Mesoblast Ltd - Company Profile

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Mesoblast Ltd (Mesoblast) is a regenerative medicine company that develops regenerative cell-based products. Its lead candidate, remestemcel-L, is in Phase III clinical trials under the brand name Ryoncil for the treatment of pediatric steroid-refractory acute graft versus host disease (SR-aGVHD). Mesoblast is advancing rexlemestrocel for localized inflammatory diseases, including advanced heart failure, end-stage ischemic heart failure, and MPc-06-ID (rexlemestrocel) for the treatment of chronic low back pain. The company leverages its proprietary technology platform to create treatments for cardiac and hematological diseases, mesenchymal lineage adult stem cells (MLCs), spine and musculoskeletal disorders, and immune-mediated and inflammatory conditions.

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Headquarters Australia

Address L 38, 55 Collins St, Melbourne, Victoria, 3000


Telephone 61 3 96396036

No of Employees 81

Industry Pharmaceuticals and Healthcare

Ticker Symbol & Exchange MSB (ASX)

Revenue (2024) $17.2M 191.4% (2024 vs 2023)

EPS XYZ

Net Income (2024) XYZ -16.1% (2024 vs 2023)

Market Cap* $1.8B

Net Profit Margin (2024) XYZ 60.2% (2024 vs 2023)

* As of and is in US$
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Mesoblast Ltd premium industry data and analytics

60+

Clinical Trials

Determine Mesoblast Ltd go-to-market proposition and gain insight into the company’s clinical operations, recruitment, and trial strategy.

30+

Catalyst Calendar

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20+

Insights

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20+

Lead Sheet

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18+

Pipeline Drugs

Identify which of Mesoblast Ltd’s products will be commercialized, helping you to better contend with shifting product portfolios, and allowing you to stay one step ahead of the market.

7

Regulatory Milestones

Track drug and patent expiries along with geographies impacted.

1

Marketed Drugs

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Products and Services

Products Brands
Pipeline Revascor
Remestemcel-L: Ryoncil
Steroid-Refractory Acute Graft Versus Host Disease (Children)
XYZ
XYZ
XYZ
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History

History section provides information on new products, mergers, acquisitions, expansions, approvals, and many more key events.

Year Event Description
2025 New Products/Services In January, the company introduced Ryoncil (remestemcel-L) for steroid-refractory acute graft-versus-host disease in pediatric patients.
2024 Regulatory Approval In December, the company received approval from the US FDA for Ryoncil, a mesenchymal stromal cell (MSC) therapy.
2024 Regulatory Approval In February, the company received approval from the US Food and Drug Administration for its allogeneic cell therapy Revascor (rexlemestrocel-L) from the randomized controlled trial in children with hypoplastic left heart syndrome.
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Competitor Comparison

Key Parameters Mesoblast Ltd Cynata Therapeutics Ltd Allogene Therapeutics Inc Amniotics AB BioSenic SA
Headquarters Australia Australia United States of America Sweden Belgium
City Melbourne Cremorne San Francisco Lund Mont-Saint-Guibert
State/Province Victoria Victoria California - -
No. of Employees 81 - 150 9 7
Entity Type Public Public Public Private Public
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Executives
Name Position Board Since Age
Silviu Itescu Chief Executive Officer; Director; Managing Director Executive Board 2011 -
Eric Rose, MD Chief Medical Officer; Director Executive Board 2022 -
James M. O’Brien Chief Financial Officer Senior Management 2025 -
Philip J. Facchina Chairman Non Executive Board 2026 -
Geraldine Storton Head - Regulatory Affairs and Quality Management Senior Management 2015 -
Non Dignissim Eros Proin vel Convallis 2026 XY
Non Dignissim Eros Proin vel Convallis 2026 XY
Non Dignissim Eros Proin vel Convallis 2026 XY
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