Tissue Sealants Pipeline Report including Stages of Development, Segments, Region and Countries, Regulatory Path and Key Companies, 2022 Update

Pages: 122 Published: June 24, 2022 Report Code: GDME1391EPD

The tissue sealant pipeline product market research report provides comprehensive information about the pipeline products with comparative analysis at various stages of development and information about the clinical trials which are in progress. It also gives review details of major pipeline products including product description, licensing and collaboration details, and other developmental activities including pipeline territories, regulatory paths, and estimated approval dates.

Which are the key categories in the tissue sealant pipeline product market?

The key categories in the tissue sealant pipeline product market are Synthetic Tissue Sealants, Fibrin Based Tissue Sealants, Fibrin Based Tissue Sealants in Liquid Form, and Other Protein-Based Tissue Sealants. Synthetic Tissue Sealants has the highest number of pipeline products.

Tissue sealant pipeline product market, by category

Tissue sealant pipeline product market, by category

For more category insights, download a free report sample

Which are the key territories in the tissue sealant pipeline product market?

The key territories in the tissue sealant pipeline product market are the United States, Europe, Israel, Italy, South Korea, the United Kingdom, Brazil, Canada, China, and Japan. The US has the highest number of pipeline products.

Tissue sealant pipeline product market, by territories

Tissue sealant pipeline product market, by territories

For more territory insights, download a free report sample

Which are the key regulatory paths in the tissue sealant pipeline product market?

The key regulatory paths in the tissue sealant pipeline product market are 510(k), PMA, CE, MDITAC, MDL, Ninsho, NMPA, and ANVISA. 510(k) has the highest number of pipeline products.

Tissue sealant pipeline product market, by regulatory path

Tissue sealant pipeline product market, by regulatory path

For more regulatory path insights, download a free report sample

Which are the key companies in the tissue sealant pipeline product market?

The key companies in the tissue sealant pipeline product market are Adhesys Medical GmbH, Advanced Medical Solutions Group plc, Aleo BME Inc, Angiotech Pharmaceuticals Inc, Arch Therapeutics Inc, Arizona State University, Baxter International Inc, Biomedica Management Corp, and Boston University.

Market report overview

Key categories Synthetic Tissue Sealants, Fibrin Based Tissue Sealants, Fibrin Based Tissue Sealants in Liquid Form, and Other Protein-Based Tissue Sealants
Key territories The United States, Europe, Israel, Italy, South Korea, the United Kingdom, Brazil, Canada, China, and Japan
Key regulatory paths 510(k), PMA, CE, MDITAC, MDL, Ninsho, NMPA, and ANVISA
Key companies Adhesys Medical GmbH, Advanced Medical Solutions Group plc, Aleo BME Inc, Angiotech Pharmaceuticals Inc, Arch Therapeutics Inc, Arizona State University, Baxter International Inc, Biomedica Management Corp, and Boston University

 Scope

  • Extensive coverage of the Tissue Sealants under development
  • The report reviews details of major pipeline products which includes, product description, licensing and collaboration details and other developmental activities
  • The report reviews the major players involved in the development of Tissue Sealants and list all their pipeline projects
  • The coverage of pipeline products based on various stages of development ranging from Early Development to Approved / Issued stage
  • The report provides key clinical trial data of ongoing trials specific to pipeline products
  • Recent developments in the segment / industry.

Reasons to Buy

The report enables you to:

  • Formulate significant competitor information, analysis, and insights to improve R&D strategies
  • Identify emerging players with potentially strong product portfolio and create effective counter strategies to gain competitive advantage
  • Identify and understand important and diverse types of Tissue Sealants under development
  • Develop market-entry and market expansion strategies
  • Plan mergers and acquisitions effectively by identifying major players with the most promising pipeline
  • In-depth analysis of the product’s current stage of development, territory and estimated launch date

Key Players

Adhesys Medical GmbH

Advanced Medical Solutions Group plc

Aleo BME Inc

Angiotech Pharmaceuticals Inc

Arch Therapeutics Inc

Arizona State University

Baxter International Inc

Biomedica Management Corp

Boston University

Calmare Therapeutics Inc

Clemson University

Cohera Medical Inc

Covalent Medical, Inc. (Inactive)

CR Bard Inc

DSM Biomedical BV

Eidgenossische Materialprufungs- und Forschungsanstalt

Elastagen Pty Ltd

Ethicon Endo-Surgery Inc

Gamma Therapeutics Inc

GATT Technologies BV

Hemostasis LLC

HyperBranch Medical Technology Inc

Institute of Molecular Biology of Parana

InVivo Therapeutics Corp

Johns Hopkins University

Kollodis BioSciences Inc

Kuros Biosciences AG

Laser Tissue Welding, Inc.

Medisse BV (Inactive)

Meril Life Sciences Pvt Ltd

Nurami Medical Ltd

Pharming Group NV

Polyganics BV

Protein Polymer Technologies Inc (Inactive)

Purdue University

Samyang Biopharmaceuticals Corp

Sealantis Ltd.

Shanghai Haohai Biological Technology Co Ltd

Surgical Sealants, Inc.

Teijin Pharma Ltd

Texas A&M University

The Medicines Co

Tissium SA

University of Akron

Table of Contents

1 Table of Contents 3

|1.1 List of Tables 7

|1.2 List of Figures 11

2 Introduction 12

2.1 Tissue Sealants Overview 12

3 Products under Development 13

3.1 Tissue Sealants – Pipeline Products by Stage of Development 13

3.2 Tissue Sealants – Pipeline Products by Segment 14

3.3 Tissue Sealants – Pipeline Products by Territory 15

3.4 Tissue Sealants – Pipeline Products by Regulatory Path 16

3.5 Tissue Sealants – Pipeline Products by Estimated Approval Date 17

3.6 Tissue Sealants – Ongoing Clinical Trials 18

4 Tissue Sealants – Pipeline Products under Development by Companies 19

4.1 Tissue Sealants Companies – Pipeline Products by Stage of Development 19

4.2 Tissue Sealants – Pipeline Products by Stage of Development 21

5 Tissue Sealants Companies and Product Overview 23

5.1 Adhesys Medical GmbH Company Overview 23

5.1.1 Adhesys Medical GmbH Pipeline Products & Ongoing Clinical Trials Overview 23

5.2 Advanced Medical Solutions Group plc Company Overview 24

5.2.1 Advanced Medical Solutions Group plc Pipeline Products & Ongoing Clinical Trials Overview 24

5.3 Aleo BME Inc Company Overview 25

5.3.1 Aleo BME Inc Pipeline Products & Ongoing Clinical Trials Overview 25

5.4 Angiotech Pharmaceuticals Inc Company Overview 27

5.4.1 Angiotech Pharmaceuticals Inc Pipeline Products & Ongoing Clinical Trials Overview 27

5.5 Arch Therapeutics Inc Company Overview 28

5.5.1 Arch Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 28

5.6 Arizona State University Company Overview 29

5.6.1 Arizona State University Pipeline Products & Ongoing Clinical Trials Overview 29

5.7 Baxter International Inc Company Overview 30

5.7.1 Baxter International Inc Pipeline Products & Ongoing Clinical Trials Overview 30

5.8 Biomedica Management Corp Company Overview 31

5.8.1 Biomedica Management Corp Pipeline Products & Ongoing Clinical Trials Overview 31

5.9 Boston University Company Overview 32

5.9.1 Boston University Pipeline Products & Ongoing Clinical Trials Overview 32

5.10 Calmare Therapeutics Inc Company Overview 33

5.10.1 Calmare Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 33

5.11 Clemson University Company Overview 34

5.11.1 Clemson University Pipeline Products & Ongoing Clinical Trials Overview 34

5.12 Cohera Medical Inc Company Overview 35

5.12.1 Cohera Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 35

5.13 Covalent Medical, Inc. (Inactive) Company Overview 38

5.13.1 Covalent Medical, Inc. (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 38

5.14 CR Bard Inc Company Overview 39

5.14.1 CR Bard Inc Pipeline Products & Ongoing Clinical Trials Overview 39

5.15 Department of Biomedical Engineering Columbia University Company Overview 42

5.15.1 Department of Biomedical Engineering Columbia University Pipeline Products & Ongoing Clinical Trials Overview 42

5.16 DSM Biomedical BV Company Overview 43

5.16.1 DSM Biomedical BV Pipeline Products & Ongoing Clinical Trials Overview 43

5.17 Eidgenossische Materialprufungs- und Forschungsanstalt Company Overview 44

5.17.1 Eidgenossische Materialprufungs- und Forschungsanstalt Pipeline Products & Ongoing Clinical Trials Overview 44

5.18 Elastagen Pty Ltd Company Overview 45

5.18.1 Elastagen Pty Ltd Pipeline Products & Ongoing Clinical Trials Overview 45

5.19 Ethicon Endo-Surgery Inc Company Overview 46

5.19.1 Ethicon Endo-Surgery Inc Pipeline Products & Ongoing Clinical Trials Overview 46

5.20 Gamma Diagnostics Inc Company Overview 47

5.20.1 Gamma Diagnostics Inc Pipeline Products & Ongoing Clinical Trials Overview 47

5.21 GATT Technologies BV Company Overview 48

5.21.1 GATT Technologies BV Pipeline Products & Ongoing Clinical Trials Overview 48

5.22 Hemostasis LLC Company Overview 50

5.22.1 Hemostasis LLC Pipeline Products & Ongoing Clinical Trials Overview 50

5.23 HyperBranch Medical Technology Inc Company Overview 51

5.23.1 HyperBranch Medical Technology Inc Pipeline Products & Ongoing Clinical Trials Overview 51

5.24 Institute of Molecular Biology of Parana Company Overview 53

5.24.1 Institute of Molecular Biology of Parana Pipeline Products & Ongoing Clinical Trials Overview 53

5.25 InVivo Therapeutics Corp Company Overview 54

5.25.1 InVivo Therapeutics Corp Pipeline Products & Ongoing Clinical Trials Overview 54

5.26 Johns Hopkins University Company Overview 55

5.26.1 Johns Hopkins University Pipeline Products & Ongoing Clinical Trials Overview 55

5.27 Kollodis BioSciences Inc Company Overview 56

5.27.1 Kollodis BioSciences Inc Pipeline Products & Ongoing Clinical Trials Overview 56

5.28 Kuros Biosciences AG Company Overview 57

5.28.1 Kuros Biosciences AG Pipeline Products & Ongoing Clinical Trials Overview 57

5.29 Laser Tissue Welding, Inc. Company Overview 59

5.29.1 Laser Tissue Welding, Inc. Pipeline Products & Ongoing Clinical Trials Overview 59

5.30 Medisse BV (Inactive) Company Overview 60

5.30.1 Medisse BV (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 60

5.31 Meril Life Sciences Pvt Ltd Company Overview 61

5.31.1 Meril Life Sciences Pvt Ltd Pipeline Products & Ongoing Clinical Trials Overview 61

5.32 Nurami Medical Ltd Company Overview 62

5.32.1 Nurami Medical Ltd Pipeline Products & Ongoing Clinical Trials Overview 62

5.33 Pharming Group NV Company Overview 63

5.33.1 Pharming Group NV Pipeline Products & Ongoing Clinical Trials Overview 63

5.34 Polyganics BV Company Overview 64

5.34.1 Polyganics BV Pipeline Products & Ongoing Clinical Trials Overview 64

5.35 Protein Polymer Technologies Inc (Inactive) Company Overview 70

5.35.1 Protein Polymer Technologies Inc (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 70

5.36 Purdue University Company Overview 71

5.36.1 Purdue University Pipeline Products & Ongoing Clinical Trials Overview 71

5.37 Samyang Biopharmaceuticals Corp Company Overview 72

5.37.1 Samyang Biopharmaceuticals Corp Pipeline Products & Ongoing Clinical Trials Overview 72

5.38 Sea Run Holdings Inc Company Overview 73

5.38.1 Sea Run Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview 73

5.39 Sealantis Ltd. Company Overview 74

5.39.1 Sealantis Ltd. Pipeline Products & Ongoing Clinical Trials Overview 74

5.40 Shanghai Haohai Biological Technology Co Ltd Company Overview 80

5.40.1 Shanghai Haohai Biological Technology Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 80

5.41 Surgical Sealants, Inc. Company Overview 81

5.41.1 Surgical Sealants, Inc. Pipeline Products & Ongoing Clinical Trials Overview 81

5.42 Teijin Pharma Ltd Company Overview 82

5.42.1 Teijin Pharma Ltd Pipeline Products & Ongoing Clinical Trials Overview 82

5.43 Texas A&M University Company Overview 83

5.43.1 Texas A&M University Pipeline Products & Ongoing Clinical Trials Overview 83

5.44 The Medicines Co Company Overview 85

5.44.1 The Medicines Co Pipeline Products & Ongoing Clinical Trials Overview 85

5.45 Tissium SA Company Overview 86

5.45.1 Tissium SA Pipeline Products & Ongoing Clinical Trials Overview 86

5.46 University of Akron Company Overview 89

5.46.1 University of Akron Pipeline Products & Ongoing Clinical Trials Overview 89

6 Tissue Sealants- Recent Developments 90

6.1 Jun 08, 2022: Baxter to Host Second-Quarter 2022 Financial Results Conference Call for Investors 90

6.2 May 27, 2022: Medtronic reports full year and fourth quarter fiscal year 2022 financial results 90

6.3 May 26, 2022: Medtronic reports full year and fourth quarter fiscal year 2022 financial results announces 8% dividend increase 90

6.4 May 25, 2022: Baxter Highlights Business Strategies and Innovation at 2022 Investor Conference 90

6.5 May 19, 2022: ThermoGenesis Holdings Announces Financial Results for the First Quarter Ended March 31, 2022 and Provides Corporate Update 91

6.6 May 16, 2022: Analysts Anticipate Artivion to Announce $0.09 Earnings Per Share 92

6.7 May 12, 2022: Johnson & Johnson to Participate in Goldman Sachs 43rd Annual Global Healthcare Conference 92

6.8 May 11, 2022: Johnson & Johnson Appoints Thibaut Mongon as CEO Designate of Planned New Consumer Health Company 92

6.9 May 10, 2022: Johnson & Johnson MedTech Adds New CFO to the Mix 93

6.10 May 10, 2022: Baxter to Host 2022 Investor Conference 93

6.11 May 02, 2022: Johnson & Johnson to Participate in the Bernstein 38th Annual Strategic Decisions Conference 93

6.12 Apr 21, 2022: Artivion Announces Release Date and Teleconference Call Details for First Quarter 2022 Financial Results 94

6.13 Apr 20, 2022: Johnson & Johnson to Participate in the UBS Global Healthcare Conference 94

6.14 Apr 19, 2022: Johnson & Johnson Reports Q1 2022 Results 94

6.15 Apr 07, 2022: Johnson & Johnson to Participate in the BofA Securities 2022 Healthcare Conference 95

6.16 Mar 28, 2022: ThermoGenesis Holdings Announces Year End 2021 Financial Results and Provides Corporate Update 95

6.17 Mar 28, 2022: Leading medical device company to build Center for Excellence in Cellular Manufacturing in Greater Sacramento (Rancho Cordova) 97

6.18 Mar 15, 2022: Johnson & Johnson to Host Investor Conference Call on First-Quarter Results 98

6.19 Mar 09, 2022: Artivion to Host Investor & Analyst Day on March 23, 2022 98

6.20 Feb 22, 2022: Asahi Kasai Names Company Veteran as New President 99

6.21 Feb 15, 2022: Johnson & Johnson Names Darius Adamczyk, Chairman and Chief Executive Officer of Honeywell, to its Board of Directors 99

6.22 Feb 10, 2022: Baxter to Present at Citi’s 2022 Virtual Healthcare Conference 99

6.23 Feb 09, 2022: Johnson & Johnson to Participate in the Raymond James 43rd Annual Institutional Investors Conference 99

6.24 Feb 07, 2022: Johnson & Johnson to Participate in the Cowen 42nd Annual Health Care Virtual Conference 100

6.25 Jan 27, 2022: Johnson & Johnson to Participate in Citi’s 2022 Virtual Healthcare Conference 100

6.26 Jan 25, 2022: Johnson & Johnson Reports Q4 and Full-Year 2021 Results 100

6.27 Jan 06, 2022: Baxter to Host Fourth-Quarter 2021 Financial Results Conference Call for Investors 101

6.28 Jan 04, 2022: Medtronic Chairman and CEO Geoff Martha to speak at J.P. Morgan healthcare conference 101

6.29 Dec 10, 2021: Johnson & Johnson to Host Investor Conference Call on Fourth-Quarter Results 101

6.30 Dec 08, 2021: Johnson & Johnson to Participate in the 40th Annual J.P. Morgan Healthcare Conference 102

6.31 Nov 12, 2021: ThermoGenesis Holdings Announces Financial Results for the Third Quarter Ended September 30, 2021, and Provides Corporate Update 102

6.32 Nov 05, 2021: ThermoGenesis Holdings to Announce Financial Results for the Third Quarter Ended September 30, 2021 and Provide a Corporate Strategic Update 103

6.33 Nov 02, 2021: Baxter to Present at Evercore ISI 4th Annual HealthCONx Conference 104

6.34 Oct 13, 2021: Baxter to Present at Credit Suisse 30th Annual Virtual Healthcare Conference 104

6.35 Oct 12, 2021: Dr. Paul Stoffels, Vice Chairman of the Executive Committee and Chief Scientific Officer of Johnson & Johnson To Retire, Effective December 31, 2021 104

6.36 Oct 12, 2021: Johnson & Johnson Announces Jessica Moore as Vice President of Investor Relations 105

6.37 Oct 11, 2021: Johnson & Johnson to Participate in the Credit Suisse 30th Annual Healthcare Conference 106

6.38 Sep 27, 2021: Baxter to Host Third-Quarter 2021 Financial Results Conference Call for Investors 106

6.39 Sep 22, 2021: Anthony Semedo Joins CryoLife Board of Directors 106

6.40 Sep 16, 2021: Johnson & Johnson to Host Investor Conference Call on Third-Quarter Results 107

6.41 Sep 09, 2021: InVivo Therapeutics Announces Participation at Upcoming H.C. Wainwright Annual Global Investment Conference 107

6.42 Aug 19, 2021: Alex Gorsky to Serve as Executive Chairman and Transition Role of Chief Executive Officer of Johnson & Johnson to Joaquin Duato, Effective January 3, 2022 107

6.43 Aug 12, 2021: Johnson & Johnson to Participate in the Morgan Stanley 19th Annual Global Healthcare Conference 110

6.44 Aug 12, 2021: ThermoGenesis Holdings Announces Financial Results for the Second Quarter Ended June 30, 2021, and Provides Corporate Update 110

6.45 Aug 09, 2021: Johnson & Johnson to Participate in Barclays Global Consumer Staples Virtual Conference 111

6.46 Aug 05, 2021: ThermoGenesis Holdings to Announce Financial Results for the Second Quarter Ended June 30, 2021 and Provide a Corporate Strategic Update 112

6.47 Jul 30, 2021: Grifols signs an agreement with ImmunoTek to open 21 plasma centers and further advances on its expansion plan 112

6.48 Jul 29, 2021: Baxter Reports Second-Quarter 2021 Results 113

6.49 Jul 29, 2021: Baxter to Present at UBS Genomics

2.0 and MedTech Innovations Summit 115

6.50 Jul 29, 2021: CryoLife Reports Second Quarter 2021 Financial Results 115

6.51 Jul 27, 2021: Johnson & Johnson to Participate in the Virtual Wells Fargo Healthcare Conference 116

6.52 Jul 21, 2021: Johnson & Johnson Reports 2021 Second-Quarter Results 116

6.53 Jul 15, 2021: CryoLife Announces Release Date and Teleconference Call Details for Second Quarter 2021 Financial Results 117

6.54 Jul 07, 2021: Advanced Medical Solutions Group: Half year trading update 117

6.55 Jun 30, 2021: Asahi Kasei Announces Q1 2021 Financial Results 118

7 Appendix 119

7.1 Methodology 119

7.2 About GlobalData 121

7.3 Contact Us 122

7.4 Disclaimer 122

List of Tables

Tissue Sealants – Pipeline Products by Stage of Development 13

Tissue Sealants – Pipeline Products by Segment 14

Tissue Sealants – Pipeline Products by Territory 15

Tissue Sealants – Pipeline Products by Regulatory Path 16

Tissue Sealants – Pipeline Products by Estimated Approval Date 17

Tissue Sealants – Ongoing Clinical Trials 18

Tissue Sealants Companies – Pipeline Products by Stage of Development 19

Tissue Sealants – Pipeline Products by Stage of Development 21

Adhesys Medical GmbH Pipeline Products & Ongoing Clinical Trials Overview 23

Vivo – Product Status 23

Vivo – Product Description 23

Advanced Medical Solutions Group plc Pipeline Products & Ongoing Clinical Trials Overview 24

Next Generation Internal Fixation And Sealant Device – Product Status 24

Next Generation Internal Fixation And Sealant Device – Product Description 24

Aleo BME Inc Pipeline Products & Ongoing Clinical Trials Overview 25

Dural Sealant – Product Status 25

Dural Sealant – Product Description 25

Surgical Sealant – Product Status 26

Surgical Sealant – Product Description 26

Angiotech Pharmaceuticals Inc Pipeline Products & Ongoing Clinical Trials Overview 27

Hemaseel HMN Fibrin Sealant – Product Status 27

Hemaseel HMN Fibrin Sealant – Product Description 27

Arch Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 28

AC5 Surgery – Sealant – Product Status 28

AC5 Surgery – Sealant – Product Description 28

Arizona State University Pipeline Products & Ongoing Clinical Trials Overview 29

Laser-Activated Nanosealant – Product Status 29

Laser-Activated Nanosealant – Product Description 29

Baxter International Inc Pipeline Products & Ongoing Clinical Trials Overview 30

Tisseel Dura – Product Status 30

Tisseel Dura – Product Description 30

Biomedica Management Corp Pipeline Products & Ongoing Clinical Trials Overview 31

ClotBlock – Product Status 31

ClotBlock – Product Description 31

Boston University Pipeline Products & Ongoing Clinical Trials Overview 32

Hydrogel-Based Aerosolized Sealant Dressing – Product Status 32

Hydrogel-Based Aerosolized Sealant Dressing – Product Description 32

Calmare Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 33

Wound Sealant – Product Status 33

Wound Sealant – Product Description 33

Clemson University Pipeline Products & Ongoing Clinical Trials Overview 34

Surgical Adhesive Hydrogel – Product Status 34

Surgical Adhesive Hydrogel – Product Description 34

Cohera Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 35

Sylys Surgical Sealant – Drug Delivery – Product Status 35

Sylys Surgical Sealant – Drug Delivery – Product Description 35

Sylys Surgical Sealant – Hernia Mesh Fixation – Product Status 36

Sylys Surgical Sealant – Hernia Mesh Fixation – Product Description 36

Sylys Surgical Sealant – Orthopedic – Product Status 36

Sylys Surgical Sealant – Orthopedic – Product Description 37

Covalent Medical, Inc. (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 38

Covabond – Product Status 38

Covabond – Product Description 38

CR Bard Inc Pipeline Products & Ongoing Clinical Trials Overview 39

Progel Dural Sealant – Product Status 39

Progel Dural Sealant – Product Description 39

Progel Emerald – Product Status 40

Progel Emerald – Product Description 40

Tissue Adhesive – Product Status 40

Tissue Adhesive – Product Description 40

Tridyne Peripheral – Product Status 41

Tridyne Peripheral – Product Description 41

Department of Biomedical Engineering Columbia University Pipeline Products & Ongoing Clinical Trials Overview 42

Biomimetic Lung Sealant – Product Status 42

Biomimetic Lung Sealant – Product Description 42

DSM Biomedical BV Pipeline Products & Ongoing Clinical Trials Overview 43

Dural Membrane Sealant – Product Status 43

Dural Membrane Sealant – Product Description 43

Eidgenossische Materialprufungs- und Forschungsanstalt Pipeline Products & Ongoing Clinical Trials Overview 44

Polymer Patch – Product Status 44

Polymer Patch – Product Description 44

Elastagen Pty Ltd Pipeline Products & Ongoing Clinical Trials Overview 45

MeTro – Surgical Glue – Product Status 45

MeTro – Surgical Glue – Product Description 45

Ethicon Endo-Surgery Inc Pipeline Products & Ongoing Clinical Trials Overview 46

Bioseal Next Gen Device – Product Status 46

Bioseal Next Gen Device – Product Description 46

Gamma Diagnostics Inc Pipeline Products & Ongoing Clinical Trials Overview 47

GammaSeal – Product Status 47

GammaSeal – Product Description 47

GATT Technologies BV Pipeline Products & Ongoing Clinical Trials Overview 48

GATT-Spray – Product Status 48

GATT-Spray – Product Description 48

GATT-Tape – Product Status 49

GATT-Tape – Product Description 49

Hemostasis LLC Pipeline Products & Ongoing Clinical Trials Overview 50

Advanced Tissue Sealant – Product Status 50

Advanced Tissue Sealant – Product Description 50

HyperBranch Medical Technology Inc Pipeline Products & Ongoing Clinical Trials Overview 51

Adherus Vascular Sealant – Product Status 51

Adherus Vascular Sealant – Product Description 51

Tissue Plane Sealant – Product Status 52

Tissue Plane Sealant – Product Description 52

Institute of Molecular Biology of Parana Pipeline Products & Ongoing Clinical Trials Overview 53

Recombinant Fibrin Glue – Product Status 53

Recombinant Fibrin Glue – Product Description 53

InVivo Therapeutics Corp Pipeline Products & Ongoing Clinical Trials Overview 54

InVivoSeal – Product Status 54

InVivoSeal – Product Description 54

Johns Hopkins University Pipeline Products & Ongoing Clinical Trials Overview 55

Chondroitin Sulfate-based Adhesive – Product Status 55

Chondroitin Sulfate-based Adhesive – Product Description 55

Kollodis BioSciences Inc Pipeline Products & Ongoing Clinical Trials Overview 56

Hemostat Sealant – Product Status 56

Hemostat Sealant – Product Description 56

Kuros Biosciences AG Pipeline Products & Ongoing Clinical Trials Overview 57

KUR – 211 – Product Status 57

KUR – 211 – Product Description 57

KUR – 212 – Product Status 58

KUR – 212 – Product Description 58

Laser Tissue Welding, Inc. Pipeline Products & Ongoing Clinical Trials Overview 59

Laser Tissue Welding Device – Product Status 59

Laser Tissue Welding Device – Product Description 59

Medisse BV (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 60

PTMC Sealant – Product Status 60

PTMC Sealant – Product Description 60

Meril Life Sciences Pvt Ltd Pipeline Products & Ongoing Clinical Trials Overview 61

PeriTi – Product Status 61

PeriTi – Product Description 61

Nurami Medical Ltd Pipeline Products & Ongoing Clinical Trials Overview 62

ArtiFix – Product Status 62

ArtiFix – Product Description 62

Pharming Group NV Pipeline Products & Ongoing Clinical Trials Overview 63

Recombinant Fibrin Tissue Sealant – Product Status 63

Recombinant Fibrin Tissue Sealant – Product Description 63

Polyganics BV Pipeline Products & Ongoing Clinical Trials Overview 64

ACTISEAL – Product Status 64

ACTISEAL – Product Description 64

ACTISEAL – Adjacent Indications – Product Status 65

ACTISEAL – Adjacent Indications – Product Description 65

LIQOSEAL – Dura Sealing Patch – Product Status 65

LIQOSEAL – Dura Sealing Patch – Product Description 66

LIQOSEAL – Spine Application – Product Status 66

LIQOSEAL – Spine Application – Product Description 66

Polyganics BV – Ongoing Clinical Trials Overview 67

LIQOSEAL – Dura Sealing Patch – Randomized, Two-arm, Multicenter Study to Evaluate the Safety and Efficacy of Dura Sealant Patch in Reducing CSF Leakage Following Elective Cranial Surgery 68

ACTISEAL – Prospective, Multicenter Study to Evaluate the Safety and Performance of a Synthetic Tissue Sealant in Reducing Fluid Leakage Following Elective hepatobiLiary and Pancreatic Surgery 69

Protein Polymer Technologies Inc (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 70

Surgical Tissue Sealant – Product Status 70

Surgical Tissue Sealant – Product Description 70

Purdue University Pipeline Products & Ongoing Clinical Trials Overview 71

Surgical Sealant – Product Status 71

Surgical Sealant – Product Description 71

Samyang Biopharmaceuticals Corp Pipeline Products & Ongoing Clinical Trials Overview 72

Surgical Sealant – Product Status 72

Surgical Sealant – Product Description 72

Sea Run Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview 73

SEA-STAT CNS – Product Status 73

SEA-STAT CNS – Product Description 73

Sealantis Ltd. Pipeline Products & Ongoing Clinical Trials Overview 74

Seal-G – Product Status 74

Seal-G – Product Description 74

Seal-G MIST – Product Status 75

Seal-G MIST – Product Description 75

Sealantis Tissue Adhesive – Product Status 75

Sealantis Tissue Adhesive – Product Description 76

Sealantis Ltd. – Ongoing Clinical Trials Overview 77

Seal-G – Seal-G and Seal-G MIST Study for Reinforcement and Protection of Colonic Anastomoses in Subjects Undergoing Colonic Resection 78

Seal-G MIST – Seal-G and Seal-G MIST Study for Reinforcement and Protection of Colonic Anastomoses in Subjects Undergoing Colonic Resection 79

Shanghai Haohai Biological Technology Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 80

Fibrin Sealant Powder – Product Status 80

Fibrin Sealant Powder – Product Description 80

Surgical Sealants, Inc. Pipeline Products & Ongoing Clinical Trials Overview 81

Thorex – Product Status 81

Thorex – Product Description 81

Teijin Pharma Ltd Pipeline Products & Ongoing Clinical Trials Overview 82

KTF-374 Fibrin Sealant – Product Status 82

KTF-374 Fibrin Sealant – Product Description 82

Texas A&M University Pipeline Products & Ongoing Clinical Trials Overview 83

Tissue Welding Device – Product Status 83

Tissue Welding Device – Product Description 83

Wound Healing And Tissue Repair Bandage – Product Status 84

Wound Healing And Tissue Repair Bandage – Product Description 84

The Medicines Co Pipeline Products & Ongoing Clinical Trials Overview 85

Prevent GI Sealant – Product Status 85

Prevent GI Sealant – Product Description 85

Tissium SA Pipeline Products & Ongoing Clinical Trials Overview 86

SETALUM Sealant – Product Status 86

SETALUM Sealant – Product Description 86

Tissium SA – Ongoing Clinical Trials Overview 87

SETALUM Sealant – Clinical Trial Evaluating the Efficacy of Vascular Sealant 88

University of Akron Pipeline Products & Ongoing Clinical Trials Overview 89

Wound Closure Glue – Product Status 89

Wound Closure Glue – Product Description 89

Glossary 121

List of Figures

Tissue Sealants – Pipeline Products by Stage of Development 13

Tissue Sealants – Pipeline Products by Segment 14

Tissue Sealants – Pipeline Products by Territory 15

Tissue Sealants – Pipeline Products by Regulatory Path 16

Tissue Sealants – Pipeline Products by Estimated Approval Date 17

Tissue Sealants – Ongoing Clinical Trials 18

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