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Denali Therapeutics Inc (Denali Therapeutics) is a clinical-stage biopharmaceutical company that develops a portfolio of product candidates engineered to cross the blood-brain barrier for neurodegenerative diseases and lysosomal storage diseases. The company's proprietary platform technology called the Transport Vehicle enabled programs include tividenofusp alfa (DNL310, ETV:IDS) for mucopolysaccharidosis II (MPS II or Hunter syndrome); BIIB122/DNL151 (LRRK2 inhibitor) for Parkinson’s disease; and DNL343 (eIF2B activator) for amyotrophic lateral sclerosis (“ALS”). Its pipeline products include Iduronate 2-sulfatase, LRRK2, Progranulin, Sulfamidase, Alpha-L-iduronidase, eIF2B and RIPK1 (Peripheral). The company's pipeline products are intended for the treatment of Alzheimer’s disease, Parkinson’s disease, lysosomal storage disorder disease, neurodegeneration, amyotrophic lateral sclerosis and other indications. Denali Therapeutics is headquartered in San Francisco, California, the US.
Headquarters
United States of America
Address
161 Oyster Point Blvd, South San Francisco, California, 94080-1910
Website
www.denalitherapeutics.com
Telephone
1 650 8668548
No of Employees
375
Industry
Pharmaceuticals and Healthcare
Ticker Symbol & Exchange
DNLI (NASD)
Revenue (2022)
$330.5M
204.7%
(2022 vs 2021)
EPS
XYZ
Net Income (2022)
XYZ
55.5%
(2022 vs 2021)
Market Cap*
$2.6B
Net Profit Margin (2022)
XYZ
85.4%
(2022 vs 2021)
* As of and is in US$
Denali Therapeutics Inc premium industry data and analytics
Products and Services
| Products |
|---|
| Pipeline |
| Lysosomal Function |
| LRRK2: Parkinson's Disease |
| XYZ |
| XYZ |
| XYZ |
Competitor Comparison
| Key Parameters | Denali Therapeutics Inc | Eli Lilly and Co | Biogen Inc | Ionis Pharmaceuticals Inc | Prothena Corp Plc |
|---|---|---|---|---|---|
| Headquarters | United States of America | United States of America | United States of America | United States of America | Ireland |
| City | South San Francisco | Indianapolis | Cambridge | Carlsbad | Dublin |
| State/Province | California | Indiana | Massachusetts | California | - |
| No. of Employees | 375 | 43,000 | 7,570 | 927 | 173 |
| Entity Type | Public | Public | Public | Public | Public |
Key Financial Charts
Sales Growth
Net Income Growth
Executives
| Name | Position | Board | Since | Age |
|---|---|---|---|---|
| Vicki Sato | Chairman | Executive Board | 2016 | 74 |
| Ryan J. Watts | Chief Executive Officer; President; Director | Executive Board | 2015 | 47 |
| Cindy Dunkle | Chief People Officer | Senior Management | - | - |
| Carole Ho | Chief Medical Officer; Head - Development | Senior Management | 2015 | 50 |
| Joe Lewcock | Chief Scientific Officer; Head - Discovery | Senior Management | - | - |
| Non Dignissim Eros | Proin vel | Convallis | 2024 | XY |
| Non Dignissim Eros | Proin vel | Convallis | 2024 | XY |
| Non Dignissim Eros | Proin vel | Convallis | 2024 | XY |
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