Artificial Disc Replacement Systems Pipeline by Stages of Development, Segments, Region, Regulatory Path and Key Companies

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Published: August 08, 2023 Report Code: GDME1595EPD-ST

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Artificial Disc Replacement Systems Pipeline Market Report Overview

Artificial disc replacement offers an alternative to spinal fusion for the patients who have chronic back pain from degenerative disc disease. It allows natural motion in the part of the spine where the disc is implanted and thus allows for an early return to function. The implant is designed so that it can withstand bending, compression and repeated loads during movement.

The artificial disc replacement systems pipeline market research report provides comprehensive information about the artificial disc replacement systems pipeline products with a comparative analysis of the products at various stages of development and information about the clinical trials which are in progress.

Key Segments ·       Lumbar Total Disc Replacement Systems

·       Cervical Total Disc Replacement Systems
Key Territories ·       The US

·       Europe

·       India

·       Brazil

·       China

·       Russia

·       United Kingdom

·       Japan
Key Regulatory Paths ·       PMA

·       CE

·       510(k)

·       ANVISA

·       ICAC

·       NMPA

·       Shonin

·       UKCA
Leading Companies ·       ALCeraX Medizintechnik GmbH

·       Articulus Bio LLC

·       AxioMed Spine Corp

·       Integra Spine

·       Mimesis Spine BV

·       NEXUS TDR Inc
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Artificial Disc Replacement Systems Pipeline Market by Segments

The key segments in the artificial disc replacement systems pipeline market are lumbar total disc replacement systems and cervical total disc replacement systems. As of August 2023, lumbar total disc replacement systems have the highest number of pipeline products.

Artificial Disc Replacement Systems Pipeline Market Analysis by Segments, 2023 (%)

Artificial Disc Replacement Systems Pipeline Market Analysis by Segments, 2023 (%)

For more segment insights into the artificial disc replacement systems pipeline market, download a free report sample

Artificial Disc Replacement Systems Pipeline Market Segmentation by Territories

Some of the key territories in the artificial disc replacement systems market are the United States (US), Europe, India, China, Brazil, Russia, UK, and Japan. As of August 2023, the United States (US) has the highest number of pipeline products.

Artificial Disc Replacement Systems Pipeline Market Analysis by Territories, 2023 (%)

Artificial Disc Replacement Systems Pipeline Market Analysis by Territories, 2023 (%)

For more territory insights into the artificial disc replacement systems pipeline market, download a free report sample

Artificial Disc Replacement Systems Pipeline Market Segmentation by Regulatory Paths

Some of the key regulatory paths in the Artificial disc replacement systems pipeline market are PMA, CE, 510(k), ANVISA, ICAC, NMPA, Shonin, and UKCA. As of August 2023, PMA is the most followed pathway for pipeline products in the market.

Artificial Disc Replacement Systems Pipeline Market Analysis by Regulatory Paths, 2023 (%)

Artificial Disc Replacement Systems Pipeline Market Analysis by Regulatory Paths, 2023 (%)

For more regulatory path insights into the artificial disc replacement systems pipeline market, download a free report sample

Artificial Disc Replacement Systems Pipeline Market – Competitive Landscape

Some of the key companies in the artificial disc replacement systems pipeline market are ALCeraX Medizintechnik GmbH, Articulus Bio LLC, AxioMed Spine Corp, Integra Spine, Mimesis Spine BV, and NEXUS TDR Inc. among others.

AxioMed Spine Corp: AxioMed Spine Corp (AxioMed) is a medical device company that develops spinal disc replacement products for patients with degenerative spine disease. AxioMed also develops spinal implants including early artificial disc development efforts. The company’s Freedom lumbar disc is a disc replacement device, which is used in the treatment of single level symptomatic lumbar degenerative disc disease.

Artificial Disc Replacement Systems Pipeline Market Analysis by Companies, 2023

Artificial Disc Replacement Systems Pipeline Market Analysis by Companies, 2023

For more company insights into the artificial disc replacement systems pipeline market, download a free report sample

Segments Covered in the Report

Artificial Disc Replacement Systems Pipeline Market Segments Outlook

  • Lumbar Total Disc Replacement Systems
  • Cervical Total Disc Replacement Systems

Artificial Disc Replacement Systems Pipeline Market Territories Outlook

  • United States
  • Europe
  • India
  • Brazil
  • China
  • Russia
  • United Kingdom
  • Japan

Artificial Disc Replacement Systems Pipeline Market Regulatory Paths Outlook

  • PMA
  • CE
  • 510(k)
  • ANVISA
  • ICAC
  • NMPA
  • Shonin
  • UKCA

Scope

This report provides:

  • Extensive coverage of the artificial disc replacement systems under development.

  • Details of major pipeline products which includes product description, licensing and collaboration details, and other developmental activities.

  • Reviews of the major players involved in the development of artificial disc replacement systems and lists of all their pipeline projects.

  • Coverage of pipeline products based on various stages of development ranging from early development to approved/issued stage.

  • Key clinical trial data of ongoing trials specific to pipeline products.

  • Recent developments in the segment/industry.

Reasons to Buy

The report enables you to:

  • Formulate significant competitor information, analysis, and insights to improve R&D strategies.

  • Identify emerging players with potentially strong product portfolios and create effective counter strategies to gain a competitive advantage.

  • Identify and understand important and diverse types of Artificial disc replacement systems under development.

  • Develop market-entry and market-expansion strategies.

  • Plan mergers and acquisitions effectively by identifying major players with the most promising pipeline.

  • In-depth analysis of the product’s current stage of development, territory, and estimated launch date

ALCeraX Medizintechnik GmbH
Articulus Bio LLC
AxioMed Spine Corp
C.I. Takiron Corp
City, University of London
Disc Motion Technologies (Inactive)
Integra Spine
Medical University of South Carolina
Meliora Medical BV
MiMedx Group Inc
Mimesis Spine BV
NEXUS TDR Inc
Precision Spine Inc
RE Spine, LLC
SeaSpine, Inc.
SINTX Technologies Inc
Smart Disc Inc
SpinalMotion Inc
Spineart Geneva SA
SpineSmith Holdings LLC
Synergy Disc Replacement, Inc.
TranS1 Inc
TrueMotion Spine, Inc.
University of South Florida
Weill Cornell Medical College
ZimVie Inc

Table of Contents

|1 Table of Contents 3

|1.1 List of Tables 6

|1.2 List of Figures 9

2 Introduction 10

2.1 Artificial Disc Replacement Systems Overview 10

3 Products under Development 11

3.1 Artificial Disc Replacement Systems – Pipeline Products by Stage of Development 11

3.2 Artificial Disc Replacement Systems – Pipeline Products by Segment 12

3.3 Artificial Disc Replacement Systems – Pipeline Products by Territory 13

3.4 Artificial Disc Replacement Systems – Pipeline Products by Regulatory Path 14

3.5 Artificial Disc Replacement Systems – Pipeline Products by Estimated Approval Date 15

3.6 Artificial Disc Replacement Systems – Ongoing Clinical Trials 16

4 Artificial Disc Replacement Systems – Pipeline Products under Development by Companies 17

4.1 Artificial Disc Replacement Systems Companies – Pipeline Products by Stage of Development 17

4.2 Artificial Disc Replacement Systems – Pipeline Products by Stage of Development 19

5 Artificial Disc Replacement Systems Companies and Product Overview 20

5.1 ALCeraX Medizintechnik GmbH Company Overview 20

5.1.1 ALCeraX Medizintechnik GmbH Pipeline Products & Ongoing Clinical Trials Overview 20

5.2 Articulus Bio LLC Company Overview 21

5.2.1 Articulus Bio LLC Pipeline Products & Ongoing Clinical Trials Overview 21

5.3 AxioMed Spine Corp Company Overview 22

5.3.1 AxioMed Spine Corp Pipeline Products & Ongoing Clinical Trials Overview 22

5.4 C.I. Takiron Corp Company Overview 23

5.4.1 C.I. Takiron Corp Pipeline Products & Ongoing Clinical Trials Overview 23

5.5 City, University of London Company Overview 24

5.5.1 City, University of London Pipeline Products & Ongoing Clinical Trials Overview 24

5.6 Disc Motion Technologies (Inactive) Company Overview 25

5.6.1 Disc Motion Technologies (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 25

5.7 Integra Spine Company Overview 26

5.7.1 Integra Spine Pipeline Products & Ongoing Clinical Trials Overview 26

5.8 Medical University of South Carolina Company Overview 27

5.8.1 Medical University of South Carolina Pipeline Products & Ongoing Clinical Trials Overview 27

5.9 Meliora Medical BV Company Overview 28

5.9.1 Meliora Medical BV Pipeline Products & Ongoing Clinical Trials Overview 28

5.10 MiMedx Group Inc Company Overview 30

5.10.1 MiMedx Group Inc Pipeline Products & Ongoing Clinical Trials Overview 30

5.11 Mimesis Spine BV Company Overview 31

5.11.1 Mimesis Spine BV Pipeline Products & Ongoing Clinical Trials Overview 31

5.12 NEXUS TDR Inc Company Overview 32

5.12.1 NEXUS TDR Inc Pipeline Products & Ongoing Clinical Trials Overview 32

5.13 Precision Spine Inc Company Overview 33

5.13.1 Precision Spine Inc Pipeline Products & Ongoing Clinical Trials Overview 33

5.14 RE Spine, LLC Company Overview 34

5.14.1 RE Spine, LLC Pipeline Products & Ongoing Clinical Trials Overview 34

5.15 SeaSpine, Inc. Company Overview 35

5.15.1 SeaSpine, Inc. Pipeline Products & Ongoing Clinical Trials Overview 35

5.16 SINTX Technologies Inc Company Overview 37

5.16.1 SINTX Technologies Inc Pipeline Products & Ongoing Clinical Trials Overview 37

5.17 Smart Disc Inc Company Overview 38

5.17.1 Smart Disc Inc Pipeline Products & Ongoing Clinical Trials Overview 38

5.18 SpinalMotion Inc Company Overview 39

5.18.1 SpinalMotion Inc Pipeline Products & Ongoing Clinical Trials Overview 39

5.19 Spineart Geneva SA Company Overview 40

5.19.1 Spineart Geneva SA Pipeline Products & Ongoing Clinical Trials Overview 40

5.20 SpineSmith Holdings LLC Company Overview 43

5.20.1 SpineSmith Holdings LLC Pipeline Products & Ongoing Clinical Trials Overview 43

5.21 Synergy Disc Replacement, Inc. Company Overview 45

5.21.1 Synergy Disc Replacement, Inc. Pipeline Products & Ongoing Clinical Trials Overview 45

5.22 TranS1 Inc Company Overview 49

5.22.1 TranS1 Inc Pipeline Products & Ongoing Clinical Trials Overview 49

5.23 TrueMotion Spine, Inc. Company Overview 50

5.23.1 TrueMotion Spine, Inc. Pipeline Products & Ongoing Clinical Trials Overview 50

5.24 University of South Florida Company Overview 52

5.24.1 University of South Florida Pipeline Products & Ongoing Clinical Trials Overview 52

5.25 Weill Cornell Medical College Company Overview 53

5.25.1 Weill Cornell Medical College Pipeline Products & Ongoing Clinical Trials Overview 53

5.26 ZimVie Inc Company Overview 54

5.26.1 ZimVie Inc Pipeline Products & Ongoing Clinical Trials Overview 54

6 Artificial Disc Replacement Systems- Recent Developments 57

6.1 May 11, 2023: Medtronic to announce financial results for its fourth quarter and full fiscal year 2023 57

6.2 May 04, 2023: NuVasive announces conference call and webcast of Q1 2023 results 57

6.3 May 02, 2023: MIMEDX announces first quarter 2023 operating and financial results 57

6.4 May 02, 2023: Zimmer Biomet Publishes 2022 Sustainability Report 59

6.5 Apr 26, 2023: Orthofix Medical schedules Q1 earnings release and conference call for May 9, 2023 60

6.6 Apr 12, 2023: Medtronic has a layoff in California 60

6.7 Mar 28, 2023: Stryker announces Annual Meeting of Shareholders 60

6.8 Mar 16, 2023: Surgalign to Host its 2023 Annual Meeting of Shareholders on June 1, 2023 60

6.9 Mar 16, 2023: Medtronic joins in $25M funding round for home monitoring company 60

6.10 Feb 21, 2023: Orthofix Medical Schedules Fourth Quarter Earnings Release and Conference Call for March 6, 2023 61

6.11 Jan 09, 2023: Orthofix Medical Announces Preliminary SeaSpine and Orthofix 2022 Fourth Quarter and Full-Year Net Sales Results 61

6.12 Jan 09, 2023: ATEC Announces Select Preliminary Financial 2022 Results, 2023 Guidance and Closing of Flexible, Non-Dilutive Debt Facility 63

6.13 Jan 09, 2023: MIMEDX Confirms Fourth Quarter and Full Year 2022 Net Sales Expectations, Comments on Evolving Medicare Reimbursement Landscape and Provides Corporate Updates 65

6.14 Jan 04, 2023: Andreas Weller Named Tecomet President & Chief Executive Officer 66

6.15 Jan 03, 2023: MIMEDX Appoints Ricci S. Whitlow as Chief Operating Officer 67

6.16 Dec 08, 2022: MIMEDX Announces Wound & Surgical Product Pipeline Expansion via In-Licensing and Distribution Agreement with Turn Therapeutics 67

6.17 Nov 23, 2022: Medtronic Reports Quarterly Earnings 68

6.18 Nov 22, 2022: Medtronic reports second quarter fiscal 2023 financial results 68

6.19 Nov 15, 2022: Medtronic Set to Announce Earnings on Tuesday 74

6.20 Nov 10, 2022: Surgalign aims to slash $30M from 2023 spending with planned layoffs 74

6.21 Nov 07, 2022: NuVasive launches tube system and excavation micro for posterior spine surgery 74

6.22 Oct 25, 2022: Orthofix Medical Schedules Third Quarter Earnings Release and Conference Call for November 3, 2022 75

6.23 Oct 11, 2022: Orthofix Announces Preliminary Third Quarter and Year-To-Date 2022 Net Sales Results 75

6.24 Oct 10, 2022: ATEC Announces Select Preliminary Third Quarter 2022 Financial Results and Raises Guidance 77

6.25 Oct 06, 2022: Integra LifeSciences appoints Harvinder Singh as Executive Vice President, President Of Co.”s International Business 77

6.26 Oct 06, 2022: Integra LifeSciences Announces Key Executive Appointment 77

6.27 Sep 29, 2022: Artivion AORT Appoints Elizabeth Hoff to its Board 78

6.28 Sep 14, 2022: Orthofix Medical Announces Participation in Upcoming Sidoti Virtual Investor Conference 78

6.29 Sep 12, 2022: Synergy Spine Solutions and Ortho Consulting Group extend strategic partnership to commercialize innovative spine technologies 78

6.30 Sep 12, 2022: NuVasive to Participate as Double Diamond Sponsor at Scoliosis Research Society Annual Meeting 79

6.31 Sep 07, 2022: Medtronic to appear at September investor conferences 79

6.32 Sep 06, 2022: MiMedx Announces Leadership Transition 79

6.33 Aug 30, 2022: ATEC to Participate in Upcoming Investor Conferences 80

6.34 Aug 24, 2022: Artivion to Present at the Gilmartin Group Emerging Growth Company Showcase 81

6.35 Aug 23, 2022: Medtronic reports first quarter fiscal 2023 financial results 81

6.36 Aug 23, 2022: Medtronic Announces Quarterly Earnings Results 83

6.37 Aug 12, 2022: Sintx Technologies Reports Earnings Results for the Second Quarter and Six Months Ended June 30, 2022 86

7 Appendix 88

7.1 Methodology 88

7.2 About GlobalData 91

7.3 Contact Us 91

7.4 Disclaimer 91

Table

Artificial Disc Replacement Systems – Pipeline Products by Stage of Development 11

Artificial Disc Replacement Systems – Pipeline Products by Segment 12

Artificial Disc Replacement Systems – Pipeline Products by Territory 13

Artificial Disc Replacement Systems – Pipeline Products by Regulatory Path 14

Artificial Disc Replacement Systems – Pipeline Products by Estimated Approval Date 15

Artificial Disc Replacement Systems – Ongoing Clinical Trials 16

Artificial Disc Replacement Systems Companies – Pipeline Products by Stage of Development 17

Artificial Disc Replacement Systems – Pipeline Products by Stage of Development 19

ALCeraX Medizintechnik GmbH Pipeline Products & Ongoing Clinical Trials Overview 20

ConCera – Product Status 20

ConCera – Product Description 20

Articulus Bio LLC Pipeline Products & Ongoing Clinical Trials Overview 21

Cervical/Lumbar Spine Artificial Disc – Product Status 21

Cervical/Lumbar Spine Artificial Disc – Product Description 21

AxioMed Spine Corp Pipeline Products & Ongoing Clinical Trials Overview 22

Freedom Lateral Lumbar Disc – Product Status 22

Freedom Lateral Lumbar Disc – Product Description 22

C.I. Takiron Corp Pipeline Products & Ongoing Clinical Trials Overview 23

FABRICUBE – Product Status 23

FABRICUBE – Product Description 23

City, University of London Pipeline Products & Ongoing Clinical Trials Overview 24

Artificial Intervertebral Disc Prosthesis – Product Status 24

Artificial Intervertebral Disc Prosthesis – Product Description 24

Disc Motion Technologies (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 25

Inlign PL – Product Status 25

Inlign PL – Product Description 25

Integra Spine Pipeline Products & Ongoing Clinical Trials Overview 26

eDISC – Product Status 26

eDISC – Product Description 26

Medical University of South Carolina Pipeline Products & Ongoing Clinical Trials Overview 27

Artificial Intervertebral Disc – Product Status 27

Artificial Intervertebral Disc – Product Description 27

Meliora Medical BV Pipeline Products & Ongoing Clinical Trials Overview 28

Mimesis-C – Product Status 28

Mimesis-C – Product Description 28

Prosthetic Intervertebral Disc – Back Pain – Product Status 29

Prosthetic Intervertebral Disc – Back Pain – Product Description 29

MiMedx Group Inc Pipeline Products & Ongoing Clinical Trials Overview 30

SaluDisc – Product Status 30

SaluDisc – Product Description 30

Mimesis Spine BV Pipeline Products & Ongoing Clinical Trials Overview 31

Cervical Total Disc Replacement Device – Product Status 31

Cervical Total Disc Replacement Device – Product Description 31

NEXUS TDR Inc Pipeline Products & Ongoing Clinical Trials Overview 32

FlexBac – Product Status 32

FlexBac – Product Description 32

Precision Spine Inc Pipeline Products & Ongoing Clinical Trials Overview 33

Cervical Disc Replacement Device – Product Status 33

Cervical Disc Replacement Device – Product Description 33

RE Spine, LLC Pipeline Products & Ongoing Clinical Trials Overview 34

Intervertebral Disc – Product Status 34

Intervertebral Disc – Product Description 34

SeaSpine, Inc. Pipeline Products & Ongoing Clinical Trials Overview 35

Catalina – Product Status 35

Catalina – Product Description 35

La Jolla – Product Status 36

La Jolla – Product Description 36

SINTX Technologies Inc Pipeline Products & Ongoing Clinical Trials Overview 37

Spartacus – Product Status 37

Spartacus – Product Description 37

Smart Disc Inc Pipeline Products & Ongoing Clinical Trials Overview 38

Spinal Replacement Disc – Product Status 38

Spinal Replacement Disc – Product Description 38

SpinalMotion Inc Pipeline Products & Ongoing Clinical Trials Overview 39

Kineflex Lumbar Disc – Product Status 39

Kineflex Lumbar Disc – Product Description 39

Spineart Geneva SA Pipeline Products & Ongoing Clinical Trials Overview 40

BAGUERA C Cervical Disc Prosthesis – Product Status 40

BAGUERA C Cervical Disc Prosthesis – Product Description 40

Spineart Geneva SA – Ongoing Clinical Trials Overview 41

BAGUERA C Cervical Disc Prosthesis – A Multicenter, Prospective, Randomized, Clinical Trial Comparing the Safety and Effectiveness of the BAGUERA C Cervical Disc Prosthesis to the Mobi-C Cervical Disc for the Treatment of Patients with Symptomatic Cervical Disc Disease at a Single Level 42

BAGUERA C Cervical Disc Prosthesis – A Multicenter, Prospective, Randomized, Clinical Trial Comparing the Safety and Effectiveness of the BAGUERA C Cervical Disc Prosthesis to the Mobi-C Cervical Disc for the Treatment of Patients with Symptomatic Cervical Disc Disease at Two Contiguous Levels 42

SpineSmith Holdings LLC Pipeline Products & Ongoing Clinical Trials Overview 43

Biologically Active Artificial Disc – Product Status 43

Biologically Active Artificial Disc – Product Description 43

Cervical Disc – Product Status 44

Cervical Disc – Product Description 44

Synergy Disc Replacement, Inc. Pipeline Products & Ongoing Clinical Trials Overview 45

Synergy Disc – Product Status 45

Synergy Disc – Product Description 45

Synergy Disc Replacement, Inc. – Ongoing Clinical Trials Overview 46

Synergy Disc – A Multi-Center Post-Market Data Collection Protocol to Evaluate the Performance of Synergy Spine Solutions Synergy Disc 47

Synergy Disc – A Multi-center, Prospective, Historically Controlled Pivotal Trial Comparing the Safety and Effectiveness of the Synergy Disc to Anterior Cervical Discectomy and Fusion in Patients with One-level Symptomatic Cervical Degenerative Disc Disease (DDD) 47

Synergy Disc – A Multi-Center, Prospective, Historically Controlled Pivotal Trial Comparing the Safety and Effectiveness of the Synergy Disc to Anterior Cervical Discectomy and Fusion in Patients With Two-Level Symptomatic Cervical Degenerative Disc Disease (DDD) 47

Synergy Disc – A Single Site Post-Market Data Collection Protocol to Evaluate the Performance of Synergy Spine Solutions Synergy Disc 48

TranS1 Inc Pipeline Products & Ongoing Clinical Trials Overview 49

TranS1 – Percutaneous Disc Replacement (PDR) – Product Status 49

TranS1 – Percutaneous Disc Replacement (PDR) – Product Description 49

TrueMotion Spine, Inc. Pipeline Products & Ongoing Clinical Trials Overview 50

TrueMotion Cervical D6 – Product Status 50

TrueMotion Cervical D6 – Product Description 50

TrueMotion Lumbar Device – Product Status 51

TrueMotion Lumbar Device – Product Description 51

University of South Florida Pipeline Products & Ongoing Clinical Trials Overview 52

Spine Disc Prosthesis – Product Status 52

Spine Disc Prosthesis – Product Description 52

Weill Cornell Medical College Pipeline Products & Ongoing Clinical Trials Overview 53

Biological Spinal Implant – Product Status 53

Biological Spinal Implant – Product Description 53

ZimVie Inc Pipeline Products & Ongoing Clinical Trials Overview 54

Min T Lumbar Artificial Disc – Product Status 54

Min T Lumbar Artificial Disc – Product Description 54

Next Generation Mobi-C – Product Status 55

Next Generation Mobi-C – Product Description 55

Rescue Cervical Disc – Product Status 55

Rescue Cervical Disc – Product Description 56

Glossary 90

Figures

Artificial Disc Replacement Systems – Pipeline Products by Stage of Development 11

Artificial Disc Replacement Systems – Pipeline Products by Segment 12

Artificial Disc Replacement Systems – Pipeline Products by Territory 13

Artificial Disc Replacement Systems – Pipeline Products by Regulatory Path 14

Artificial Disc Replacement Systems – Pipeline Products by Estimated Approval Date 15

Artificial Disc Replacement Systems – Ongoing Clinical Trials 16

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