities to promote indigenously developed drugs in China, says GlobalData, a leading data and analytics company. China-based Luye Pharma Group’s holding subsidiary Boan Biotech signed an agreement with AstraZeneca China in May 2021 regarding the promotion rights to […]
Novavax’s COVID-19 vaccine may face severe uptake challenges in the US
Novavax has further demonstrated excellent results from its pivotal PREVENT-19 vaccine trial. Despite this positive data, it will likely see very little uptake in the US, says GlobalData, a leading data and analytics company. Nancy Jaser, PharmD/MBA, Pharma Analyst at GlobalData, comments: “Novavax’s PREVENT-19 trial enrolled close to 30,000 participants across 119 sites in the […]
CARsgen’s novel pipeline therapy could be beneficial to underserved patients in late-stage advanced HCC, says GlobalData
CARsgen Therapeutics’ novel pipeline therapy for advanced hepatocellular carcinoma (HCC) stands out in the American Society of Clinical Oncology (ASCO) virtual annual meeting for being the first-in-class approach with a unique mechanism of action that targets heavily pretreated advanced HCC patients, says GlobalData, a leading data and analytics company. Results for multiple HCC clinical trials […]
New product launches to propel systemic sclerosis market to $1.8bn by 2030
The systemic sclerosis (SSc) market is expected to grow from $498m in 2020 to $1.8bn in 2030 across the seven major markets (7MM*) at a strong compound annual growth rate (CAGR) of 14%, according to GlobalData, a leading data and analytics company. The company’s latest report, ‘Systemic Sclerosis: Global Drug Forecast and Market Analysis to […]
AstraZeneca, Pfizer, Roche lead non-small cell lung cancer digital marketing space in Japan, finds GlobalData
The non-small cell lung cancer (NSCLC) treatment landscape in Japan looks very mature with multiple drugs approved for targeted therapy, immunotherapy and chemotherapy. In this well-established market, several companies are active on digital channels to support NSCLC patients, amongst which AstraZeneca, Pfizer and Roche are the leaders, observes GlobalData, a leading data and analytics company. […]
Latest patent reforms to further bolster innovative pharma research in China, says GlobalData
China has made its latest patent amendments effective from June 01, 2021, reforms which are likely to ensure protection against untimely and unfair generic competition. As a result, the Chinese pharmaceutical market makes itself further competitive and conducive for innovative research companies, both regional and international, says GlobalData, a leading data and analytics company. Although […]
Global oncology Phase II clinical trials heavily impacted by COVID-19 disruptions, says GlobalData
Companies and organizations continue to report clinical trial disruptions across the globe due to the COVID-19 pandemic. These disruptions are being caused by a number of factors including delayed initiation, enrollment suspension, and slow enrollment, according to GlobalData, a leading data and analytics company. GlobalData’s recent global survey of key opinion leaders in the pharma […]
Vaccine and therapeutic COVID-19 clinical trials showcase different trends, says GlobalData
Since COVID-19 was officially declared a pandemic by the World Health Organization (WHO), the peak in total number of clinical trials for the virus was seen in the month of April 2020. However, there has since been a steady decrease in new clinical trial investigations, except for the months of December 2020 and March 2021. […]
RMAT designations predict future directions of cell and gene therapy in oncology
26% of all cell and gene therapies in late-stage development in the US are being developed for oncology. The FDA has backed the use of CAR-T cell therapies for cancer indications. Novel therapeutic approaches indicate a focus on expanding cell and gene therapy for use in solid tumors. Regenerative medicine advanced therapy (RMAT) designations are […]
Dental devices market to rebound in 2021 as acquisitions rise
The COVID-19 pandemic saw certain markets such as anesthesia and respirator devices grow in 2020, while many others such as dental devices stagnated or saw a huge decline. However, dental devices are projected to make a strong recovery in 2021. The global market value for dental devices in 2021 is estimated to be $20.5bn, up […]
Interim data from UK study ‘Com-COV’ suggest higher reactogenicity
Preliminary safety results from the Oxford led Phase II Com-COV trial investigating immune responses in patients given heterologous prime-boost vaccine schedules indicate that mixing vaccines leads to higher reactogenicity and more frequent side effects, observes GlobaData, a leading data and analytics company. Nancy Jaser, PharmD/MBA, Pharma Analyst at GlobalData, comments: “The preliminary safety results may […]