1 Table of Contents 3
|1.1 List of Tables 7
|1.2 List of Figures 11
2 Introduction 12
2.1 Synthetic Bone Graft Substitutes Overview 12
3 Products under Development 13
3.1 Synthetic Bone Graft Substitutes – Pipeline Products by Stage of Development 13
3.2 Synthetic Bone Graft Substitutes – Pipeline Products by Territory 14
3.3 Synthetic Bone Graft Substitutes – Pipeline Products by Regulatory Path 15
3.4 Synthetic Bone Graft Substitutes – Pipeline Products by Estimated Approval Date 16
3.5 Synthetic Bone Graft Substitutes – Ongoing Clinical Trials 17
4 Synthetic Bone Graft Substitutes – Pipeline Products under Development by Companies 18
4.1 Synthetic Bone Graft Substitutes Companies – Pipeline Products by Stage of Development 18
4.2 Synthetic Bone Graft Substitutes – Pipeline Products by Stage of Development 20
5 Synthetic Bone Graft Substitutes Companies and Product Overview 22
5.1 Acuitive Technologies Inc Company Overview 22
5.1.1 Acuitive Technologies Inc Pipeline Products & Ongoing Clinical Trials Overview 22
5.2 Agenta Biotechnologies Inc (Inactive) Company Overview 23
5.2.1 Agenta Biotechnologies Inc (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 23
5.3 Amend Surgical, Inc. Company Overview 24
5.3.1 Amend Surgical, Inc. Pipeline Products & Ongoing Clinical Trials Overview 24
5.4 Anika Therapeutics Inc Company Overview 25
5.4.1 Anika Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 25
5.5 Baxter International Inc Company Overview 30
5.5.1 Baxter International Inc Pipeline Products & Ongoing Clinical Trials Overview 30
5.6 Berkeley Advanced Biomaterials Inc Company Overview 31
5.6.1 Berkeley Advanced Biomaterials Inc Pipeline Products & Ongoing Clinical Trials Overview 31
5.7 Bio2 Technologies Inc Company Overview 33
5.7.1 Bio2 Technologies Inc Pipeline Products & Ongoing Clinical Trials Overview 33
5.8 BioGend Therapeutics Co Ltd Company Overview 36
5.8.1 BioGend Therapeutics Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 36
5.9 Biomatlante SA Company Overview 41
5.9.1 Biomatlante SA Pipeline Products & Ongoing Clinical Trials Overview 41
5.10 Biorez Inc Company Overview 42
5.10.1 Biorez Inc Pipeline Products & Ongoing Clinical Trials Overview 42
5.11 BonAlive Biomaterials Ltd. Company Overview 43
5.11.1 BonAlive Biomaterials Ltd. Pipeline Products & Ongoing Clinical Trials Overview 43
5.12 Bone Solutions Inc Company Overview 44
5.12.1 Bone Solutions Inc Pipeline Products & Ongoing Clinical Trials Overview 44
5.13 BoneGrafix, Inc. Company Overview 47
5.13.1 BoneGrafix, Inc. Pipeline Products & Ongoing Clinical Trials Overview 47
5.14 BoneSupport AB Company Overview 48
5.14.1 BoneSupport AB Pipeline Products & Ongoing Clinical Trials Overview 48
5.15 Calcitec, Inc. Company Overview 53
5.15.1 Calcitec, Inc. Pipeline Products & Ongoing Clinical Trials Overview 53
5.16 Daewoong Pharmaceutical Co Ltd Company Overview 54
5.16.1 Daewoong Pharmaceutical Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 54
5.17 Dimension Inx LLC Company Overview 55
5.17.1 Dimension Inx LLC Pipeline Products & Ongoing Clinical Trials Overview 55
5.18 DSM Biomedical BV Company Overview 56
5.18.1 DSM Biomedical BV Pipeline Products & Ongoing Clinical Trials Overview 56
5.19 Elute Inc Company Overview 57
5.19.1 Elute Inc Pipeline Products & Ongoing Clinical Trials Overview 57
5.20 Eskisehir Osmangazi University Company Overview 58
5.20.1 Eskisehir Osmangazi University Pipeline Products & Ongoing Clinical Trials Overview 58
5.21 EternoGen Aesthetics LLC Company Overview 61
5.21.1 EternoGen Aesthetics LLC Pipeline Products & Ongoing Clinical Trials Overview 61
5.22 Graftys SA Company Overview 62
5.22.1 Graftys SA Pipeline Products & Ongoing Clinical Trials Overview 62
5.23 Industrie Biomediche Insubri SA Company Overview 64
5.23.1 Industrie Biomediche Insubri SA Pipeline Products & Ongoing Clinical Trials Overview 64
5.24 Innovoss Inc. (Inactive) Company Overview 65
5.24.1 Innovoss Inc. (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 65
5.25 IRCCS San Raffaele Hospital Company Overview 66
5.25.1 IRCCS San Raffaele Hospital Pipeline Products & Ongoing Clinical Trials Overview 66
5.26 Isto Biologics Company Overview 67
5.26.1 Isto Biologics Pipeline Products & Ongoing Clinical Trials Overview 67
5.27 King’s College London Company Overview 68
5.27.1 King’s College London Pipeline Products & Ongoing Clinical Trials Overview 68
5.28 Maxigen Biotech Inc Company Overview 69
5.28.1 Maxigen Biotech Inc Pipeline Products & Ongoing Clinical Trials Overview 69
5.29 National Center of Innovation for Biomaterials in Orthopaedic Research Company Overview 70
5.29.1 National Center of Innovation for Biomaterials in Orthopaedic Research Pipeline Products & Ongoing Clinical Trials Overview 70
5.30 National University of Science and Technology MiSiS Company Overview 71
5.30.1 National University of Science and Technology MiSiS Pipeline Products & Ongoing Clinical Trials Overview 71
5.31 OrthoMedex LLC Company Overview 72
5.31.1 OrthoMedex LLC Pipeline Products & Ongoing Clinical Trials Overview 72
5.32 PolyPid Ltd Company Overview 73
5.32.1 PolyPid Ltd Pipeline Products & Ongoing Clinical Trials Overview 73
5.33 Polytechnic University of Catalonia Company Overview 74
5.33.1 Polytechnic University of Catalonia Pipeline Products & Ongoing Clinical Trials Overview 74
5.34 Promimic AB Company Overview 75
5.34.1 Promimic AB Pipeline Products & Ongoing Clinical Trials Overview 75
5.35 ReCaPP Company Overview 76
5.35.1 ReCaPP Pipeline Products & Ongoing Clinical Trials Overview 76
5.36 RepRegen Ltd. (Inactive) Company Overview 77
5.36.1 RepRegen Ltd. (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 77
5.37 Revivicor Inc Company Overview 79
5.37.1 Revivicor Inc Pipeline Products & Ongoing Clinical Trials Overview 79
5.38 Sanara MedTech Inc Company Overview 80
5.38.1 Sanara MedTech Inc Pipeline Products & Ongoing Clinical Trials Overview 80
5.39 Scil Technology GmbH Company Overview 81
5.39.1 Scil Technology GmbH Pipeline Products & Ongoing Clinical Trials Overview 81
5.40 SDIP Innovations Pty Ltd Company Overview 82
5.40.1 SDIP Innovations Pty Ltd Pipeline Products & Ongoing Clinical Trials Overview 82
5.41 SIRAKOSS Ltd Company Overview 83
5.41.1 SIRAKOSS Ltd Pipeline Products & Ongoing Clinical Trials Overview 83
5.42 Sofregen Medical Inc Company Overview 86
5.42.1 Sofregen Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 86
5.43 Soteira Inc Company Overview 88
5.43.1 Soteira Inc Pipeline Products & Ongoing Clinical Trials Overview 88
5.44 Sree Chitra Tirunal Institute for Medical Sciences & Technology Company Overview 89
5.44.1 Sree Chitra Tirunal Institute for Medical Sciences & Technology Pipeline Products & Ongoing Clinical Trials Overview 89
5.45 SurGenTec LLC Company Overview 90
5.45.1 SurGenTec LLC Pipeline Products & Ongoing Clinical Trials Overview 90
5.46 University of California San Diego Company Overview 91
5.46.1 University of California San Diego Pipeline Products & Ongoing Clinical Trials Overview 91
5.47 University of Edinburgh Company Overview 92
5.47.1 University of Edinburgh Pipeline Products & Ongoing Clinical Trials Overview 92
5.48 Wright Medical Group NV Company Overview 93
5.48.1 Wright Medical Group NV Pipeline Products & Ongoing Clinical Trials Overview 93
5.49 Xtant Medical Holdings Inc Company Overview 94
5.49.1 Xtant Medical Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview 94
6 Synthetic Bone Graft Substitutes- Recent Developments 95
6.1 Jun 10, 2022: Anika to Participate in the Sidoti Small Cap Virtual Investor Conference 95
6.2 Jun 08, 2022: Baxter to Host Second-Quarter 2022 Financial Results Conference Call for Investors 95
6.3 May 27, 2022: Medtronic reports full year and fourth quarter fiscal year 2022 financial results 95
6.4 May 26, 2022: Medtronic reports full year and fourth quarter fiscal year 2022 financial results announces 8% dividend increase 95
6.5 May 25, 2022: Baxter Highlights Business Strategies and Innovation at 2022 Investor Conference 95
6.6 May 25, 2022: ATEC to Host Investor Day, May 25, 2022 96
6.7 May 19, 2022: ATEC to Participate in Upcoming Investor Events 96
6.8 May 16, 2022: Zimmer Biomet Announces Appointment of New Chief Accounting Officer 96
6.9 May 10, 2022: Baxter to Host 2022 Investor Conference 96
6.10 May 09, 2022: Anika to Participate in the UBS Global Healthcare Conference 2022 97
6.11 May 05, 2022: ATEC Reports First Quarter 2022 Financial Results and Increases Full-Year Revenue Guidance 97
6.12 May 05, 2022: Anika Reports First Quarter Fiscal 2022 Financial Results 98
6.13 May 04, 2022: NuVasive Announces First Quarter 2022 Financial Results 101
6.14 May 03, 2022: Zimmer Biomet Announces First Quarter 2022 Financial Results 103
6.15 Apr 21, 2022: ATEC to Report First Quarter 2022 Financial Results on May 5, 2022 104
6.16 Apr 07, 2022: Anika to Issue First Quarter 2022 Financial Results on Thursday, May 5, 2022 105
6.17 Apr 05, 2022: ATEC to Host Investor Day on May 25, 2022 105
6.18 Apr 04, 2022: Anika to Participate in the 21st Annual Needham Virtual Healthcare Conference 105
6.19 Mar 28, 2022: ATEC to Participate in the Needham Virtual Healthcare Conference 105
6.20 Mar 10, 2022: Anika to Participate in the Canaccord Genuity Musculoskeletal Conference 106
6.21 Mar 08, 2022: Anika Reports Fourth Quarter and Year-End 2021 Financial Results 106
6.22 Mar 01, 2022: Atec Reports Fourth Quarter and Full Year 2021 Financial Results and Recent Corporate Highlights 107
6.23 Feb 22, 2022: Sanara MedTech Announces Unaudited Preliminary Results for the Fourth Quarter and Full Year 2021 108
6.24 Feb 10, 2022: ATEC to Participate in Upcoming Investor Conferences 109
6.25 Feb 10, 2022: Baxter to Present at Citi’s 2022 Virtual Healthcare Conference 109
6.26 Feb 08, 2022: Anika to Issue Fourth Quarter and Year-End 2021 Financial Results on Tuesday, March 8, 2022 109
6.27 Feb 07, 2022: Zimmer Biomet Announces Fourth Quarter and Full-Year 2021 Financial Results 110
6.28 Feb 07, 2022: ATEC to Report Fourth Quarter and Fiscal Year 2021 Financial Results on March 1, 2022 111
6.29 Jan 21, 2022: Zimmer Biomet Announces Filing of Form 10 Registration Statement in Connection with Planned Spinoff of ZimVie; ZimVie to Host Investor Day on February 7 111
6.30 Jan 11, 2022: Integra LifeSciences Reports Preliminary Fourth Quarter and Full-Year 2021 Revenue and Plans $125 Million Share Repurchase 112
6.31 Jan 10, 2022: ATEC Announces Preliminary 2021 Revenue Results and 2022 Guidance 113
6.32 Jan 07, 2022: Collagen Matrix Names Tony Orsini Chief Operating Officer 113
6.33 Jan 06, 2022: ATEC to Participate in the Virtual Needham Growth Conference 114
6.34 Jan 06, 2022: Baxter to Host Fourth-Quarter 2021 Financial Results Conference Call for Investors 114
6.35 Jan 04, 2022: Medtronic Chairman and CEO Geoff Martha to speak at J.P. Morgan healthcare conference 114
6.36 Dec 22, 2021: Sanara MedTech Announces the Retirement of J. Michael Carmena and Appointment of Eric Tanzberger to its Board of Directors 114
6.37 Dec 15, 2021: Sanara MedTech Announces the Appointment of Roszell Mack III to its Board of Directors 115
6.38 Nov 18, 2021: NuVasive to Present at Piper Sandler 33rd Annual Virtual Healthcare Conference 115
6.39 Nov 18, 2021: Zimmer Biomet to Present at Evercore ISI’s 4th Annual HealthCONx Conference 116
6.40 Nov 18, 2021: Anika to Participate in Upcoming Investor Conferences 116
6.41 Nov 09, 2021: NuVasive Announces Third Quarter 2021 Financial Results 116
6.42 Nov 04, 2021: Anika Reports Third Quarter 2021 Financial Results 117
6.43 Nov 03, 2021: Zimmer Biomet to Present at Stifel’s 2021 Virtual Healthcare Conference 120
6.44 Nov 02, 2021: Baxter to Present at Evercore ISI 4th Annual HealthCONx Conference 120
6.45 Nov 01, 2021: ATEC to Participate in Upcoming Investor Conferences 121
6.46 Nov 01, 2021: Anika Appoints Sheryl Conley to Board of Directors 121
6.47 Oct 21, 2021: ATEC to Report Third Quarter Financial Results on November 4, 2021 122
6.48 Oct 18, 2021: Anika to Issue Third Quarter 2021 Financial Results on Thursday, November 4, 2021 122
6.49 Oct 14, 2021: Spineway Announces Increase of 2021 9 months revenue 122
6.50 Oct 13, 2021: Baxter to Present at Credit Suisse 30th Annual Virtual Healthcare Conference 123
6.51 Sep 28, 2021: Globus Medical to Participate in North American Spine Society Annual Meeting 123
6.52 Sep 27, 2021: Baxter to Host Third-Quarter 2021 Financial Results Conference Call for Investors 124
6.53 Sep 13, 2021: SPINEWAY 2021 half-year results 124
6.54 Sep 07, 2021: Anika to Participate in the Morgan Stanley 19th Annual Global Healthcare Conference 125
6.55 Sep 02, 2021: Integra LifeSciences Announces Participation In Upcoming Investor Conferences 126
6.56 Aug 03, 2021: Zimmer Biomet Announces Second Quarter 2021 Financial Results 126
6.57 Aug 03, 2021: Alphatec Reports Second Quarter Financial Results 127
6.58 Jul 29, 2021: Baxter Reports Second-Quarter 2021 Results 128
6.59 Jul 29, 2021: Baxter to Present at UBS Genomics
2.0 and MedTech Innovations Summit 130
6.60 Jul 28, 2021: Integra LifeSciences Reports Second Quarter 2021 Financial Results 131
6.61 Jul 28, 2021: LifeNet Health features revolutionary biologics for wounds at APMA Annual Scientific Meeting 133
6.62 Jul 28, 2021: NuVasive Announces Second Quarter 2021 Financial Results 134
6.63 Jul 27, 2021: Stryker reports second quarter 2021 operating results 137
6.64 Jul 26, 2021: ATEC Appoints Beth Altman to Board of Directors 138
6.65 Jul 19, 2021: Anika to Issue Second Quarter 2021 Financial Results on Thursday, August 5, 2021 139
6.66 Jul 16, 2021: Globus Medical Schedules Second Quarter Earnings Release and Conference Call 139
6.67 Jul 12, 2021: ATEC Announces Select Preliminary Second Quarter 2021 Financial Results 140
6.68 Jul 08, 2021: FDA: Potential biocompatibility concerns with nuvasive specialized orthopedics’ precice devices – letter to health care providers 140
7 Appendix 143
7.1 Methodology 143
7.2 About GlobalData 145
7.3 Contact Us 146
7.4 Disclaimer 146
List of Tables
Synthetic Bone Graft Substitutes – Pipeline Products by Stage of Development 13
Synthetic Bone Graft Substitutes – Pipeline Products by Territory 14
Synthetic Bone Graft Substitutes – Pipeline Products by Regulatory Path 15
Synthetic Bone Graft Substitutes – Pipeline Products by Estimated Approval Date 16
Synthetic Bone Graft Substitutes – Ongoing Clinical Trials 17
Synthetic Bone Graft Substitutes Companies – Pipeline Products by Stage of Development 18
Synthetic Bone Graft Substitutes – Pipeline Products by Stage of Development 20
Acuitive Technologies Inc Pipeline Products & Ongoing Clinical Trials Overview 22
Citrefoam – Product Status 22
Citrefoam – Product Description 22
Agenta Biotechnologies Inc (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 23
B-247 Cranial Bone Graft Implant – Product Status 23
B-247 Cranial Bone Graft Implant – Product Description 23
Amend Surgical, Inc. Pipeline Products & Ongoing Clinical Trials Overview 24
Biomimetic Bone – Product Status 24
Biomimetic Bone – Product Description 24
Anika Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 25
Hyalobone – Product Status 25
Hyalobone – Product Description 25
Hyalofast – Product Status 26
Hyalofast – Product Description 26
Hyalograft C Autograft – Product Status 26
Hyalograft C Autograft – Product Description 27
Anika Therapeutics Inc – Ongoing Clinical Trials Overview 28
Hyalofast – A Prospective, Randomized, Active Treatment-controlled, Evaluator-blinded Multicenter Study to Establish the Superiority of Hyalofast with BMAC in the Treatment of Articular Knee Cartilage Defect Lesions in Comparison to Control 29
Hyalofast – A Study on the Safety and Effectiveness of Improved Microfracture Techniques Using Temperature Sensitive Polymer Hydrogel for Femoral and Cartilage Defects– Prospective, Randomize, Single–center 29
Hyalofast – Cartilage Repair Using a Hyaluronic Acid-based Scaffold with Bone Marrow Aspirate Compared with Microfracture for Focal Articular Cartilage Damage of the Hip: A Randomized Controlled Trial 29
Baxter International Inc Pipeline Products & Ongoing Clinical Trials Overview 30
Synthetic Bone Graft – Spinal – Product Status 30
Synthetic Bone Graft – Spinal – Product Description 30
Berkeley Advanced Biomaterials Inc Pipeline Products & Ongoing Clinical Trials Overview 31
CPA Ceramics – Product Status 31
CPA Ceramics – Product Description 31
HAP Ceramics – Product Status 32
HAP Ceramics – Product Description 32
Bio2 Technologies Inc Pipeline Products & Ongoing Clinical Trials Overview 33
Vitrium – Hammertoe Correction – Product Status 33
Vitrium – Hammertoe Correction – Product Description 33
Vitrium – Radial Osteotomy – Product Status 34
Vitrium – Radial Osteotomy – Product Description 34
Vitrium – Wrist Fracture Revision – Product Status 34
Vitrium – Wrist Fracture Revision – Product Description 35
BioGend Therapeutics Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 36
OIF – Non-Union Bone Fracture – Product Status 36
OIF – Non-Union Bone Fracture – Product Description 36
OIF/ß-TCP – Block Form – Product Status 37
OIF/ß-TCP – Block Form – Product Description 37
OIF/ß-TCP – Granular Form – Product Status 37
OIF/ß-TCP – Granular Form – Product Description 38
BioGend Therapeutics Co Ltd – Ongoing Clinical Trials Overview 39
OIF/ß-TCP – Granular Form – A Randomized, Evaluator-blinded, Controlled Study to Evaluate the Safety and Clinical Performance of OIF/ß-TCP in Patients with Open Tibial Fractures in Need of Bone Grafting 40
Biomatlante SA Pipeline Products & Ongoing Clinical Trials Overview 41
Osteoconductive Resorbable Composite – Product Status 41
Osteoconductive Resorbable Composite – Product Description 41
Biorez Inc Pipeline Products & Ongoing Clinical Trials Overview 42
L-C Ligament – Product Status 42
L-C Ligament – Product Description 42
BonAlive Biomaterials Ltd. Pipeline Products & Ongoing Clinical Trials Overview 43
S53P4 BonAlive Granules – Product Status 43
S53P4 BonAlive Granules – Product Description 43
Bone Solutions Inc Pipeline Products & Ongoing Clinical Trials Overview 44
Osteocrete – Bone Anchor – Product Status 44
Osteocrete – Bone Anchor – Product Description 44
OsteoCrete – Cranial – Product Status 45
OsteoCrete – Cranial – Product Description 45
OsteoCrete – Maxillofacial – Product Status 45
OsteoCrete – Maxillofacial – Product Description 46
OsteoCrete – Non Load Bearing Spine – Product Status 46
OsteoCrete – Non Load Bearing Spine – Product Description 46
BoneGrafix, Inc. Pipeline Products & Ongoing Clinical Trials Overview 47
Solid Bone Block – Product Status 47
Solid Bone Block – Product Description 47
BoneSupport AB Pipeline Products & Ongoing Clinical Trials Overview 48
Cerament + Bisphosphonate – Product Status 48
Cerament + Bisphosphonate – Product Description 48
Cerament|G – Product Status 49
Cerament|G – Product Description 49
Gelatin/Cerament – Product Status 49
Gelatin/Cerament – Product Description 50
BoneSupport AB – Ongoing Clinical Trials Overview 51
Cerament|G – CERAMENTTM|G and V in the Management of Hip and Knee Arthroplasty Revisions (Revision Arthroplasty Italy) 52
Cerament|G – Evaluation of the Efficiency of the Bone Substitute Cerament-G Locally Delivering Gentamicin in the Treatment of Chronic Osteomyelitis of Long Bones: Randomized Multicentre Study in the CRIOAc Network – CONVICTION Study 52
Cerament|G – Two-stage Treatment of Large Bone Defects with Cerament G and Cerament V plus Auto and/or Allograft Using the Masquelet Technique as Salvage Therapy after Bone Resection in Patients with Septic Pseudarthrosis 52
Calcitec, Inc. Pipeline Products & Ongoing Clinical Trials Overview 53
Corticell – Product Status 53
Corticell – Product Description 53
Daewoong Pharmaceutical Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 54
Bongros HA – Product Status 54
Bongros HA – Product Description 54
Dimension Inx LLC Pipeline Products & Ongoing Clinical Trials Overview 55
Hyperelastic Bone – Product Status 55
Hyperelastic Bone – Product Description 55
DSM Biomedical BV Pipeline Products & Ongoing Clinical Trials Overview 56
Structural Synthetic Bone Graft – Product Status 56
Structural Synthetic Bone Graft – Product Description 56
Elute Inc Pipeline Products & Ongoing Clinical Trials Overview 57
EP Granules With Tobramycin – Product Status 57
EP Granules With Tobramycin – Product Description 57
Eskisehir Osmangazi University Pipeline Products & Ongoing Clinical Trials Overview 58
Antimicrobial Synthetic Bone Graft – Product Status 58
Antimicrobial Synthetic Bone Graft – Product Description 58
Eskisehir Osmangazi University – Ongoing Clinical Trials Overview 59
Antimicrobial Synthetic Bone Graft – The Use of Antimicrobial Synthetic Bone Grafts in the Treatment of Bone Infection 60
EternoGen Aesthetics LLC Pipeline Products & Ongoing Clinical Trials Overview 61
Collagen Scaffold – Orthopedic Procedures – Product Status 61
Collagen Scaffold – Orthopedic Procedures – Product Description 61
Graftys SA Pipeline Products & Ongoing Clinical Trials Overview 62
GRFT-M04 – Product Status 62
GRFT-M04 – Product Description 62
GRFT-R02 – Product Status 63
GRFT-R02 – Product Description 63
Industrie Biomediche Insubri SA Pipeline Products & Ongoing Clinical Trials Overview 64
SmartBonePep – Product Status 64
SmartBonePep – Product Description 64
Innovoss Inc. (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 65
Synthetic Bone Material – Product Status 65
Synthetic Bone Material – Product Description 65
IRCCS San Raffaele Hospital Pipeline Products & Ongoing Clinical Trials Overview 66
Tissue Repair Composite Scaffold – Product Status 66
Tissue Repair Composite Scaffold – Product Description 66
Isto Biologics Pipeline Products & Ongoing Clinical Trials Overview 67
InQu Bone Graft Extender And Substitute – Chondral Defects – Product Status 67
InQu Bone Graft Extender And Substitute – Chondral Defects – Product Description 67
King’s College London Pipeline Products & Ongoing Clinical Trials Overview 68
Synthetic Bone Composite – Product Status 68
Synthetic Bone Composite – Product Description 68
Maxigen Biotech Inc Pipeline Products & Ongoing Clinical Trials Overview 69
MaxiSetin – Product Status 69
MaxiSetin – Product Description 69
National Center of Innovation for Biomaterials in Orthopaedic Research Pipeline Products & Ongoing Clinical Trials Overview 70
Composite Bone Graft Substitute – Product Status 70
Composite Bone Graft Substitute – Product Description 70
National University of Science and Technology MiSiS Pipeline Products & Ongoing Clinical Trials Overview 71
Hybrid Bone Implant – Product Status 71
Hybrid Bone Implant – Product Description 71
OrthoMedex LLC Pipeline Products & Ongoing Clinical Trials Overview 72
Cancellous Bone Allograft – Product Status 72
Cancellous Bone Allograft – Product Description 72
PolyPid Ltd Pipeline Products & Ongoing Clinical Trials Overview 73
D-Plex1000 – Product Status 73
D-Plex1000 – Product Description 73
Polytechnic University of Catalonia Pipeline Products & Ongoing Clinical Trials Overview 74
Bone Regeneration Foam – Product Status 74
Bone Regeneration Foam – Product Description 74
Promimic AB Pipeline Products & Ongoing Clinical Trials Overview 75
HAnano Bone – Product Status 75
HAnano Bone – Product Description 75
ReCaPP Pipeline Products & Ongoing Clinical Trials Overview 76
ReCapp Putty – Product Status 76
ReCapp Putty – Product Description 76
RepRegen Ltd. (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 77
Bone Graft Substitute – Load Bearing – Product Status 77
Bone Graft Substitute – Load Bearing – Product Description 77
StronBone-P – Product Status 78
StronBone-P – Product Description 78
Revivicor Inc Pipeline Products & Ongoing Clinical Trials Overview 79
Tendon – ACL Repair – Product Status 79
Tendon – ACL Repair – Product Description 79
Sanara MedTech Inc Pipeline Products & Ongoing Clinical Trials Overview 80
Bone Void Filler – Product Status 80
Bone Void Filler – Product Description 80
Scil Technology GmbH Pipeline Products & Ongoing Clinical Trials Overview 81
ST01 Bone Graft Substitute Material – Product Status 81
ST01 Bone Graft Substitute Material – Product Description 81
SDIP Innovations Pty Ltd Pipeline Products & Ongoing Clinical Trials Overview 82
JAZBI – Product Status 82
JAZBI – Product Description 82
SIRAKOSS Ltd Pipeline Products & Ongoing Clinical Trials Overview 83
MaxSi Graft Granules – Product Status 83
MaxSi Graft Granules – Product Description 83
MaxSi Graft Putty – Product Status 84
MaxSi Graft Putty – Product Description 84
Osteo3 ZP Putty – Product Status 84
Osteo3 ZP Putty – Product Description 85
Sofregen Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 86
SeriACL Scaffold – Product Status 86
SeriACL Scaffold – Product Description 86
SeriCuff Scaffold – Product Status 87
SeriCuff Scaffold – Product Description 87
Soteira Inc Pipeline Products & Ongoing Clinical Trials Overview 88
Nanotechnology Bone Biomaterial – Spinal Repair – Product Status 88
Nanotechnology Bone Biomaterial – Spinal Repair – Product Description 88
Sree Chitra Tirunal Institute for Medical Sciences & Technology Pipeline Products & Ongoing Clinical Trials Overview 89
Bioceramic Cage – Product Status 89
Bioceramic Cage – Product Description 89
SurGenTec LLC Pipeline Products & Ongoing Clinical Trials Overview 90
OsteoFlo NanoPutty-Quadphasic Synthetic Bone Graft – Product Status 90
OsteoFlo NanoPutty-Quadphasic Synthetic Bone Graft – Product Description 90
University of California San Diego Pipeline Products & Ongoing Clinical Trials Overview 91
Synthetic Bone Graft – Product Status 91
Synthetic Bone Graft – Product Description 91
University of Edinburgh Pipeline Products & Ongoing Clinical Trials Overview 92
Shapeable Foam – Bone Repair – Product Status 92
Shapeable Foam – Bone Repair – Product Description 92
Wright Medical Group NV Pipeline Products & Ongoing Clinical Trials Overview 93
Augment Rotator Cuff Graft – Product Status 93
Augment Rotator Cuff Graft – Product Description 93
Xtant Medical Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview 94
Monetite Granules Based Bone Graft – Product Status 94
Monetite Granules Based Bone Graft – Product Description 94
Glossary 145
