Wound Closure Devices Pipeline by Stages of Development, Segments, Region, Regulatory Path and Key Companies

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Wound Closure Devices Pipeline Market Report Overview

Wound closure devices are used to close wounds that occur due to injuries or surgical procedures. The Wound Closure Devices pipeline market research report provides comprehensive information about the Wound Closure Devices pipeline products with a comparative analysis of the products at various stages of development and information about the clinical trials which are in progress. The report discusses the territories where the Wound Closure Devices pipeline market is present. It also provides names of the regulatory paths followed by the pipeline products and the companies associated with the market.

Key Segments ·       Topical Absorbable Hemostats

·       Tissue Sealants

·       Surgical Adhesion Barriers

·       Tissue Adhesives

·       Synthetic Tissue Sealants

·       Gel Surgical Adhesion Barriers

·       Collagen Based Hemostats

·       Fibrin Based Tissue Sealants

·       Thrombin Based Hemostats

·       Oxidized Regenerated Cellulose Based Hemostats

Key Territories ·       The US

·       Europe

·       South Korea

·       China

·       Japan

·       India

·       Singapore

·       Taiwan

·       Israel

·       Australia

Key Regulatory Paths ·       510(k)

·       CE

·       PMA

·       NMPA

·       MDITAC

·       HAS

·       ICAC

·       BOPA

·       Ninsho

·       TGA

Leading Companies ·       3-D Matrix Europe SAS

·       3-D Matrix Inc

·       3-D Matrix Ltd

·       Abyrx, Inc.

·       ACell Inc

·       Acro Biomedical Co Ltd

·       Actamax Surgical Materials LLC

·       Adhesys Medical GmbH

·       Advanced Biotech Products Pvt Ltd

·       Advanced Medical Solutions Group plc

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Wound Closure Devices Pipeline Market by Segments

Some of the key segments in the Wound Closure Devices market are Topical Absorbable Hemostats, Tissue Sealants, Surgical Adhesion Barriers, Tissue Adhesives, Synthetic Tissue Sealants, Gel Surgical Adhesion Barriers, Collagen Based Hemostats, Fibrin Based Tissue Sealants, Thrombin Based Hemostats, and Oxidized Regenerated Cellulose Based Hemostats. As of July 2023, Topical Absorbable Hemostats has the highest number of pipeline products.

Wound Closure Devices Pipeline Market Analysis by Segments, 2023 (%)

Wound Closure Devices Pipeline Market Analysis by Segments, 2023 (%)

For more segment insights into the Wound Closure Devices pipeline market, download a free report sample

Wound Closure Devices Pipeline Market Segmentation by Territories

Some of the key territories in the Wound Closure Devices pipeline market are the US, Europe, South Korea, China, Japan, India, Singapore, Taiwan, Israel, and Australia. As of July 2023, the US has the highest number of pipeline products.

Wound Closure Devices Pipeline Market Analysis by Territories, 2023 (%)

Wound Closure Devices Pipeline Market Analysis by Territories, 2023 (%)

For more territory insights into the Wound Closure Devices pipeline market, download a free report sample

Wound Closure Devices Pipeline Market Segmentation by Regulatory Paths

Some of the key regulatory paths in the Wound Closure Devices pipeline market are 510(k), CE, PMA, NMPA, MDITAC, HSA, ICAC, BOPA, Ninsho, and TGA. As of July 2023, 510(k) is the most followed pathway for pipeline products in the market.

Wound Closure Devices Pipeline Market Analysis by Regulatory Paths, 2023 (%)

Wound Closure Devices Pipeline Market Analysis by Regulatory Paths, 2023 (%)

For more regulatory path insights into the Wound Closure Devices pipeline market, download a free report sample

Wound Closure Devices Pipeline Market – Competitive Landscape

Some of the key companies in the Wound Closure Devices pipeline market are:

  • 3-D Matrix Europe SAS
  • 3-D Matrix Inc
  • 3-D Matrix Ltd
  • Abyrx, Inc.
  • ACell Inc
  • Acro Biomedical Co Ltd
  • Actamax Surgical Materials LLC
  • Adhesys Medical GmbH
  • Advanced Biotech Products Pvt Ltd
  • Advanced Medical Solutions Group plc

3-D Matrix Europe: It is a medical device company that develops self-assembly peptide technology platform. The company products include PuraStat Dental Bone Void Filler and PuraStat Hemostat. 3-D Matrix is headquartered in Caluire et Cuire, France.

3-D Matrix Inc: It is a specialty biomaterials and medical device company that develops and manufactures peptide biomaterials for clinical applications and life science research. The company has collaborations with various companies for the manufacturing and distribution of its commercial products. 3-D Matrix is headquartered in Newton, Massachusetts, the US.

Leading Wound Closure Devices Companies, 2023

Leading Wound Closure Devices Companies, 2023

For more company insights into the Wound Closure Devices pipeline market, download a free report sample

Segments Covered in the Report

Wound Closure Devices Pipeline Market Segments Outlook

  • Topical Absorbable Hemostats
  • Tissue Sealants
  • Surgical Adhesion Barriers
  • Tissue Adhesives
  • Synthetic Tissue Sealants
  • Gel Surgical Adhesion Barriers
  • Collagen Based Hemostats
  • Fibrin Based Tissue Sealants
  • Thrombin Based Hemostats
  • Oxidized Regenerated Cellulose Based Hemostats

Wound Closure Devices Pipeline Market Territories Outlook

  • The US
  • Europe
  • South Korea
  • China
  • Japan
  • India
  • Singapore
  • Taiwan
  • Israel
  • Australia

Wound Closure Devices Pipeline Market Regulatory Paths Outlook

  • 510(k)
  • CE
  • PMA
  • NMPA
  • MDITAC
  • HAS
  • ICAC
  • BOPA
  • Ninsho
  • TGA

Latest Developments in the Wound Closure Devices Pipeline Market

  • As of July 2023, majority of the pipeline products in the market are in the inactive stage.
  • 3-D Matrix Europe SAS developed NU-MAX (IEIK13) which is a topical peptide hemostatic agent intended for hemorrhage management. It is designed to control oozing bleeding encountered during neurosurgical intracranial procedures and is based on Peptide Technology.
  • 3-D Matrix Inc developed PuraStat – Inflammatory Bowel Disease which is a fully synthetic, transparent, and biodegradable peptide-based surgical hemostat intended for healing wounds in patients with inflammatory bowel disease.

Scope

This report provides:

  • Extensive coverage of the Wound Closure Devices under development.
  • Details of major pipeline products which includes product description, licensing and collaboration details, and other developmental activities.
  • Reviews of the major players involved in the development of Wound Closure Devices and lists of all their pipeline projects.
  • Coverage of pipeline products based on various stages of development ranging from early development to approved/issued stage.
  • Key clinical trial data of ongoing trials specific to pipeline products.
  • Recent developments in the segment/industry.

Reasons to Buy

The report enables you to:

  • Formulate significant competitor information, analysis, and insights to improve R&D strategies
  • Identify emerging players with potentially strong product portfolios and create effective counter strategies to gain a competitive advantage
  • Identify and understand important and diverse types of Wound Closure Devices under development
  • Develop market-entry and market-expansion strategies
  • Plan mergers and acquisitions effectively by identifying major players with the most promising pipeline
  • In-depth analysis of the product’s current stage of development, territory, and estimated launch date

3-D Matrix Europe SAS
3-D Matrix Inc
3-D Matrix Ltd
Abyrx, Inc.
ACell Inc
Acro Biomedical Co Ltd
Actamax Surgical Materials LLC
Adhesys Medical GmbH
Advanced Biotech Products Pvt Ltd
Advanced Medical Solutions Group plc
AFYX Therapeutics A/S
Alafair Biosciences Inc
Albert Ludwigs University of Freiburg
Aleo BME Inc
Alumend LLC
Angiotech Pharmaceuticals Inc
Anika Therapeutics Inc
APRUS Bio-Medical Innovations Pvt Ltd
ARC Medical Devices Inc
Arch Therapeutics Inc
Arizona State University
Artivion Inc
Aura Medsystems, Inc.
BaroStitch
Baxter International Inc
Bayer AG
Bergen Medical Products Inc
Beth Israel Deaconess Medical Center
BioActive Polymers in Lund AB
BioDevek Inc
Biomedica Management Corp
Biom'Up SAS
BNC Korea Co Ltd
Borayer Biotechnology Co Ltd
Boston University
Calmare Therapeutics Inc
CardioCommand Inc
Cellphire Inc
Ceramicos Para Aplicacoes Medicas SA
Clemson University
Cohera Medical Inc
Columbia University
Covalent Medical, Inc. (Inactive)
Covalon Technologies Ltd
Covidien Ltd
CR Bard Inc
Cresilon Inc
Department of Biomedical Engineering Columbia University
DSM Biomedical BV
Duke University
Eidgenossische Materialprufungs- und Forschungsanstalt
Elastagen Pty Ltd
Emory University
Endomedix Inc
Entegrion Inc
Ethicon Endo-Surgery Inc
Ethicon US LLC
ETX Pharma Inc
Fistula Solution Corp
FzioMed Inc
Gamma Diagnostics Inc
GATT Technologies BV
Genzyme Corp
Haemostatix Ltd
Hangzhou Kangji Medical Instrument Co Ltd
Harvard University
Hemostasis LLC
HLL Lifecare Ltd
HydroGlaze BV
HyperBranch Medical Technology Inc
Ichor Sciences LLC
Innocoll Technologies Ltd (Inactive)
Innotherapy Inc
Institute of Molecular Biology of Parana
InVivo Therapeutics Corp
IonMed Ltd.
Jiangxi Boenruier Biotechnology Co Ltd
Jinwoo Bio Co Ltd
Johns Hopkins University
Keratin Biosciences Inc
Kollodis BioSciences Inc
Kuros Biosciences AG
Kytogenics Pharmaceuticals Inc
Lap IQ Inc
Laser Tissue Welding, Inc.
Latch Medical Ltd
Leader Biomedical Europe BV
Lenvitz Medical Solutions Pvt Ltd
Life Care Medical Devices Ltd
Luna Innovations Inc
Magen OrthoMed Ltd
Massachusetts Institute of Technology
Maxigen Biotech Inc
Medcura Inc
Medical Plasmas SL
Medisse BV (Inactive)
Meril Life Sciences Pvt Ltd
MLM Biologics Inc
N8 Medical LLC
Nanyang Technological University
National University of Singapore
Northwestern University
Nurami Medical Ltd
OptMed, Inc.
Paul Scherrer Institute
PetVivo Holdings Inc
Pharming Group NV
Polyganics BV
PolyNovo Biomaterials Pty Ltd
Progress and Health Foundation
Protege Biomedical LLC
Protein Polymer Technologies Inc (Inactive)
Purdue University
Radiation Monitoring Devices Inc
Regenics AS
Resorba GmbH
Rice University
Rutgers The State University of New Jersey
Samyang Biopharmaceuticals Corp
Sanofi Biosurgery Inc
Sea Run Holdings Inc
Sealantis Ltd.
Seikagaku Corp
Selio Medical
Seraffix Ltd
Shanghai Haohai Biological Technology Co Ltd
Sporogenics Pte Ltd
St Teresa Medical Inc
Stanford University
Starling Surgical
STB Lifesaving Technologies
Surgical Energetics LLC
Surgical Sealants, Inc.
Tectum
Teijin Pharma Ltd
Terasaki Institute for Biomedical Innovation
Tetratherix Pty Ltd
Texas A&M Engineering Experiment Station
Texas A&M University
The Medicines Co
TheraCell Inc
Therus Corporation
Thrombotargets Corp
Tissium SA
Toray Medical Co Ltd
Tribos LLC
Tricol Biomedical Inc
Turn Therapeutics Inc
TYBR Health Inc
United Health Products, Inc.
University of Akron
University of Galway
University of Grenoble Alpes
University of Kansas
University of Minnesota
University of North Carolina at Chapel Hill
University of Pennsylvania
University of Toledo
Virginia Commonwealth University
WoundZipper Inc
Xcede Technologies Inc
Xian Huanuo Biotech Co Ltd
Yale University
Yantai Zhenghai Biological Technology Co Ltd
Z-Medica LLC
ZSX Medical LLC

Table of Contents

|1 Table of Contents 3

|1.1 List of Tables 12

|1.2 List of Figures 27

2 Introduction 28

2.1 Wound Closure Devices Overview 28

3 Products under Development 31

3.1 Wound Closure Devices – Pipeline Products by Stage of Development 31

3.2 Wound Closure Devices – Pipeline Products by Segment 32

3.3 Wound Closure Devices – Pipeline Products by Territory 34

3.4 Wound Closure Devices – Pipeline Products by Regulatory Path 36

3.5 Wound Closure Devices – Pipeline Products by Estimated Approval Date 37

3.6 Wound Closure Devices – Ongoing Clinical Trials 38

4 Wound Closure Devices – Pipeline Products under Development by Companies 39

4.1 Wound Closure Devices Companies – Pipeline Products by Stage of Development 39

4.2 Wound Closure Devices – Pipeline Products by Stage of Development 45

5 Wound Closure Devices Companies and Product Overview 52

5.1 3-D Matrix Europe SAS Company Overview 52

5.1.1 3-D Matrix Europe SAS Pipeline Products & Ongoing Clinical Trials Overview 52

5.2 3-D Matrix Inc Company Overview 55

5.2.1 3-D Matrix Inc Pipeline Products & Ongoing Clinical Trials Overview 55

5.3 3-D Matrix Ltd Company Overview 56

5.3.1 3-D Matrix Ltd Pipeline Products & Ongoing Clinical Trials Overview 56

5.4 Abyrx, Inc. Company Overview 62

5.4.1 Abyrx, Inc. Pipeline Products & Ongoing Clinical Trials Overview 62

5.5 ACell Inc Company Overview 63

5.5.1 ACell Inc Pipeline Products & Ongoing Clinical Trials Overview 63

5.6 Acro Biomedical Co Ltd Company Overview 64

5.6.1 Acro Biomedical Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 64

5.7 Actamax Surgical Materials LLC Company Overview 65

5.7.1 Actamax Surgical Materials LLC Pipeline Products & Ongoing Clinical Trials Overview 65

5.8 Adhesys Medical GmbH Company Overview 68

5.8.1 Adhesys Medical GmbH Pipeline Products & Ongoing Clinical Trials Overview 68

5.9 Advanced Biotech Products Pvt Ltd Company Overview 69

5.9.1 Advanced Biotech Products Pvt Ltd Pipeline Products & Ongoing Clinical Trials Overview 69

5.10 Advanced Medical Solutions Group plc Company Overview 70

5.10.1 Advanced Medical Solutions Group plc Pipeline Products & Ongoing Clinical Trials Overview 70

5.11 AFYX Therapeutics A/S Company Overview 75

5.11.1 AFYX Therapeutics A/S Pipeline Products & Ongoing Clinical Trials Overview 75

5.12 Alafair Biosciences Inc Company Overview 76

5.12.1 Alafair Biosciences Inc Pipeline Products & Ongoing Clinical Trials Overview 76

5.13 Albert Ludwigs University of Freiburg Company Overview 77

5.13.1 Albert Ludwigs University of Freiburg Pipeline Products & Ongoing Clinical Trials Overview 77

5.14 Aleo BME Inc Company Overview 78

5.14.1 Aleo BME Inc Pipeline Products & Ongoing Clinical Trials Overview 78

5.15 Alumend LLC Company Overview 81

5.15.1 Alumend LLC Pipeline Products & Ongoing Clinical Trials Overview 81

5.16 Angiotech Pharmaceuticals Inc Company Overview 82

5.16.1 Angiotech Pharmaceuticals Inc Pipeline Products & Ongoing Clinical Trials Overview 82

5.17 Anika Therapeutics Inc Company Overview 84

5.17.1 Anika Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 84

5.18 APRUS Bio-Medical Innovations Pvt Ltd Company Overview 86

5.18.1 APRUS Bio-Medical Innovations Pvt Ltd Pipeline Products & Ongoing Clinical Trials Overview 86

5.19 ARC Medical Devices Inc Company Overview 87

5.19.1 ARC Medical Devices Inc Pipeline Products & Ongoing Clinical Trials Overview 87

5.20 Arch Therapeutics Inc Company Overview 88

5.20.1 Arch Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 88

5.21 Arizona State University Company Overview 98

5.21.1 Arizona State University Pipeline Products & Ongoing Clinical Trials Overview 98

5.22 Artivion Inc Company Overview 99

5.22.1 Artivion Inc Pipeline Products & Ongoing Clinical Trials Overview 99

5.23 Aura Medsystems, Inc. Company Overview 103

5.23.1 Aura Medsystems, Inc. Pipeline Products & Ongoing Clinical Trials Overview 103

5.24 BaroStitch Company Overview 104

5.24.1 BaroStitch Pipeline Products & Ongoing Clinical Trials Overview 104

5.25 Baxter International Inc Company Overview 105

5.25.1 Baxter International Inc Pipeline Products & Ongoing Clinical Trials Overview 105

5.26 Bayer AG Company Overview 108

5.26.1 Bayer AG Pipeline Products & Ongoing Clinical Trials Overview 108

5.27 Bergen Medical Products Inc Company Overview 109

5.27.1 Bergen Medical Products Inc Pipeline Products & Ongoing Clinical Trials Overview 109

5.28 Beth Israel Deaconess Medical Center Company Overview 110

5.28.1 Beth Israel Deaconess Medical Center Pipeline Products & Ongoing Clinical Trials Overview 110

5.29 BioActive Polymers in Lund AB Company Overview 111

5.29.1 BioActive Polymers in Lund AB Pipeline Products & Ongoing Clinical Trials Overview 111

5.30 BioDevek Inc Company Overview 112

5.30.1 BioDevek Inc Pipeline Products & Ongoing Clinical Trials Overview 112

5.31 Biomedica Management Corp Company Overview 113

5.31.1 Biomedica Management Corp Pipeline Products & Ongoing Clinical Trials Overview 113

5.32 Biom’Up SAS Company Overview 116

5.32.1 Biom’Up SAS Pipeline Products & Ongoing Clinical Trials Overview 116

5.33 BNC Korea Co Ltd Company Overview 117

5.33.1 BNC Korea Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 117

5.34 Borayer Biotechnology Co Ltd Company Overview 119

5.34.1 Borayer Biotechnology Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 119

5.35 Boston University Company Overview 120

5.35.1 Boston University Pipeline Products & Ongoing Clinical Trials Overview 120

5.36 Calmare Therapeutics Inc Company Overview 121

5.36.1 Calmare Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 121

5.37 CardioCommand Inc Company Overview 123

5.37.1 CardioCommand Inc Pipeline Products & Ongoing Clinical Trials Overview 123

5.38 Cellphire Inc Company Overview 124

5.38.1 Cellphire Inc Pipeline Products & Ongoing Clinical Trials Overview 124

5.39 Ceramicos Para Aplicacoes Medicas SA Company Overview 126

5.39.1 Ceramicos Para Aplicacoes Medicas SA Pipeline Products & Ongoing Clinical Trials Overview 126

5.40 Clemson University Company Overview 127

5.40.1 Clemson University Pipeline Products & Ongoing Clinical Trials Overview 127

5.41 Cohera Medical Inc Company Overview 128

5.41.1 Cohera Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 128

5.42 Columbia University Company Overview 131

5.42.1 Columbia University Pipeline Products & Ongoing Clinical Trials Overview 131

5.43 Covalent Medical, Inc. (Inactive) Company Overview 132

5.43.1 Covalent Medical, Inc. (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 132

5.44 Covalon Technologies Ltd Company Overview 134

5.44.1 Covalon Technologies Ltd Pipeline Products & Ongoing Clinical Trials Overview 134

5.45 Covidien Ltd Company Overview 136

5.45.1 Covidien Ltd Pipeline Products & Ongoing Clinical Trials Overview 136

5.46 CR Bard Inc Company Overview 137

5.46.1 CR Bard Inc Pipeline Products & Ongoing Clinical Trials Overview 137

5.47 Cresilon Inc Company Overview 142

5.47.1 Cresilon Inc Pipeline Products & Ongoing Clinical Trials Overview 142

5.48 Department of Biomedical Engineering Columbia University Company Overview 143

5.48.1 Department of Biomedical Engineering Columbia University Pipeline Products & Ongoing Clinical Trials Overview 143

5.49 DSM Biomedical BV Company Overview 144

5.49.1 DSM Biomedical BV Pipeline Products & Ongoing Clinical Trials Overview 144

5.50 Duke University Company Overview 145

5.50.1 Duke University Pipeline Products & Ongoing Clinical Trials Overview 145

5.51 Eidgenossische Materialprufungs- und Forschungsanstalt Company Overview 146

5.51.1 Eidgenossische Materialprufungs- und Forschungsanstalt Pipeline Products & Ongoing Clinical Trials Overview 146

5.52 Elastagen Pty Ltd Company Overview 147

5.52.1 Elastagen Pty Ltd Pipeline Products & Ongoing Clinical Trials Overview 147

5.53 Emory University Company Overview 148

5.53.1 Emory University Pipeline Products & Ongoing Clinical Trials Overview 148

5.54 Endomedix Inc Company Overview 149

5.54.1 Endomedix Inc Pipeline Products & Ongoing Clinical Trials Overview 149

5.55 Entegrion Inc Company Overview 151

5.55.1 Entegrion Inc Pipeline Products & Ongoing Clinical Trials Overview 151

5.56 Ethicon Endo-Surgery Inc Company Overview 152

5.56.1 Ethicon Endo-Surgery Inc Pipeline Products & Ongoing Clinical Trials Overview 152

5.57 Ethicon US LLC Company Overview 153

5.57.1 Ethicon US LLC Pipeline Products & Ongoing Clinical Trials Overview 153

5.58 ETX Pharma Inc Company Overview 158

5.58.1 ETX Pharma Inc Pipeline Products & Ongoing Clinical Trials Overview 158

5.59 Fistula Solution Corp Company Overview 159

5.59.1 Fistula Solution Corp Pipeline Products & Ongoing Clinical Trials Overview 159

5.60 FzioMed Inc Company Overview 160

5.60.1 FzioMed Inc Pipeline Products & Ongoing Clinical Trials Overview 160

5.61 Gamma Diagnostics Inc Company Overview 162

5.61.1 Gamma Diagnostics Inc Pipeline Products & Ongoing Clinical Trials Overview 162

5.62 GATT Technologies BV Company Overview 164

5.62.1 GATT Technologies BV Pipeline Products & Ongoing Clinical Trials Overview 164

5.63 Genzyme Corp Company Overview 169

5.63.1 Genzyme Corp Pipeline Products & Ongoing Clinical Trials Overview 169

5.64 Haemostatix Ltd Company Overview 170

5.64.1 Haemostatix Ltd Pipeline Products & Ongoing Clinical Trials Overview 170

5.65 Hangzhou Kangji Medical Instrument Co Ltd Company Overview 172

5.65.1 Hangzhou Kangji Medical Instrument Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 172

5.66 Harvard University Company Overview 173

5.66.1 Harvard University Pipeline Products & Ongoing Clinical Trials Overview 173

5.67 Hemostasis LLC Company Overview 174

5.67.1 Hemostasis LLC Pipeline Products & Ongoing Clinical Trials Overview 174

5.68 HLL Lifecare Ltd Company Overview 179

5.68.1 HLL Lifecare Ltd Pipeline Products & Ongoing Clinical Trials Overview 179

5.69 HydroGlaze BV Company Overview 180

5.69.1 HydroGlaze BV Pipeline Products & Ongoing Clinical Trials Overview 180

5.70 HyperBranch Medical Technology Inc Company Overview 181

5.70.1 HyperBranch Medical Technology Inc Pipeline Products & Ongoing Clinical Trials Overview 181

5.71 Ichor Sciences LLC Company Overview 183

5.71.1 Ichor Sciences LLC Pipeline Products & Ongoing Clinical Trials Overview 183

5.72 Innocoll Technologies Ltd (Inactive) Company Overview 184

5.72.1 Innocoll Technologies Ltd (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 184

5.73 Innotherapy Inc Company Overview 185

5.73.1 Innotherapy Inc Pipeline Products & Ongoing Clinical Trials Overview 185

5.74 Institute of Molecular Biology of Parana Company Overview 187

5.74.1 Institute of Molecular Biology of Parana Pipeline Products & Ongoing Clinical Trials Overview 187

5.75 InVivo Therapeutics Corp Company Overview 188

5.75.1 InVivo Therapeutics Corp Pipeline Products & Ongoing Clinical Trials Overview 188

5.76 IonMed Ltd. Company Overview 189

5.76.1 IonMed Ltd. Pipeline Products & Ongoing Clinical Trials Overview 189

5.77 Jiangxi Boenruier Biotechnology Co Ltd Company Overview 192

5.77.1 Jiangxi Boenruier Biotechnology Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 192

5.78 Jinwoo Bio Co Ltd Company Overview 193

5.78.1 Jinwoo Bio Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 193

5.79 Johns Hopkins University Company Overview 196

5.79.1 Johns Hopkins University Pipeline Products & Ongoing Clinical Trials Overview 196

5.80 Keratin Biosciences Inc Company Overview 197

5.80.1 Keratin Biosciences Inc Pipeline Products & Ongoing Clinical Trials Overview 197

5.81 Kollodis BioSciences Inc Company Overview 198

5.81.1 Kollodis BioSciences Inc Pipeline Products & Ongoing Clinical Trials Overview 198

5.82 Kuros Biosciences AG Company Overview 200

5.82.1 Kuros Biosciences AG Pipeline Products & Ongoing Clinical Trials Overview 200

5.83 Kytogenics Pharmaceuticals Inc Company Overview 202

5.83.1 Kytogenics Pharmaceuticals Inc Pipeline Products & Ongoing Clinical Trials Overview 202

5.84 Lap IQ Inc Company Overview 203

5.84.1 Lap IQ Inc Pipeline Products & Ongoing Clinical Trials Overview 203

5.85 Laser Tissue Welding, Inc. Company Overview 204

5.85.1 Laser Tissue Welding, Inc. Pipeline Products & Ongoing Clinical Trials Overview 204

5.86 Latch Medical Ltd Company Overview 205

5.86.1 Latch Medical Ltd Pipeline Products & Ongoing Clinical Trials Overview 205

5.87 Leader Biomedical Europe BV Company Overview 206

5.87.1 Leader Biomedical Europe BV Pipeline Products & Ongoing Clinical Trials Overview 206

5.88 Lenvitz Medical Solutions Pvt Ltd Company Overview 208

5.88.1 Lenvitz Medical Solutions Pvt Ltd Pipeline Products & Ongoing Clinical Trials Overview 208

5.89 Life Care Medical Devices Ltd Company Overview 209

5.89.1 Life Care Medical Devices Ltd Pipeline Products & Ongoing Clinical Trials Overview 209

5.90 Luna Innovations Inc Company Overview 210

5.90.1 Luna Innovations Inc Pipeline Products & Ongoing Clinical Trials Overview 210

5.91 Magen OrthoMed Ltd Company Overview 212

5.91.1 Magen OrthoMed Ltd Pipeline Products & Ongoing Clinical Trials Overview 212

5.92 Massachusetts Institute of Technology Company Overview 214

5.92.1 Massachusetts Institute of Technology Pipeline Products & Ongoing Clinical Trials Overview 214

5.93 Maxigen Biotech Inc Company Overview 216

5.93.1 Maxigen Biotech Inc Pipeline Products & Ongoing Clinical Trials Overview 216

5.94 Medcura Inc Company Overview 217

5.94.1 Medcura Inc Pipeline Products & Ongoing Clinical Trials Overview 217

5.95 Medical Plasmas SL Company Overview 220

5.95.1 Medical Plasmas SL Pipeline Products & Ongoing Clinical Trials Overview 220

5.96 Medisse BV (Inactive) Company Overview 223

5.96.1 Medisse BV (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 223

5.97 Meril Life Sciences Pvt Ltd Company Overview 226

5.97.1 Meril Life Sciences Pvt Ltd Pipeline Products & Ongoing Clinical Trials Overview 226

5.98 MLM Biologics Inc Company Overview 227

5.98.1 MLM Biologics Inc Pipeline Products & Ongoing Clinical Trials Overview 227

5.99 N8 Medical LLC Company Overview 229

5.99.1 N8 Medical LLC Pipeline Products & Ongoing Clinical Trials Overview 229

5.100 Nanyang Technological University Company Overview 231

5.100.1 Nanyang Technological University Pipeline Products & Ongoing Clinical Trials Overview 231

5.101 National University of Singapore Company Overview 232

5.101.1 National University of Singapore Pipeline Products & Ongoing Clinical Trials Overview 232

5.102 Northwestern University Company Overview 233

5.102.1 Northwestern University Pipeline Products & Ongoing Clinical Trials Overview 233

5.103 Nurami Medical Ltd Company Overview 234

5.103.1 Nurami Medical Ltd Pipeline Products & Ongoing Clinical Trials Overview 234

5.104 OptMed, Inc. Company Overview 235

5.104.1 OptMed, Inc. Pipeline Products & Ongoing Clinical Trials Overview 235

5.105 Paul Scherrer Institute Company Overview 238

5.105.1 Paul Scherrer Institute Pipeline Products & Ongoing Clinical Trials Overview 238

5.106 PetVivo Holdings Inc Company Overview 241

5.106.1 PetVivo Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview 241

5.107 Pharming Group NV Company Overview 242

5.107.1 Pharming Group NV Pipeline Products & Ongoing Clinical Trials Overview 242

5.108 Polyganics BV Company Overview 243

5.108.1 Polyganics BV Pipeline Products & Ongoing Clinical Trials Overview 243

5.109 PolyNovo Biomaterials Pty Ltd Company Overview 249

5.109.1 PolyNovo Biomaterials Pty Ltd Pipeline Products & Ongoing Clinical Trials Overview 249

5.110 Progress and Health Foundation Company Overview 250

5.110.1 Progress and Health Foundation Pipeline Products & Ongoing Clinical Trials Overview 250

5.111 Protege Biomedical LLC Company Overview 251

5.111.1 Protege Biomedical LLC Pipeline Products & Ongoing Clinical Trials Overview 251

5.112 Protein Polymer Technologies Inc (Inactive) Company Overview 252

5.112.1 Protein Polymer Technologies Inc (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 252

5.113 Purdue University Company Overview 253

5.113.1 Purdue University Pipeline Products & Ongoing Clinical Trials Overview 253

5.114 Radiation Monitoring Devices Inc Company Overview 255

5.114.1 Radiation Monitoring Devices Inc Pipeline Products & Ongoing Clinical Trials Overview 255

5.115 Regenics AS Company Overview 256

5.115.1 Regenics AS Pipeline Products & Ongoing Clinical Trials Overview 256

5.116 Resorba GmbH Company Overview 258

5.116.1 Resorba GmbH Pipeline Products & Ongoing Clinical Trials Overview 258

5.117 Rice University Company Overview 260

5.117.1 Rice University Pipeline Products & Ongoing Clinical Trials Overview 260

5.118 Rutgers The State University of New Jersey Company Overview 261

5.118.1 Rutgers The State University of New Jersey Pipeline Products & Ongoing Clinical Trials Overview 261

5.119 Samyang Biopharmaceuticals Corp Company Overview 262

5.119.1 Samyang Biopharmaceuticals Corp Pipeline Products & Ongoing Clinical Trials Overview 262

5.120 Sanofi Biosurgery Inc Company Overview 263

5.120.1 Sanofi Biosurgery Inc Pipeline Products & Ongoing Clinical Trials Overview 263

5.121 Sea Run Holdings Inc Company Overview 265

5.121.1 Sea Run Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview 265

5.122 Sealantis Ltd. Company Overview 267

5.122.1 Sealantis Ltd. Pipeline Products & Ongoing Clinical Trials Overview 267

5.123 Seikagaku Corp Company Overview 273

5.123.1 Seikagaku Corp Pipeline Products & Ongoing Clinical Trials Overview 273

5.124 Selio Medical Company Overview 276

5.124.1 Selio Medical Pipeline Products & Ongoing Clinical Trials Overview 276

5.125 Seraffix Ltd Company Overview 277

5.125.1 Seraffix Ltd Pipeline Products & Ongoing Clinical Trials Overview 277

5.126 Shanghai Haohai Biological Technology Co Ltd Company Overview 278

5.126.1 Shanghai Haohai Biological Technology Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 278

5.127 Sporogenics Pte Ltd Company Overview 279

5.127.1 Sporogenics Pte Ltd Pipeline Products & Ongoing Clinical Trials Overview 279

5.128 St Teresa Medical Inc Company Overview 280

5.128.1 St Teresa Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 280

5.129 Stanford University Company Overview 281

5.129.1 Stanford University Pipeline Products & Ongoing Clinical Trials Overview 281

5.130 Starling Surgical Company Overview 283

5.130.1 Starling Surgical Pipeline Products & Ongoing Clinical Trials Overview 283

5.131 STB Lifesaving Technologies Company Overview 284

5.131.1 STB Lifesaving Technologies Pipeline Products & Ongoing Clinical Trials Overview 284

5.132 Surgical Energetics LLC Company Overview 285

5.132.1 Surgical Energetics LLC Pipeline Products & Ongoing Clinical Trials Overview 285

5.133 Surgical Sealants, Inc. Company Overview 286

5.133.1 Surgical Sealants, Inc. Pipeline Products & Ongoing Clinical Trials Overview 286

5.134 Tectum Company Overview 287

5.134.1 Tectum Pipeline Products & Ongoing Clinical Trials Overview 287

5.135 Teijin Pharma Ltd Company Overview 289

5.135.1 Teijin Pharma Ltd Pipeline Products & Ongoing Clinical Trials Overview 289

5.136 Terasaki Institute for Biomedical Innovation Company Overview 290

5.136.1 Terasaki Institute for Biomedical Innovation Pipeline Products & Ongoing Clinical Trials Overview 290

5.137 Tetratherix Pty Ltd Company Overview 291

5.137.1 Tetratherix Pty Ltd Pipeline Products & Ongoing Clinical Trials Overview 291

5.138 Texas A&M Engineering Experiment Station Company Overview 292

5.138.1 Texas A&M Engineering Experiment Station Pipeline Products & Ongoing Clinical Trials Overview 292

5.139 Texas A&M University Company Overview 293

5.139.1 Texas A&M University Pipeline Products & Ongoing Clinical Trials Overview 293

5.140 The Medicines Co Company Overview 295

5.140.1 The Medicines Co Pipeline Products & Ongoing Clinical Trials Overview 295

5.141 TheraCell Inc Company Overview 297

5.141.1 TheraCell Inc Pipeline Products & Ongoing Clinical Trials Overview 297

5.142 Therus Corporation Company Overview 298

5.142.1 Therus Corporation Pipeline Products & Ongoing Clinical Trials Overview 298

5.143 Thrombotargets Corp Company Overview 299

5.143.1 Thrombotargets Corp Pipeline Products & Ongoing Clinical Trials Overview 299

5.144 Tissium SA Company Overview 303

5.144.1 Tissium SA Pipeline Products & Ongoing Clinical Trials Overview 303

5.145 Toray Medical Co Ltd Company Overview 310

5.145.1 Toray Medical Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 310

5.146 Tribos LLC Company Overview 311

5.146.1 Tribos LLC Pipeline Products & Ongoing Clinical Trials Overview 311

5.147 Tricol Biomedical Inc Company Overview 312

5.147.1 Tricol Biomedical Inc Pipeline Products & Ongoing Clinical Trials Overview 312

5.148 Turn Therapeutics Inc Company Overview 313

5.148.1 Turn Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 313

5.149 TYBR Health Inc Company Overview 314

5.149.1 TYBR Health Inc Pipeline Products & Ongoing Clinical Trials Overview 314

5.150 United Health Products, Inc. Company Overview 315

5.150.1 United Health Products, Inc. Pipeline Products & Ongoing Clinical Trials Overview 315

5.151 University of Akron Company Overview 320

5.151.1 University of Akron Pipeline Products & Ongoing Clinical Trials Overview 320

5.152 University of Galway Company Overview 321

5.152.1 University of Galway Pipeline Products & Ongoing Clinical Trials Overview 321

5.153 University of Grenoble Alpes Company Overview 322

5.153.1 University of Grenoble Alpes Pipeline Products & Ongoing Clinical Trials Overview 322

5.154 University of Kansas Company Overview 323

5.154.1 University of Kansas Pipeline Products & Ongoing Clinical Trials Overview 323

5.155 University of Minnesota Company Overview 324

5.155.1 University of Minnesota Pipeline Products & Ongoing Clinical Trials Overview 324

5.156 University of North Carolina at Chapel Hill Company Overview 325

5.156.1 University of North Carolina at Chapel Hill Pipeline Products & Ongoing Clinical Trials Overview 325

5.157 University of Pennsylvania Company Overview 326

5.157.1 University of Pennsylvania Pipeline Products & Ongoing Clinical Trials Overview 326

5.158 University of Toledo Company Overview 327

5.158.1 University of Toledo Pipeline Products & Ongoing Clinical Trials Overview 327

5.159 Virginia Commonwealth University Company Overview 328

5.159.1 Virginia Commonwealth University Pipeline Products & Ongoing Clinical Trials Overview 328

5.160 WoundZipper Inc Company Overview 329

5.160.1 WoundZipper Inc Pipeline Products & Ongoing Clinical Trials Overview 329

5.161 Xcede Technologies Inc Company Overview 330

5.161.1 Xcede Technologies Inc Pipeline Products & Ongoing Clinical Trials Overview 330

5.162 Xian Huanuo Biotech Co Ltd Company Overview 333

5.162.1 Xian Huanuo Biotech Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 333

5.163 Yale University Company Overview 334

5.163.1 Yale University Pipeline Products & Ongoing Clinical Trials Overview 334

5.164 Yantai Zhenghai Biological Technology Co Ltd Company Overview 335

5.164.1 Yantai Zhenghai Biological Technology Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 335

5.165 Z-Medica LLC Company Overview 336

5.165.1 Z-Medica LLC Pipeline Products & Ongoing Clinical Trials Overview 336

5.166 ZSX Medical LLC Company Overview 339

5.166.1 ZSX Medical LLC Pipeline Products & Ongoing Clinical Trials Overview 339

6 Wound Closure Devices- Recent Developments 342

6.1 Jun 28, 2023: Medline Announces Leadership Transition Naming New CEO and President & COO 342

6.2 Jun 26, 2023: Covalon Announces Participation in APIC Annual Conference & Exposition on June 26 – 28, 2023 in Orlando, Florida 342

6.3 May 25, 2023: Sigachi Industries announces audited financial results for the quarter and financial year ended 31st March, 2023 343

6.4 May 15, 2023: Sealonix receives funding for sealant products development 343

6.5 May 12, 2023: Olympus announces consolidated financial results for the fiscal year ended March 31, 2023 344

6.6 May 11, 2023: Medtronic to announce financial results for its fourth quarter and full fiscal year 2023 344

6.7 May 10, 2023: ThermoGenesis Holdings to Announce Financial Results for the First Quarter Ended March 31, 2023 and Provide a Corporate Strategic Update 344

6.8 May 09, 2023: Grifols delivers strong first quarter financials with 23% revenue growth and an adjusted EBITDA margin above guidance of 21% 345

6.9 May 04, 2023: Cardinal Health reports third quarter fiscal year 2023 results and raises fiscal year 2023 non-gaap eps guidance 346

6.10 May 03, 2023: Sanara MedTech announces Q1 earnings release and conference call dates 348

6.11 May 02, 2023: MIMEDX announces first quarter 2023 operating and financial results 348

6.12 Apr 26, 2023: Merit Medical reports results for first quarter March 31, 2023 350

6.13 Apr 26, 2023: Smith & Nephew announces Q1 2023 trading update 351

6.14 Apr 19, 2023: Anika to issue first quarter 2023 financial results on Tuesday, may 9, 2023 354

6.15 Apr 18, 2023: Johnson & Johnson Reports Q1 2023 Results 354

6.16 Apr 12, 2023: Medtronic has a layoff in California 356

6.17 Apr 11, 2023: J&J talc unit 2nd bankruptcy must be dismissed 356

6.18 Apr 10, 2023: Henry Ford Health Appoints New Orthopedics Chair and Medical Director 356

6.19 Apr 06, 2023: Merit Medical Systems to Announce First Quarter 2023 Results on April 26, 2023 357

6.20 Apr 06, 2023: Smith & Nephew Notice of First Quarter 2023 Trading Report 357

6.21 Apr 03, 2023: Cook Medical receives Vizient contract for endoscopy devices 358

6.22 Mar 30, 2023: ThermoGenesis Holdings Announces Year End 2022 Financial Results and Provides Corporate Update 359

6.23 Mar 29, 2023: Baxter to Host Annual Meeting of Stockholders in Virtual Format 360

6.24 Mar 28, 2023: ThermoGenesis Holdings to Announce Financial Results for the Year Ended December 31, 2022 and Provide a Corporate Strategic Update 360

6.25 Mar 28, 2023: Stryker announces Annual Meeting of Shareholders 360

6.26 Mar 16, 2023: Thermogenesis Announces $3 Million Private Placement Priced at-the-market Under Nasdaq Rules 361

6.27 Mar 16, 2023: Medtronic joins in $25M funding round for home monitoring company 361

6.28 Mar 09, 2023: Covalon Announces Voting Results from Fiscal 2022 Annual and Special Meeting of Shareholders 361

6.29 Mar 08, 2023: Asahi Kasei Corp. Announces Change in Representative Directors 361

6.30 Mar 06, 2023: Anika Reports Fourth Quarter and Year-End Fiscal 2022 Financial Results 361

6.31 Mar 06, 2023: Smith & Nephew Announces Annual Financial Report 2022 363

6.32 Mar 06, 2023: Smith & Nephew Notice of 2023 Annual General Meeting 363

6.33 Mar 03, 2023: Grifols Announces Full Year 2022 Earnings 363

6.34 Feb 22, 2023: Thomas Glanzmann new Grifols Executive Chairman, after Steven F. Mayer resignation 364

6.35 Feb 22, 2023: Sanara MedTech Announces Unaudited Preliminary Results for the Fourth Quarter and Full Year 2022 365

6.36 Feb 21, 2023: Anika to Issue Fourth Quarter and Year-End 2022 Financial Results on Monday, March 6, 2023 366

6.37 Feb 21, 2023: Smith & Nephew Announces Fourth Quarter and Full Year 2022 Results 366

6.38 Feb 15, 2023: Owens & Minor Announces Fourth Quarter & Full Year 2022 Earnings Release Date and Conference Call 367

6.39 Feb 10, 2023: Olympus Announces Consolidated Financial Results for the Third Quarter and Full-year Forecasts for Fiscal 2023 367

6.40 Feb 10, 2023: Elanix Biotechnologies resignation and nomination in the supervisory board 368

6.41 Feb 09, 2023: Baxter Reports Fourth-Quarter and Full-Year 2022 Results 368

6.42 Feb 08, 2023: Asahi Kasei Announces Consolidated Results for 1st to 3rd Quarter Fiscal 2022 371

6.43 Feb 03, 2023: Merit Medical Systems to Announce Fourth Quarter and Year End 2022 Results and Issue Fiscal Year 2023 Guidance on February 22, 2023 371

6.44 Feb 02, 2023: Cardinal Health Reports Second Quarter Fiscal Year 2023 Results and Raises Fiscal Year 2023 Non-GAAP EPS Guidance 371

6.45 Feb 02, 2023: Zeria Pharmaceutical Announces Consolidated Financial Results for the First Nine Months of the Fiscal Year Ending March 31, 2023 373

6.46 Jan 10, 2023: Aspen Surgical Announces CEO Succession 374

6.47 Jan 09, 2023: MIMEDX Confirms Fourth Quarter and Full Year 2022 Net Sales Expectations, Comments on Evolving Medicare Reimbursement Landscape and Provides Corporate Updates 374

6.48 Jan 03, 2023: MIMEDX Appoints Ricci S. Whitlow as Chief Operating Officer 376

6.49 Dec 19, 2022: Cardinal Health Names Aaron Alt Chief Financial Officer 376

6.50 Dec 19, 2022: Cadila Pharmaceuticals appoints Ashraf Allam as Global COO 377

6.51 Dec 13, 2022: Johnson & Johnson to Host Investor Conference Call on Fourth-Quarter Results 377

6.52 Dec 08, 2022: MIMEDX Announces Wound & Surgical Product Pipeline Expansion via In-Licensing and Distribution Agreement with Turn Therapeutics 377

6.53 Dec 07, 2022: Cook Medical welcomes Dr. John A. Kaufman as Chief Medical Officer 378

6.54 Dec 07, 2022: Johnson & Johnson to Participate in the 41st Annual J.P. Morgan Healthcare Conference 379

6.55 Nov 23, 2022: Medtronic Reports Quarterly Earnings 379

6.56 Nov 22, 2022: Medtronic reports second quarter fiscal 2023 financial results 379

6.57 Nov 15, 2022: Medtronic Set to Announce Earnings on Tuesday 385

6.58 Nov 11, 2022: Olympus Consolidated Financial Results for the Six Months of the Fiscal Year Ending March 31, 2023 385

6.59 Nov 11, 2022: Olympus Announces Consolidated Financial Results for the Six Months of the Fiscal Year Ending March 31, 2023 387

6.60 Nov 09, 2022: Asahi Kasei announces Consolidated Results for 1st and 2nd Quarter Fiscal 2022 387

6.61 Nov 08, 2022: Anika Reports Third Quarter Fiscal 2022 Financial Results 387

6.62 Nov 02, 2022: Zeria Pharmaceutical announces Summary of Financial Results for the second quarter 2023 390

6.63 Oct 25, 2022: Anika to Issue Third Quarter 2022 Financial Results on Tuesday, November 8, 2022 391

6.64 Oct 21, 2022: Olympus Announces Leadership Succession Plan 391

6.65 Oct 21, 2022: Olympus Corp Notice Concerning Changes of Representative Executive Officer and Management Team 391

6.66 Oct 18, 2022: Johnson & Johnson Reports Q3 2022 Results 391

6.67 Oct 13, 2022: Merit Medical Systems to Announce Third Quarter Results on October 26, 2022 394

6.68 Oct 11, 2022: Kuros Biosciences to present positive clinical data for MagnetOs at NASS 2022 Annual Meeting 394

6.69 Oct 06, 2022: Integra LifeSciences appoints Harvinder Singh as Executive Vice President, President Of Co.”s International Business 395

6.70 Oct 06, 2022: Integra LifeSciences Announces Key Executive Appointment 395

6.71 Sep 29, 2022: Artivion AORT Appoints Elizabeth Hoff to its Board 396

6.72 Sep 28, 2022: Covalon to Participate in the 12th International Pediatric Intestinal Failure and Rehabilitation Symposium in Toronto 396

6.73 Sep 26, 2022: Covalon to Showcase Infection Prevention Solutions at the Association for Vascular Access Annual Scientific Meeting 397

6.74 Sep 13, 2022: Johnson & Johnson to Host Investor Conference Call on Third-Quarter Results 399

6.75 Sep 08, 2022: Cardinal Health Announces Pharmaceutical Segment Organizational Changes 399

6.76 Sep 08, 2022: Robert G. Riney Named Henry Ford Health President and CEO 400

6.77 Sep 08, 2022: Covalon announces expansion of its United States Pediatric Hospital Customer Base 400

6.78 Sep 07, 2022: Baxter to Host Third-Quarter 2022 Financial Results Conference Call for Investors 401

6.79 Sep 07, 2022: Medtronic to appear at September investor conferences 401

6.80 Sep 06, 2022: MiMedx Announces Leadership Transition 402

6.81 Sep 06, 2022: Sanara MedTech to Present at the Virtual MicroCap Leadership Summit 403

6.82 Sep 05, 2022: Sanofi announce Evolution of the Board of Directors 403

6.83 Aug 29, 2022: Covalon Announces Third Quarter Fiscal 2022 Results 404

6.84 Aug 24, 2022: Johnson & Johnson Appoints Larry Merlo as Non-Executive Chair Designate of Planned New Consumer Health Company 404

6.85 Aug 24, 2022: Artivion to Present at the Gilmartin Group Emerging Growth Company Showcase 405

6.86 Aug 24, 2022: JNJ Appoints Merlo as Non-Executive Chair Designate 405

6.87 Aug 23, 2022: Medtronic reports first quarter fiscal 2023 financial results 405

6.88 Aug 23, 2022: Medtronic Announces Quarterly Earnings Results 408

6.89 Aug 20, 2022: Herbert Smith Freehills advises Sanofi on €300 million equity investment in Innovent 411

6.90 Aug 16, 2022: Sanara MedTech Announces Second Quarter 2022 Results 411

6.91 Aug 11, 2022: Cardinal Health Reports Fourth Quarter and Full Year Results for Fiscal Year 2022 412

6.92 Aug 11, 2022: ThermoGenesis Holdings Announces Financial Results for the Second Quarter Ended June 30, 2022 and Provides Corporate Update 414

7 Appendix 437

Table

Wound Closure Devices – Pipeline Products by Stage of Development 31

Wound Closure Devices – Pipeline Products by Segment 32

Wound Closure Devices – Pipeline Products by Territory 34

Wound Closure Devices – Pipeline Products by Regulatory Path 36

Wound Closure Devices – Pipeline Products by Estimated Approval Date 37

Wound Closure Devices – Ongoing Clinical Trials 38

Wound Closure Devices Companies – Pipeline Products by Stage of Development 39

Wound Closure Devices – Pipeline Products by Stage of Development 45

3-D Matrix Europe SAS Pipeline Products & Ongoing Clinical Trials Overview 52

NU-MAX – Product Status 52

NU-MAX – Product Description 52

3-D Matrix Europe SAS – Ongoing Clinical Trials Overview 53

NU-MAX – First-in-Human Trial of the Safety and Performance of NU-MAX (IEIK13) as a Hemostatic Agent in Intracranial Neurosurgery 54

3-D Matrix Inc Pipeline Products & Ongoing Clinical Trials Overview 55

PuraStat – Inflammatory Bowel Disease – Product Status 55

PuraStat – Inflammatory Bowel Disease – Product Description 55

3-D Matrix Ltd Pipeline Products & Ongoing Clinical Trials Overview 56

PuraStat – Product Status 56

PuraStat – Product Description 56

TDM-623 – Product Status 57

TDM-623 – Product Description 57

3-D Matrix Ltd – Ongoing Clinical Trials Overview 58

PuraStat – A Multi-center, Single Arm Post-market Clinical Study to Confirm Safety and Performance of Purastat Absorbable Haemostatic Material for the Management of Bleeding after Open Liver Resection 59

PuraStat – A Study to Evaluate the Effectiveness of Purastat in the Prevention of Delayed Bleeding after EMR of Non-ampullary Duodenal Lesions 59

PuraStat – Colorectal Endoscopic Mucosal Resection and Delayed Bleeding: A Prospective Multicentre Randomized Controlled Superiority Trial Comparing PuraStat with Conventional Practice to Reduce the Risk of Delayed Bleeding after Colorectal Endoscopic Mucosal Resection in High-risk Patients 59

PuraStat – Efficacy of PuraStat for the Prevention of Delayed Bleeding after Endoscopic Resection of Colorectal Lesions 60

PuraStat – Endoscopically-delivered Purastat for the Treatment of Haemorrhagic Radiation Proctopathy: A Randomised Feasibility Study 60

PuraStat – Haemostatic Gel Prophylaxis for Post Duodenal Endoscopic Resection Bleeding 60

PuraStat – Prospective, Multicenter Randomized Controlled Trial of the Self-assembling Hemostatic Gel Purastat to Prevent Delayed Bleeding after Endoscopic Resections 61

PuraStat – The Hemostatic Potential of TDM-621 on Ascending Aortic Surgery 61

PuraStat – Treatment of Immediate and Prevention of Delayed Bleeding After Endoscopic Retrograde Cholangiopancreatography Sphincterothomy or Precut with a Novel Self-assembling Peptide Hemostatic Gel. A Single Centre Prospective Observational Nonrandomized Study 61

Abyrx, Inc. Pipeline Products & Ongoing Clinical Trials Overview 62

Soft Tissue Hemostat – Product Status 62

Soft Tissue Hemostat – Product Description 62

ACell Inc Pipeline Products & Ongoing Clinical Trials Overview 63

MicroMatrix – Product Status 63

MicroMatrix – Product Description 63

Acro Biomedical Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 64

ACROHCM – Product Status 64

ACROHCM – Product Description 64

Actamax Surgical Materials LLC Pipeline Products & Ongoing Clinical Trials Overview 65

Actamax Adhesion Barrier – Product Status 65

Actamax Adhesion Barrier – Product Description 65

Actamax Surgical Materials LLC – Ongoing Clinical Trials Overview 66

Actamax Adhesion Barrier – A Randomized, Controlled, Multi-center Study to Assess the Safety and Efficacy of Actamax Adhesion Barrier in Women undergoing Laparoscopic Abdominopelvic Surgery with a Myomectomy Followed by Second Look Laparoscopy (SLL) 67

Adhesys Medical GmbH Pipeline Products & Ongoing Clinical Trials Overview 68

Vivo – Product Status 68

Vivo – Product Description 68

Advanced Biotech Products Pvt Ltd Pipeline Products & Ongoing Clinical Trials Overview 69

Hemocoll – Product Status 69

Hemocoll – Product Description 69

Advanced Medical Solutions Group plc Pipeline Products & Ongoing Clinical Trials Overview 70

Large Wounds Closure Device – Product Status 70

Large Wounds Closure Device – Product Description 70

LiquiBand – Product Status 71

LiquiBand – Product Description 71

Next Generation Internal Fixation And Sealant Device – Product Status 72

Next Generation Internal Fixation And Sealant Device – Product Description 72

Advanced Medical Solutions Group plc – Ongoing Clinical Trials Overview 73

LiquiBand – A Prospective Randomized Controlled Trial Comparing Cyanoacrylate Skin Adhesive with Staple for Surgical Incision Closure after Laparoscopic / Robotic Bowel Resection 74

AFYX Therapeutics A/S Pipeline Products & Ongoing Clinical Trials Overview 75

Rivelin Plain Patch – Product Status 75

Rivelin Plain Patch – Product Description 75

Alafair Biosciences Inc Pipeline Products & Ongoing Clinical Trials Overview 76

VersaWrap Adhesion Barrier – Product Status 76

VersaWrap Adhesion Barrier – Product Description 76

Albert Ludwigs University of Freiburg Pipeline Products & Ongoing Clinical Trials Overview 77

Biohybrid Membrane – Product Status 77

Biohybrid Membrane – Product Description 77

Aleo BME Inc Pipeline Products & Ongoing Clinical Trials Overview 78

BP Glue – Product Status 78

BP Glue – Product Description 78

Dural Sealant – Product Status 79

Dural Sealant – Product Description 79

Surgical Sealant – Product Status 79

Surgical Sealant – Product Description 79

Topical Adhesive – Product Status 80

Topical Adhesive – Product Description 80

Alumend LLC Pipeline Products & Ongoing Clinical Trials Overview 81

Tissue-Bonding Adhesive – Product Status 81

Tissue-Bonding Adhesive – Product Description 81

Angiotech Pharmaceuticals Inc Pipeline Products & Ongoing Clinical Trials Overview 82

Hemaseel HMN Fibrin Sealant – Product Status 82

Hemaseel HMN Fibrin Sealant – Product Description 82

Hemaseel Thrombin Haemostatic Agent – Product Status 83

Hemaseel Thrombin Haemostatic Agent – Product Description 83

Anika Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 84

Hemostatic Patch – Product Status 84

Hemostatic Patch – Product Description 84

HYAFF Gel – Product Status 85

HYAFF Gel – Product Description 85

APRUS Bio-Medical Innovations Pvt Ltd Pipeline Products & Ongoing Clinical Trials Overview 86

Deep Wound Hemostat – Product Status 86

Deep Wound Hemostat – Product Description 86

ARC Medical Devices Inc Pipeline Products & Ongoing Clinical Trials Overview 87

Discrete – Product Status 87

Discrete – Product Description 87

Arch Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 88

AC5 – Adhesion Prevention – Product Status 88

AC5 – Adhesion Prevention – Product Description 89

AC5 – Burns – Product Status 89

AC5 – Burns – Product Description 89

AC5 – Diabetic Ulcers – Product Status 90

AC5 – Diabetic Ulcers – Product Description 90

AC5 – Pressure Ulcers – Product Status 90

AC5 – Pressure Ulcers – Product Description 91

AC5 – V – Product Status 91

AC5 – V – Product Description 91

AC5 Surgery – Fluid Barrier – Product Status 92

AC5 Surgery – Fluid Barrier – Product Description 92

AC5 Surgery – Laparascopic Procedures – Product Status 92

AC5 Surgery – Laparascopic Procedures – Product Description 93

AC5 Surgery – Open Procedures – Product Status 93

AC5 Surgery – Open Procedures – Product Description 93

AC5 Surgery – Sealant – Product Status 94

AC5 Surgery – Sealant – Product Description 94

AC5 Surgical Hemostatic Device – Product Status 94

AC5 Surgical Hemostatic Device – Product Description 95

AC5-G – Product Status 95

AC5-G – Product Description 95

Arch Therapeutics Inc – Ongoing Clinical Trials Overview 96

AC5 – V – Study to Differentiate the Key Benefits of Advanced Wound System (A Multi-Site Clinical Study) 97

Arizona State University Pipeline Products & Ongoing Clinical Trials Overview 98

Laser-Activated Nanosealant – Product Status 98

Laser-Activated Nanosealant – Product Description 98

Artivion Inc Pipeline Products & Ongoing Clinical Trials Overview 99

Bioglue Surgical Adhesive – Product Status 99

Bioglue Surgical Adhesive – Product Description 100

Artivion Inc – Ongoing Clinical Trials Overview 101

Bioglue Surgical Adhesive – A Prospective, Multicenter Study of BioGlue in the Treatment of Chinese Patients with Acute Type A Aortic Dissections 102

Bioglue Surgical Adhesive – Multi-center, Randomized, Controlled Clinical Trial of BioGlue Surgical Adhesive as an Adjunct for Structural Repair and Hemostasis in Chinese Patients with Acute Type A Aortic Dissections 102

Aura Medsystems, Inc. Pipeline Products & Ongoing Clinical Trials Overview 103

LaSTR – Skin Closure Device – Product Status 103

LaSTR – Skin Closure Device – Product Description 103

BaroStitch Pipeline Products & Ongoing Clinical Trials Overview 104

BaroStitch – Product Status 104

BaroStitch – Product Description 104

Baxter International Inc Pipeline Products & Ongoing Clinical Trials Overview 105

ACCUREACH – Product Status 105

ACCUREACH – Product Description 105

Floseal + Recothrom 10mL – Product Status 106

Floseal + Recothrom 10mL – Product Description 106

SEPRALAP – Product Status 106

SEPRALAP – Product Description 107

Tisseel Dura – Product Status 107

Tisseel Dura – Product Description 107

Bayer AG Pipeline Products & Ongoing Clinical Trials Overview 108

Polyurethane Adhesive System – Product Status 108

Polyurethane Adhesive System – Product Description 108

Bergen Medical Products Inc Pipeline Products & Ongoing Clinical Trials Overview 109

ACTACLOSE – Product Status 109

ACTACLOSE – Product Description 109

Beth Israel Deaconess Medical Center Pipeline Products & Ongoing Clinical Trials Overview 110

Portable Wound Hemostasis System – Product Status 110

Portable Wound Hemostasis System – Product Description 110

BioActive Polymers in Lund AB Pipeline Products & Ongoing Clinical Trials Overview 111

BioBarrier – Product Status 111

BioBarrier – Product Description 111

BioDevek Inc Pipeline Products & Ongoing Clinical Trials Overview 112

Adhesive Sealant – Product Status 112

Adhesive Sealant – Product Description 112

Biomedica Management Corp Pipeline Products & Ongoing Clinical Trials Overview 113

ClotBlock – Product Status 113

ClotBlock – Product Description 113

ClotFoam – Product Status 114

ClotFoam – Product Description 114

ClotGel – Product Status 114

ClotGel – Product Description 115

ClotSpray – Product Status 115

ClotSpray – Product Description 115

Biom’Up SAS Pipeline Products & Ongoing Clinical Trials Overview 116

HEMOSNOW – Product Status 116

HEMOSNOW – Product Description 116

BNC Korea Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 117

BNC-RB01 – Product Status 117

BNC-RB01 – Product Description 117

BNC-RH01 – Product Status 118

BNC-RH01 – Product Description 118

Borayer Biotechnology Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 119

Biofluid Hemostatic Membrane – Product Status 119

Biofluid Hemostatic Membrane – Product Description 119

Boston University Pipeline Products & Ongoing Clinical Trials Overview 120

Hydrogel-Based Aerosolized Sealant Dressing – Product Status 120

Hydrogel-Based Aerosolized Sealant Dressing – Product Description 120

Calmare Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 121

Wound Sealant – Product Status 121

Wound Sealant – Product Description 122

CardioCommand Inc Pipeline Products & Ongoing Clinical Trials Overview 123

Tournicath Device – Product Status 123

Tournicath Device – Product Description 123

Cellphire Inc Pipeline Products & Ongoing Clinical Trials Overview 124

Thromboderm – Product Status 124

Thromboderm – Product Description 124

Thrombosomes – Product Status 125

Thrombosomes – Product Description 125

Ceramicos Para Aplicacoes Medicas SA Pipeline Products & Ongoing Clinical Trials Overview 126

HemoKi – Product Status 126

HemoKi – Product Description 126

Clemson University Pipeline Products & Ongoing Clinical Trials Overview 127

Surgical Adhesive Hydrogel – Product Status 127

Surgical Adhesive Hydrogel – Product Description 127

Cohera Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 128

Sylys Surgical Sealant – Drug Delivery – Product Status 128

Sylys Surgical Sealant – Drug Delivery – Product Description 128

Sylys Surgical Sealant – Hernia Mesh Fixation – Product Status 129

Sylys Surgical Sealant – Hernia Mesh Fixation – Product Description 129

Sylys Surgical Sealant – Orthopedic – Product Status 129

Sylys Surgical Sealant – Orthopedic – Product Description 130

Columbia University Pipeline Products & Ongoing Clinical Trials Overview 131

Hemostatic Wound Dressing – Product Status 131

Hemostatic Wound Dressing – Product Description 131

Covalent Medical, Inc. (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 132

Covabond – Product Status 132

Covabond – Product Description 132

CovaSTAT – Product Status 133

CovaSTAT – Product Description 133

Covalon Technologies Ltd Pipeline Products & Ongoing Clinical Trials Overview 134

ColActive THP – Product Status 134

ColActive THP – Product Description 134

CovaStat BioActive Absorbable Hemostatic Sponge – Product Status 135

CovaStat BioActive Absorbable Hemostatic Sponge – Product Description 135

Covidien Ltd Pipeline Products & Ongoing Clinical Trials Overview 136

Soft Tissue Repair Device – Product Status 136

Soft Tissue Repair Device – Product Description 136

CR Bard Inc Pipeline Products & Ongoing Clinical Trials Overview 137

Absorbable Hemostat – Product Status 137

Absorbable Hemostat – Product Description 137

New Hemostat 1 – Product Status 138

New Hemostat 1 – Product Description 138

New Hemostat 2 – Product Status 138

New Hemostat 2 – Product Description 138

Progel Dural Sealant – Product Status 139

Progel Dural Sealant – Product Description 139

Progel Emerald – Product Status 139

Progel Emerald – Product Description 139

ProGEL-VS – Product Status 140

ProGEL-VS – Product Description 140

Tissue Adhesive – Product Status 140

Tissue Adhesive – Product Description 141

Tridyne Peripheral – Product Status 141

Tridyne Peripheral – Product Description 141

Cresilon Inc Pipeline Products & Ongoing Clinical Trials Overview 142

TRAUMAGEL – Product Status 142

TRAUMAGEL – Product Description 142

Department of Biomedical Engineering Columbia University Pipeline Products & Ongoing Clinical Trials Overview 143

Biomimetic Lung Sealant – Product Status 143

Biomimetic Lung Sealant – Product Description 143

DSM Biomedical BV Pipeline Products & Ongoing Clinical Trials Overview 144

Dural Membrane Sealant – Product Status 144

Dural Membrane Sealant – Product Description 144

Duke University Pipeline Products & Ongoing Clinical Trials Overview 145

Intrauterine Adhesion Barrier – Product Status 145

Intrauterine Adhesion Barrier – Product Description 145

Eidgenossische Materialprufungs- und Forschungsanstalt Pipeline Products & Ongoing Clinical Trials Overview 146

Polymer Patch – Product Status 146

Polymer Patch – Product Description 146

Elastagen Pty Ltd Pipeline Products & Ongoing Clinical Trials Overview 147

MeTro – Surgical Glue – Product Status 147

MeTro – Surgical Glue – Product Description 147

Emory University Pipeline Products & Ongoing Clinical Trials Overview 148

Steroidal Hemostatic Surgical Adhesive – Product Status 148

Steroidal Hemostatic Surgical Adhesive – Product Description 148

Endomedix Inc Pipeline Products & Ongoing Clinical Trials Overview 149

Surgical Hemostat – Intracranial Surgery – Product Status 149

Surgical Hemostat – Intracranial Surgery – Product Description 149

Topical Hemostat – Product Status 150

Topical Hemostat – Product Description 150

Entegrion Inc Pipeline Products & Ongoing Clinical Trials Overview 151

Stasix – Product Status 151

Stasix – Product Description 151

Ethicon Endo-Surgery Inc Pipeline Products & Ongoing Clinical Trials Overview 152

Bioseal Next Gen Device – Product Status 152

Bioseal Next Gen Device – Product Description 152

Ethicon US LLC Pipeline Products & Ongoing Clinical Trials Overview 153

Next Gen Hemostat Kit – Product Status 153

Next Gen Hemostat Kit – Product Description 153

PRINEO Next Generation – Product Status 154

PRINEO Next Generation – Product Description 154

SURGIFLO – Sterile Field Preparation – Product Status 154

SURGIFLO – Sterile Field Preparation – Product Description 155

Ethicon US LLC – Ongoing Clinical Trials Overview 156

PRINEO Next Generation – The Effects of Post-Operative Interventions on Surgical Site Occurrences in Abdominal Wall Reconstructions: A Randomized Controlled Trial 157

ETX Pharma Inc Pipeline Products & Ongoing Clinical Trials Overview 158

ETX-302 – Product Status 158

ETX-302 – Product Description 158

Fistula Solution Corp Pipeline Products & Ongoing Clinical Trials Overview 159

Limpet – Product Status 159

Limpet – Product Description 159

FzioMed Inc Pipeline Products & Ongoing Clinical Trials Overview 160

Oxiplex/AP – Product Status 160

Oxiplex/AP – Product Description 160

Oxiplex/IU – Product Status 161

Oxiplex/IU – Product Description 161

Gamma Diagnostics Inc Pipeline Products & Ongoing Clinical Trials Overview 162

GammaSeal – Product Status 162

GammaSeal – Product Description 162

GammaTF – Product Status 163

GammaTF – Product Description 163

GATT Technologies BV Pipeline Products & Ongoing Clinical Trials Overview 164

GATT-Patch – Product Status 164

GATT-Patch – Product Description 164

GATT-Powder – Product Status 165

GATT-Powder – Product Description 165

GATT-Spray – Product Status 165

GATT-Spray – Product Description 166

GATT-Tape – Product Status 166

GATT-Tape – Product Description 166

GATT Technologies BV – Ongoing Clinical Trials Overview 167

GATT-Patch – A Prospective, Multicenter, Randomized Clinical Investigation Evaluating GATT-Patch for Hemostasis During Minimally Invasive Liver and Gallbladder Surgery 168

Genzyme Corp Pipeline Products & Ongoing Clinical Trials Overview 169

Sepraspray Adhesion Barrier – Product Status 169

Sepraspray Adhesion Barrier – Product Description 169

Haemostatix Ltd Pipeline Products & Ongoing Clinical Trials Overview 170

Haemoplax – Product Status 170

Haemoplax – Product Description 170

PeproStat – Product Status 171

PeproStat – Product Description 171

Hangzhou Kangji Medical Instrument Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 172

Automatic-Loading Ligation Clips & Applier – Product Status 172

Automatic-Loading Ligation Clips & Applier – Product Description 172

Harvard University Pipeline Products & Ongoing Clinical Trials Overview 173

Tough Adhesive – Product Status 173

Tough Adhesive – Product Description 173

Hemostasis LLC Pipeline Products & Ongoing Clinical Trials Overview 174

ACCEL Absorbable Hemostat – Product Status 174

ACCEL Absorbable Hemostat – Product Description 174

Advanced Tissue Sealant – Product Status 175

Advanced Tissue Sealant – Product Description 175

ENT Hemostat – Product Status 175

ENT Hemostat – Product Description 175

Hemostatic Gel – Product Status 176

Hemostatic Gel – Product Description 176

Sealant Applicator – Product Status 176

Sealant Applicator – Product Description 176

Hemostasis LLC – Ongoing Clinical Trials Overview 177

ACCEL Absorbable Hemostat – ACCEL Absorbable Hemostat Powder Clinical Trial 178

HLL Lifecare Ltd Pipeline Products & Ongoing Clinical Trials Overview 179

Hinstat Ext – Product Status 179

Hinstat Ext – Product Description 179

HydroGlaze BV Pipeline Products & Ongoing Clinical Trials Overview 180

HydroGlaze – Product Status 180

HydroGlaze – Product Description 180

HyperBranch Medical Technology Inc Pipeline Products & Ongoing Clinical Trials Overview 181

Adherus Vascular Sealant – Product Status 181

Adherus Vascular Sealant – Product Description 181

Tissue Plane Sealant – Product Status 182

Tissue Plane Sealant – Product Description 182

Ichor Sciences LLC Pipeline Products & Ongoing Clinical Trials Overview 183

Statbond ENT – Product Status 183

Statbond ENT – Product Description 183

Innocoll Technologies Ltd (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 184

CM004 – Product Status 184

CM004 – Product Description 184

Innotherapy Inc Pipeline Products & Ongoing Clinical Trials Overview 185

GellySil – Product Status 185

GellySil – Product Description 185

Surgical Sealant Film – Product Status 186

Surgical Sealant Film – Product Description 186

Institute of Molecular Biology of Parana Pipeline Products & Ongoing Clinical Trials Overview 187

Recombinant Fibrin Glue – Product Status 187

Recombinant Fibrin Glue – Product Description 187

InVivo Therapeutics Corp Pipeline Products & Ongoing Clinical Trials Overview 188

InVivoSeal – Product Status 188

InVivoSeal – Product Description 188

IonMed Ltd. Pipeline Products & Ongoing Clinical Trials Overview 189

BioWeld1 System – Acne – Product Status 189

BioWeld1 System – Acne – Product Description 189

BioWeld1 System – Burns And Chronic Wounds – Product Status 190

BioWeld1 System – Burns And Chronic Wounds – Product Description 190

BioWeld1 System – Skin Graft Fixation – Product Status 190

BioWeld1 System – Skin Graft Fixation – Product Description 191

Jiangxi Boenruier Biotechnology Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 192

Fluid Hemostatic Agent – Product Status 192

Fluid Hemostatic Agent – Product Description 192

Jinwoo Bio Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 193

HA Fabric Sheet Adhesive Barrier – Product Status 193

HA Fabric Sheet Adhesive Barrier – Product Description 194

HA Film Adhesive Barrier – Product Status 194

HA Film Adhesive Barrier – Product Description 194

Wool Adhesive Barrier – Product Status 195

Wool Adhesive Barrier – Product Description 195

Johns Hopkins University Pipeline Products & Ongoing Clinical Trials Overview 196

Chondroitin Sulfate-based Adhesive – Product Status 196

Chondroitin Sulfate-based Adhesive – Product Description 196

Keratin Biosciences Inc Pipeline Products & Ongoing Clinical Trials Overview 197

Keratin-Based Hemostat – Product Status 197

Keratin-Based Hemostat – Product Description 197

Kollodis BioSciences Inc Pipeline Products & Ongoing Clinical Trials Overview 198

Cartilage Adhesive – Product Status 198

Cartilage Adhesive – Product Description 198

Hemostat Sealant – Product Status 198

Hemostat Sealant – Product Description 199

Kuros Biosciences AG Pipeline Products & Ongoing Clinical Trials Overview 200

KUR – 211 – Product Status 200

KUR – 211 – Product Description 200

KUR – 212 – Product Status 201

KUR – 212 – Product Description 201

Kytogenics Pharmaceuticals Inc Pipeline Products & Ongoing Clinical Trials Overview 202

Adhes-X – Product Status 202

Adhes-X – Product Description 202

Lap IQ Inc Pipeline Products & Ongoing Clinical Trials Overview 203

FAStlink – Product Status 203

FAStlink – Product Description 203

Laser Tissue Welding, Inc. Pipeline Products & Ongoing Clinical Trials Overview 204

Laser Tissue Welding Device – Product Status 204

Laser Tissue Welding Device – Product Description 204

Latch Medical Ltd Pipeline Products & Ongoing Clinical Trials Overview 205

Relialoc Skin Closure System – Product Status 205

Relialoc Skin Closure System – Product Description 205

Leader Biomedical Europe BV Pipeline Products & Ongoing Clinical Trials Overview 206

Collagen-Based Haemostatic Device – Product Status 206

Collagen-Based Haemostatic Device – Product Description 206

Rebasol – Product Status 207

Rebasol – Product Description 207

Lenvitz Medical Solutions Pvt Ltd Pipeline Products & Ongoing Clinical Trials Overview 208

Auto Clip Applicator – Product Status 208

Auto Clip Applicator – Product Description 208

Life Care Medical Devices Ltd Pipeline Products & Ongoing Clinical Trials Overview 209

LCMD-004 – Product Status 209

LCMD-004 – Product Description 209

Luna Innovations Inc Pipeline Products & Ongoing Clinical Trials Overview 210

Sutureless Absorbable Antiadhesion Film – Product Status 210

Sutureless Absorbable Antiadhesion Film – Product Description 210

TissuCoat – Product Status 211

TissuCoat – Product Description 211

Magen OrthoMed Ltd Pipeline Products & Ongoing Clinical Trials Overview 212

NerveShield – Product Status 212

NerveShield – Product Description 212

TendonShield – Product Status 213

TendonShield – Product Description 213

Massachusetts Institute of Technology Pipeline Products & Ongoing Clinical Trials Overview 214

Double-Sided Tape – Product Status 214

Double-Sided Tape – Product Description 214

Surgical Tape – Product Status 215

Surgical Tape – Product Description 215

Maxigen Biotech Inc Pipeline Products & Ongoing Clinical Trials Overview 216

MaxiGel – Product Status 216

MaxiGel – Product Description 216

Medcura Inc Pipeline Products & Ongoing Clinical Trials Overview 217

Hemogrip Foam – Product Status 217

Hemogrip Foam – Product Description 217

LifeDust – Product Status 218

LifeDust – Product Description 218

LifeFoam – Product Status 218

LifeFoam – Product Description 219

LifeGel – Product Status 219

LifeGel – Product Description 219

Medical Plasmas SL Pipeline Products & Ongoing Clinical Trials Overview 220

PlasmAction – Product Status 220

PlasmAction – Product Description 220

Medical Plasmas SL – Ongoing Clinical Trials Overview 221

PlasmAction – Air Cold Atmospheric Pressure Plasma Treatment for Acceleration of Venous Ulcer Healing 222

Medisse BV (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 223

FlexiSurge Adhesive Barrier – Product Status 223

FlexiSurge Adhesive Barrier – Product Description 223

PTMC Adhesive – Product Status 224

PTMC Adhesive – Product Description 224

PTMC Sealant – Product Status 224

PTMC Sealant – Product Description 225

Meril Life Sciences Pvt Ltd Pipeline Products & Ongoing Clinical Trials Overview 226

PeriTi – Product Status 226

PeriTi – Product Description 226

MLM Biologics Inc Pipeline Products & Ongoing Clinical Trials Overview 227

Adhesion Barrier – Product Status 227

Adhesion Barrier – Product Description 227

Biologic Barrier Membrane – Superficial Wounds – Product Status 228

Biologic Barrier Membrane – Superficial Wounds – Product Description 228

N8 Medical LLC Pipeline Products & Ongoing Clinical Trials Overview 229

Tissue Glue & Microbial Sealent – Product Status 229

Tissue Glue & Microbial Sealent – Product Description 229

Wound Closure Adhesive – Product Status 230

Wound Closure Adhesive – Product Description 230

Nanyang Technological University Pipeline Products & Ongoing Clinical Trials Overview 231

CaproGlu – Product Status 231

CaproGlu – Product Description 231

National University of Singapore Pipeline Products & Ongoing Clinical Trials Overview 232

Colon Patch – Product Status 232

Colon Patch – Product Description 232

Northwestern University Pipeline Products & Ongoing Clinical Trials Overview 233

Medical Adhesive – Product Status 233

Medical Adhesive – Product Description 233

Nurami Medical Ltd Pipeline Products & Ongoing Clinical Trials Overview 234

ArtiFix – Product Status 234

ArtiFix – Product Description 234

OptMed, Inc. Pipeline Products & Ongoing Clinical Trials Overview 235

Biosurgical Adhesive – Chronic Wounds – Product Status 235

Biosurgical Adhesive – Chronic Wounds – Product Description 235

Biosurgical Adhesive – Internal Use – Product Status 236

Biosurgical Adhesive – Internal Use – Product Description 236

Biosurgical Adhesive – Skin Tears – Product Status 236

Biosurgical Adhesive – Skin Tears – Product Description 237

Paul Scherrer Institute Pipeline Products & Ongoing Clinical Trials Overview 238

Omnibond Topical Skin Adhesive – Product Status 238

Omnibond Topical Skin Adhesive – Product Description 238

Paul Scherrer Institute – Ongoing Clinical Trials Overview 239

Omnibond Topical Skin Adhesive – A Prospective, Randomized, Single-blinded Study to Assess the Incidence of Wound Complications Following Total Knee and Hip Arthroplasty in Patients Treated with Two Different Types of Topical Skin Adhesive 240

PetVivo Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview 241

Vasculitus Wound Closure Device – Product Status 241

Vasculitus Wound Closure Device – Product Description 241

Pharming Group NV Pipeline Products & Ongoing Clinical Trials Overview 242

Recombinant Fibrin Tissue Sealant – Product Status 242

Recombinant Fibrin Tissue Sealant – Product Description 242

Polyganics BV Pipeline Products & Ongoing Clinical Trials Overview 243

3D Printed Scaffold – Product Status 243

3D Printed Scaffold – Product Description 243

ACTISEAL – Product Status 244

ACTISEAL – Product Description 244

ACTISEAL – Adjacent Indications – Product Status 244

ACTISEAL – Adjacent Indications – Product Description 245

LIQOSEAL – Dura Sealing Patch – Product Status 245

LIQOSEAL – Dura Sealing Patch – Product Description 245

LIQOSEAL – Spine Application – Product Status 246

LIQOSEAL – Spine Application – Product Description 246

Polyganics BV – Ongoing Clinical Trials Overview 247

LIQOSEAL – Dura Sealing Patch – Randomized, Two-arm, Multicenter Study to Evaluate the Safety and Efficacy of Dura Sealant Patch in Reducing CSF Leakage Following Elective Cranial Surgery 248

PolyNovo Biomaterials Pty Ltd Pipeline Products & Ongoing Clinical Trials Overview 249

Anti-Adhesion Film – Product Status 249

Anti-Adhesion Film – Product Description 249

Progress and Health Foundation Pipeline Products & Ongoing Clinical Trials Overview 250

Wound Closure Kit – Product Status 250

Wound Closure Kit – Product Description 250

Protege Biomedical LLC Pipeline Products & Ongoing Clinical Trials Overview 251

Ionic Hemostatic Mineral Bandage – Emergency Trauma – Product Status 251

Ionic Hemostatic Mineral Bandage – Emergency Trauma – Product Description 251

Protein Polymer Technologies Inc (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 252

Surgical Tissue Sealant – Product Status 252

Surgical Tissue Sealant – Product Description 252

Purdue University Pipeline Products & Ongoing Clinical Trials Overview 253

Surgical Adhesive – Product Status 253

Surgical Adhesive – Product Description 253

Surgical Sealant – Product Status 254

Surgical Sealant – Product Description 254

Radiation Monitoring Devices Inc Pipeline Products & Ongoing Clinical Trials Overview 255

Hemostatic Patch – Traumatic Injury – Product Status 255

Hemostatic Patch – Traumatic Injury – Product Description 255

Regenics AS Pipeline Products & Ongoing Clinical Trials Overview 256

Collex – Product Status 256

Collex – Product Description 256

Vernex – Product Status 257

Vernex – Product Description 257

Resorba GmbH Pipeline Products & Ongoing Clinical Trials Overview 258

Antibiotic Hemostat – Product Status 258

Antibiotic Hemostat – Product Description 258

RESORBA – Cardiac Surgery – Product Status 259

RESORBA – Cardiac Surgery – Product Description 259

Rice University Pipeline Products & Ongoing Clinical Trials Overview 260

KOD Hydrogel Hemostat – Product Status 260

KOD Hydrogel Hemostat – Product Description 260

Rutgers The State University of New Jersey Pipeline Products & Ongoing Clinical Trials Overview 261

Biodegradable Film Implant – Product Status 261

Biodegradable Film Implant – Product Description 261

Samyang Biopharmaceuticals Corp Pipeline Products & Ongoing Clinical Trials Overview 262

Surgical Sealant – Product Status 262

Surgical Sealant – Product Description 262

Sanofi Biosurgery Inc Pipeline Products & Ongoing Clinical Trials Overview 263

LeSeal – Product Status 263

LeSeal – Product Description 263

Lumagel – Product Status 264

Lumagel – Product Description 264

Sea Run Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview 265

SEA-STAT – Product Status 265

SEA-STAT – Product Description 265

SEA-STAT CNS – Product Status 266

SEA-STAT CNS – Product Description 266

Sealantis Ltd. Pipeline Products & Ongoing Clinical Trials Overview 267

Seal-G – Product Status 267

Seal-G – Product Description 267

Seal-G MIST – Product Status 268

Seal-G MIST – Product Description 268

Sealantis Tissue Adhesive – Product Status 268

Sealantis Tissue Adhesive – Product Description 269

Sealantis Ltd. – Ongoing Clinical Trials Overview 270

Seal-G – Seal-G and Seal-G MIST Study for Reinforcement and Protection of Colonic Anastomoses in Subjects Undergoing Colonic Resection 271

Seal-G MIST – Seal-G and Seal-G MIST Study for Reinforcement and Protection of Colonic Anastomoses in Subjects Undergoing Colonic Resection 272

Seikagaku Corp Pipeline Products & Ongoing Clinical Trials Overview 273

SI-449 Adhesion Barrier System – Product Status 273

SI-449 Adhesion Barrier System – Product Description 273

Seikagaku Corp – Ongoing Clinical Trials Overview 274

SI-449 Adhesion Barrier System – A Randomized, Controlled, Pivotal Study of SI-449 Adhesion Barrier in Patients with Temporary Ileostomy 275

Selio Medical Pipeline Products & Ongoing Clinical Trials Overview 276

Selio Sealant System – Product Status 276

Glossary

Figures

Wound Closure Devices – Pipeline Products by Stage of Development 30

Wound Closure Devices – Pipeline Products by Segment 31

Wound Closure Devices – Pipeline Products by Territory 33

Wound Closure Devices – Pipeline Products by Regulatory Path 35

Wound Closure Devices – Pipeline Products by Estimated Approval Date 37

Wound Closure Devices – Ongoing Clinical Trials 38

Frequently asked questions

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