Karyopharm Therapeutics Inc - Company Profile
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The following section provides information on Karyopharm Therapeutics Inc’s senior management, executives, CEO and key decision makers and their roles in the organization. For more insight into Karyopharm Therapeutics Inc's management and employees, unlock the full data with our company analytics monitoring tool.
Executives
Richard Paulson
Director; Chief Executive Officer; President Executive BoardMr. Richard Paulson has been the Chief Executive Officer, President and Director of the company since 2021. Prior to this, he served as Executive Vice President of Ipsen Pharmaceuticals Inc and Chief Executive Officer of Ipsen North America from February 2018 to May 2021. Previously, he served as the Vice President and General Manager U.S. Oncology Business Unit, Vice President of Marketing for the U.S. Oncology Business at Amgen. He also served as the General Manager at Pfizer South Africa and Pfizer Czech Republic.
Lori Macomber
Executive Vice President; Treasurer; Chief Financial Officer Senior ManagementMs Lori Macomber has been the Executive Vice President, Chief Financial Officer, and Treasurer of the company since January 2025. Prior to this, she served as the Chief Financial Officer at Legend Biotech Corporation from May 2022 to January 2025. Previously, she served as the Vice President, Finance at Biotech Corporation from March 2021 to May 2022. She aslo served as the Vice President of Supply Chain Finance and Controller at Biotech Corporation from 2019 to March 2021. She served as the Business Unit Controller, at Ametek from 2018 to 2019. She served as the U.S. Chief Financial Officer and Controller at Cello Health from 2017 to 2018.
Kristin Abate
Vice President; Chief Accounting Officer Senior ManagementMr. Kristin Abate has been the Vice President, and Chief Accounting Officer of the company since November 2024. Previously, he was the Vice President of Accounting of the company. Prior to this, he worked at PricewaterhouseCoopers.
Michael Mano
Chief Legal Officer; Secretary; Executive Vice President Senior ManagementMr Michael Mano has been the Executive Vice President, Chief Legal Officer and Secretary of the company since January 2026. Prior to this, he served as the Counsel, Business Development at Biogen from 2018 to 2020. Previously, he served as the Senior Counsel at Proskauer Rose LLP from 2013 to 2018.
James Accumanno
Chief Compliance Officer Senior ManagementMr. James Accumanno has been the Chief Compliance Officer of the company since 2022. Prior to this, he served in Executive Director of Legal and Compliance of the company. Prior to this, he served in variety of legal and compliance roles at Novo Nordisk and Bayer Healthcare Pharmaceuticals.
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