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Following the news that Moderna has announced its COVID-19 vaccine, mRNA-1273, is 94.5% effective in first interim data readout; Michael Breen, PhD, Director of Infectious Diseases and Ophthalmology at GlobalData, a leading data and analytics company, offers his view: “While the efficacy of Moderna’s offering is slightly higher than that reported for Pfizer/BioNTech’s candidate, the […]
Diabetes market continues to evolve rapidly
Across the seven major markets* (7MM), the diagnosed prevalence of type 1 and 2 diabetes (T1D) was approximately 3.7 million and 49.7 million, respectively, in 2020 – according to data and analytics company GlobalData. This is expected to grow to more than 4.3 million by 2025 for Type 1 and 54.4 million for Type 2 […]
Improving clinical trial design could increase drug development for schizophrenia
Following the publication of a review of Phase III clinical trials for drugs for schizophrenia by the FDA, which suggested improvements to clinical trial design; Philippa Salter, Neurology Analyst at GlobalData, a leading data and analytics company, offers her view: “Altering clinical trial design to increase efficiency and reduce costs may encourage developers to pursue […]
COVID-19 has caused 250% surge in special purpose M&A deal volume in biotech space
This year has been a record year for biotech initial public offerings (IPOs), with total deal value already up by 58% compared with all of 2019. The COVID-19 pandemic has also caused a recent surge in special purpose acquisition companies (SPACs) mergers and acquisitions (M&As) as a way of entering the public market compared with […]
Armed with new efficacy and safety data, tenapanor offers opportunity to address two long-standing unmet needs
Ardelyx and Kyowa’s tenapanor therapy for hyperphosphatemia (HP) in chronic kidney disease (CKD) patients who are on dialysis is likely to gain a front-line position in the CKD-HP market due both to its novel mechanism of action (MoA) and its opportunity to address low patient compliance for those on HP monotherapy and the need for […]
Avastin and Tecentriq combination to take over standard of care in hepatocellular carcinoma, says GlobalData
Following the string of approvals this year for Roche’s combination of Avastin (bevacizumab) and Tecentriq (atezolizumab), key opinion leaders interviewed by GlobalData from the five major European pharmaceutical markets (5EU*) and China have noted that the majority of patients would receive Avastin plus Tecentriq in the first-line setting. This offers a major competition to current […]
Pfizer and BioNTech’s final Phase III COVID-19 vaccine analysis could decrease by 10 points from interim 90% data; vaccine could require testing to screen prior infection but rationale still theoretical
With Pfizer and BioNTech announcing that a Phase III trial investigating the BNT162b2 vaccine to be 90% effective in preventing symptomatic COVID-19 in participants without evidence of prior infection; Reynald Castañeda, Pharma Writer for the Investigative News team at GlobalData, offers his view: “The final Phase III efficacy analysis of Pfizer/BioNTech’s COVID-19 vaccine BNT162b2 […]
Key players in breast cancer space engage effectively with Japanese patients through unbranded digital strategies, says GlobalData
In Japan, the breast cancer treatment landscape consists of various systemic therapies including chemotherapy, hormonal therapy, targeted therapy and immunotherapy. Key players in this space provide competitive digital support through branded and unbranded channels. However, patient engagement through unbranded channels to create disease awareness has been more prominent, observes GlobalData, a leading data and analytics […]
Pharma was forced to shuffle technology investment priorities due to COVID-19
COVID-19 has been a wake-up call for pharma companies to rethink their operations and customer access. Embracing digital transformation will have an important role to play in ensuring that the industry overcomes existing and long-term business challenges, seizes opportunities and continues to thrive in challenging business landscape, says GlobalData, a leading data and analytics company. […]
Ease of administration and dual protection can drive novel intranasal vaccine adoption, says GlobalData
Ease of administration and dual protection of local and systemic immunity are promising drivers for intranasal vaccines’ adoption and compliance, particularly at a time when the mammoth task of prospective large scale vaccination is the need of the hour in the wake of the current COVID-19 pandemic, says GlobalData, a leading data and analytics company. […]
While Pfizer and BioNTech’s ‘90% efficacy’ data raises expectations for mRNA vaccines, it will take many more months for key questions to be answered, says GlobalData
Following the news that Pfizer and BioNTech have announced their COVID-19 vaccine is more than 90% effective in first interim data readout; Philipp Rosenbaum, PhD, Senior Infectious Diseases Analyst at GlobalData, a leading data and analytics company, offers his view: “Experts initially assumed that first iterations of a COVID-19 vaccine would show efficacies not much […]
Current global contract manufacturing will not keep up with global COVID-19 vaccine demand
A significant proportion of vaccine developers are smaller companies that lack the capacity and funds to manufacture their vaccines in-house. However, there is also simply not enough contract manufacturing capacity worldwide to cope with commercial COVID-19 vaccine demand, says GlobalData, a leading data and analytics company. Adam Bradbury, PharmSource Analyst at GlobalData, comments: “According to GlobalData’s Service Provider Database, there are 195 contract facilities at 123 companies offering vaccine active pharmaceutical ingredient (API) manufacture. It is difficult to […]
While Pfizer and BioNTech’s ‘90% efficacy’ data raises expectations for mRNA vaccines, it will take many more months for key questions to be answered
Following the news that Pfizer and BioNTech have announced their COVID-19 vaccine is more than 90% effective in first interim data readout; Philipp Rosenbaum, PhD, Senior Infectious Diseases Analyst at GlobalData, a leading data and analytics company, offers his view: “Experts initially assumed that first iterations of a COVID-19 vaccine would show efficacies not much better than common seasonal influenza vaccines, which are usually only 40–60% effective. At a reported 90%, Pfizer and BioNTech’s […]
EU Horizon 2020 research and innovation program invested almost €6M ($7.1M) for COVID-19
In response to the COVID-19 pandemic, Horizon 2020 (H2020), the EU’s biggest research and innovation program, invested almost €6M ($7.1M) for COVID-19 related research and drug development in April 2020. This demonstrates how granting agencies have reacted quickly to prioritizing COVID-19 research, says GlobalData, a leading data and analytics company. Keshalini Sabaratnam, Pharma Analyst at GlobalData, comments: “All […]
Disappointing SOLIDARITY interim results for COVID-19 star remdesivir likely due to trial differences and not drug itself
One of the surprising notes around the interim results of the Phase II/III SOLIDARITY trial for COVID-19 is that remdesivir showed little to no effect. Having shown positive results in previous trials, and being the only drug candidate within the trial to be approved for treatment, it would be expected to show a much stronger […]
Lack of skills and talents poses the biggest challenge to digital transformation in pharmaceutical industry
COVID-19 is set to be a major catalyst for the pharmaceutical industry. The rush to adapt to new social distancing and lockdown norms has led to a hurried digital transformation, leaving many organizations struggling to bridge the digital skills gap, says GlobalData, a leading data and analytics company. GlobalData’s latest report, Digital Transformation and Emerging Technology […]
Industry experts believe Medicare for all is best healthcare plan outcome of US elections
The US currently makes up 38.4% of the global medical device market, according to leading data and analytivs company GlobalData – signifying that adopting Medicare for all will therefore cause a major shift in the industry. When asked ‘What is the best healthcare plan outcome of the US presidential election in November?’, 25% of respondents […]
FDA likely to approve Biogen’s Aducanumab after its review
Following the release of FDA documents today noting support for the safety and efficacy of Biogen’s treatment for Alzheimer’s Disease (AD), aducanumab, it is looking very likely that the drug will become the first new AD therapy to be approved in 17 years. If it is approved, the drug could be in the market by […]
COVID-19 is driving more supplier redundancy
Contract development and manufacturing organizations (CDMOs) are busier than ever, and their work will increase as the pandemic prompts pharma companies to increase redundancy in the supply chain, says GlobalData, a leading data and analytics company. Peter Shapiro, PharmSource Senior Director of Drugs and Business Fundamentals at GlobalData, comments: “Pharma companies may try to reduce […]
Diagnosed prevalent cases of Sjögren’s Syndrome to reach 1.8 million by 2029 in the 7MM
The number of diagnosed prevalent cases of Sjögren’s Syndrome (SS) in the seven major markets (7MM*) is projected to increase from 1.63 million in 2019 to 1.75 million in 2029, with a compound annual growth rate (CAGR) of 0.75%, according to GlobalData, a leading data and analytics company. GlobalData’s latest report, ‘Sjögren’s Syndrome: Epidemiology Forecast to […]