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Arrowhead Pharmaceuticals Inc (Arrowhead) is a biotech company that develops and commercializes gene silencing therapeutics. The company’s pipeline products include Plozasiran (ARO-APOC3) which targets hypertriglyceridemia, familial chylomicronemia syndrome and dyslipidemia; Zodasiran (ARO-ANG3) treats dyslipidemia and homozygous familial hypercholesterolemia; Olpasiran for cardiovascular disease; ARO-ALK7 and ARO-INHBE targets obesity; GSK4532990 and ARO-PNPLA3 targets metabolic dysfunction–associated steatohepatitis; ARO-ATXN2 for spinocerebellar ataxia 2; ARO-RAGE targets inflammatory pulmonary diseases; aro-MMP7 for idiopathic pulmonary fibrosis; among others. It utilizes RNA chemistries and TRiM platform to target and silence disease-causing genes. Arrowhead is headquartered in Pasadena, California, the US.
Arrowhead Pharmaceuticals Inc premium industry data and analytics
Products and Services
| Products | Brands |
|---|---|
| Pipeline | TRiM - Targeted RNAi Molecule |
| Plozasiran (ARO-APOC3): | |
| Hypertriglyceridemia | |
| XYZ | |
| XYZ | |
| XYZ |
History
History section provides information on new products, mergers, acquisitions, expansions, approvals, and many more key events.
| Year | Event | Description |
|---|---|---|
| 2026 | Regulatory Approval | In May, the company secured approval from the Australian Therapeutic Goods Administration for REDEMPLO (plozasiran), a small interfering RNA (siRNA) medicine. |
| 2026 | Contracts/Agreements | In May, the company signed a license agreement with Madrigal Pharmaceuticals for Arrowhead’s investigational RNA interference therapeutic ARO-PNPLA3 to treat metabolic dysfunction-associated steatohepatitis. |
| 2026 | Contracts/Agreements | In January, the company obtained Health Canada approval for REDEMPLO (plozasiran) to lower triglycerides in adults with familial chylomicronemia syndrome. |
Competitor Comparison
| Key Parameters | Arrowhead Pharmaceuticals Inc | Blueprint Medicines Corp | BridgeBio Pharma Inc | Viridian Therapeutics Inc | aTyr Pharma Inc |
|---|---|---|---|---|---|
| Headquarters | United States of America | United States of America | United States of America | United States of America | United States of America |
| City | Pasadena | Cambridge | Palo Alto | Waltham | San Diego |
| State/Province | California | Massachusetts | California | Massachusetts | California |
| No. of Employees | 711 | 682 | 834 | 252 | 56 |
| Entity Type | Public | Private | Public | Public | Public |
Key Financial Charts
Sales Growth
Net Income Growth
Executives
| Name | Position | Board | Since | Age |
|---|---|---|---|---|
| Christopher Anzalone, PhD | President; Chief Executive Officer; Chairman | Executive Board | 2007 | 55 |
| Daniel Apel | Chief Financial Officer | Senior Management | 2025 | - |
| Patrick O’Brien | General Counsel; Chief Operating Officer | Senior Management | 2022 | 61 |
| James Hamilton, MD | Chief Medical Officer; Chief - Discovery and Translational Medicine | Senior Management | 2025 | 47 |
| Andy Davis | Senior Vice President - Cardiovascular; Head - Metabolic Franchise | Senior Management | 2023 | - |
| Non Dignissim Eros | Proin vel | Convallis | 2026 | XY |
| Non Dignissim Eros | Proin vel | Convallis | 2026 | XY |
| Non Dignissim Eros | Proin vel | Convallis | 2026 | XY |
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