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4D Molecular Therapeutics Inc: Overview

4D Molecular Therapeutics Inc (4DMT) is a gene therapy company that discovers and develops targeted and proprietary AAV gene therapy vectors and therapeutic products. The company’s pipeline products include 4D-125, 4D-110, 4D-150, 4D-175, 4D-310, 4D-725, and 4D-710. It has developed a technology platform, Therapeutic Vector Evolution, that facilitates the creation of customized gene delivery vehicles (novel AAV vectors) to deliver genes to any tissue or organ in the body. 4DMT develops pipeline products that target areas such as liver, retina, heart, brain, skeletal muscle, and lungs. The company works in partnership with F. Hoffmann-La Roche Ltd to design, develop and commercialize AAV products for use in ophthalmology indications. 4DMT is headquartered in Emeryville, California, the US.

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Headquarters United States of America

Address 5858 Horton Street #455, Emeryville, California, 94608


Telephone 1 510 5052680

No of Employees 147

Industry Pharmaceuticals and Healthcare

Ticker Symbol & Exchange FDMT (NASD)

Revenue (2022) $20.7M 562.3% (2022 vs 2021)

EPS XYZ

Net Income (2022) XYZ 6.2% (2022 vs 2021)

Market Cap* $1.2B

Net Profit Margin (2022) XYZ 85.8% (2022 vs 2021)

* As of and is in US$
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Products and Services

Products
Pipeline
Retina:
Choroideremia (4D-110)
XYZ
XYZ
XYZ
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History

History section provides information on new products, mergers, acquisitions, expansions, approvals, and many more key events.

Year Event Description
2024 Contracts/Agreements In January, the company entered into a partnership with Arbor Biotechnologies to create six AAV-delivered CRISPR/Cas-based therapeutic candidates.
2024 Regulatory Approval In January, the company received Rare Pediatric Disease Designation (RPDD) from U.S. Food and Drug Administration (FDA) for its product candidate aerosolized 4D-710 for the treatment of cystic fibrosis (CF) lung disease.
2023 Regulatory Approval In December, the company received Regenerative Medicine Advanced Therapy (RMAT) designation from the U.S. Food and Drug Administration (FDA) for the investigational genetic medicine candidate 4D-150 for intravitreal treatment of wet age-related macular degeneration (wet AMD).
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Competitor Comparison

Key Parameters 4D Molecular Therapeutics Inc AbbVie Inc Takeda Pharmaceutical Co Ltd Regeneron Pharmaceuticals Inc Vertex Pharmaceuticals Inc
Headquarters United States of America United States of America Japan United States of America United States of America
City Emeryville North Chicago Chuo-Ku Tarrytown Boston
State/Province California Illinois Tokyo New York Massachusetts
No. of Employees 147 50,000 49,095 13,450 5,400
Entity Type Public Public Public Public Public
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Executives
Name Position Board Since Age
John F. Milligan, Ph.D. Chairman Executive Board 2020 62
David Kirn, M.D. Chief Executive Officer; Director Executive Board 2013 61
Fariborz Kamal, Ph.D. President; Chief Operating Officer Senior Management 2022 60
Robert Y. Kim, M.D Chief Medical Officer Senior Management 2023 62
Noriyuki Kasahara, M.D. Chief Scientific Officer Senior Management 2024 61
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