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Following the news that the Phase III study of the COVID-19 vaccine developed by Pfizer and BioNTech has been concluded and is showing 95% efficacy in prevention of the disease; Vinie Varkey, M.Sc, Senior Pharma Analyst at GlobalData, a leading data and analytics company, offers her view: “With the mRNA vaccine candidate BNT162b2 having key safety […]
Pharmaceutical industry continues to bet big on AI
Declining pharmaceutical research and development (R&D) efficiency has been an ongoing problem in pharmaceutical sector. With emerging technologies reshaping various business, pharma is looking to capitalize on artificial intelligence (AI) to streamline operating models and address R&D’s productivity challenges, says GlobalData, a leading data and analytics company. According to a survey as part of GlobalData’s latest report, Digital Transformation and […]
Pfizer’s dependency on JAK inhibitors may cost the company in the long run
While Pfizer has witnessed a positive experience regarding the development of its Janus kinase (JAK) inhibitors, there is the distinct possibility that having so much of its portfolio dependent on JAK inhibitors may cost the company in the long run. A combination of drug class safety concerns, impending patent expiration and the looming threat of […]
Akebia’s vadadustat MACE profile remains unclear and US approval path in non-dialysis CKD anemia uncertain
Akebia Therapeutics presented additional data from its Phase III PRO2TECT trial at the 2020 American Society of Nephrology Kidney Week conference, that evaluated the efficacy and safety of vadadustat versus erythropoiesis stimulating agent (ESA) Aranesp (darbepoetin alfa) for the treatment of chronic kidney disease (CKD) anemia in adult non-dialysis patients. Despite the latest additional data, […]
Low diagnosis rate for COPD negatively affects patients during the COVID-19 pandemic
Today (Wednesday 18 November) is World COPD Day 2020. Chronic obstructive pulmonary disease (COPD) is a group of respiratory diseases that hinder airflow cause breathing difficulties and there is currently no cure. Ana Fernandez Menjivar, Senior Epidemiologist at GlobalData, a leading data and analytics company, offers her view on the current challenges of diagnosing COPD […]
BrainStorm’s NurOwn fails Phase III trial, demonstrating the struggle to develop effective ALS treatment
Following Brainstorm Cell Therapeutics announcement of topline results for its anticipated amyotrophic lateral sclerosis (ALS) stem cell therapy NurOwn; Sarah Elsayed, Neurology Analyst at GlobalData, a leading data and analytics company, offers her view on the opportunities and challenges in this market: “NurOwn is the second pipeline drug to fail a clinical trial for ALS this year, […]
India’s COVID-19 testing strategy will help control future spurt of infection, says GlobalData
Several countries globally are now going through a second wave of COVID-19 infection. India is ranked second in terms of the confirmed COVID-19 cases globally. However, India has drastically ramped up its COVID-19 testing capacity, which will help it control future spurts of infection or future waves, says GlobalData, a leading data analytics and research […]
US, UK and Germany are top manufacturers for COVID-19 vaccines
Vaccine developers are selecting contract manufacturing organizations (CMOs) close to home for their COVID-19 vaccine, as the US, UK and Germany are the most popular supplier locations, says GlobalData, a leading data and analytics company. Johanna Swanson, MBA, Product Manager at GlobalData, comments: “These supply chains contrast with the general trend within the pharma industry to […]
The Italian acromegaly market will more than double in size by 2029, says GlobalData
Marketed therapeutics for the treatment of acromegaly generated sales of at least $33m in Italy in 2019. The value of this market is expected to more than double, surpassing $75m in 2029, according to GlobalData, a leading data and analytics company. GlobalData’s recently published report, ‘Acromegaly and Gigantism: Global Drug Forecast and Market Analysis to 2029’, reveals that the size of the Italian acromegaly market will increase at a 10-year compound annual growth rate (CAGR) of 8.6%. Magdalene Crabbe, Senior Pharmaceutical Analyst at GlobalData, comments: “The Italian market will experience rapid […]
Kala Pharmaceuticals should focus on educating ophthalmologists and having a favorable price point for Eysuvis
The US Food and Drug Administration (FDA) recently announced the approval of Kala Pharmaceuticals’ Eysuvis, a topical steroid (0.25% loteprednol etabonate ophthalmic suspension), for short-term treatment of the signs and symptoms of dry eye syndrome (DES). In order to smoothen market access for this new therapy and facilitate its uptake, Kala Pharmaceuticals will need to […]
COVID-19 vaccine production driving contract service agreements for recombinant vector vaccines
COVID-19 is driving many small pharma companies that do not have the expertise or funds to run their own manufacturing facilities to outsource production. COVID-19 vaccine developers are signing contract service agreements at an unprecedented rate, as pharma companies have publicly revealed 42 contract manufacturing service agreements for 28 unique pipeline COVID-19 vaccines, as manufacturing companies […]
Eli Lilly’s COVID-19 mAb bamlanivimab potential cost effectiveness underscores payer support
Eli Lilly’s monoclonal antibody (mAb) bamlanivimab is unlikely to face payer pushback, despite its broad label, after recent FDA emergency use authorization (EUA) experts told Manasi Vaidya, Pharma Writer for the Investigative News team at GlobalData, a leading data and analytics company. Despite increased scrutiny on drug prices in the COVID-19 era, given the potential […]
Growth of T2D market driven by increasing diagnosed prevalence of disease and emergence of novel pipeline agents
Type 2 diabetes (T2D) is a crowded and competitive landscape, with market growth primarily driven by an increasing diagnosed prevalent population across nine major markets (9MM*) and the emergence of novel pipeline agents, says GlobalData, a leading data and analytics company. The company’s latest report, ‘Type 2 Diabetes: Global Drug Forecast and Market Analysis to 2029’, reveals […]
Moderna and Pfizer raise the bar for COVID-19 vaccines and may ward off competing candidates in development
Following the news that Moderna has announced its COVID-19 vaccine, mRNA-1273, is 94.5% effective in first interim data readout; Michael Breen, PhD, Director of Infectious Diseases and Ophthalmology at GlobalData, a leading data and analytics company, offers his view: “While the efficacy of Moderna’s offering is slightly higher than that reported for Pfizer/BioNTech’s candidate, the […]
Diabetes market continues to evolve rapidly
Across the seven major markets* (7MM), the diagnosed prevalence of type 1 and 2 diabetes (T1D) was approximately 3.7 million and 49.7 million, respectively, in 2020 – according to data and analytics company GlobalData. This is expected to grow to more than 4.3 million by 2025 for Type 1 and 54.4 million for Type 2 […]
Improving clinical trial design could increase drug development for schizophrenia
Following the publication of a review of Phase III clinical trials for drugs for schizophrenia by the FDA, which suggested improvements to clinical trial design; Philippa Salter, Neurology Analyst at GlobalData, a leading data and analytics company, offers her view: “Altering clinical trial design to increase efficiency and reduce costs may encourage developers to pursue […]
Armed with new efficacy and safety data, tenapanor offers opportunity to address two long-standing unmet needs
Ardelyx and Kyowa’s tenapanor therapy for hyperphosphatemia (HP) in chronic kidney disease (CKD) patients who are on dialysis is likely to gain a front-line position in the CKD-HP market due both to its novel mechanism of action (MoA) and its opportunity to address low patient compliance for those on HP monotherapy and the need for […]
COVID-19 has caused 250% surge in special purpose M&A deal volume in biotech space
This year has been a record year for biotech initial public offerings (IPOs), with total deal value already up by 58% compared with all of 2019. The COVID-19 pandemic has also caused a recent surge in special purpose acquisition companies (SPACs) mergers and acquisitions (M&As) as a way of entering the public market compared with […]
Avastin and Tecentriq combination to take over standard of care in hepatocellular carcinoma, says GlobalData
Following the string of approvals this year for Roche’s combination of Avastin (bevacizumab) and Tecentriq (atezolizumab), key opinion leaders interviewed by GlobalData from the five major European pharmaceutical markets (5EU*) and China have noted that the majority of patients would receive Avastin plus Tecentriq in the first-line setting. This offers a major competition to current […]
Key players in breast cancer space engage effectively with Japanese patients through unbranded digital strategies, says GlobalData
In Japan, the breast cancer treatment landscape consists of various systemic therapies including chemotherapy, hormonal therapy, targeted therapy and immunotherapy. Key players in this space provide competitive digital support through branded and unbranded channels. However, patient engagement through unbranded channels to create disease awareness has been more prominent, observes GlobalData, a leading data and analytics […]