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MeiraGTx Holdings Plc: Overview

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MeiraGTx Holdings Plc (MeiraGTx) is a clinical-stage genetic medicine company that develops genetic therapies for rare diseases. The company’s pipeline products including AAV-hAQP1 for radiation-induced xerostomia, sjogren’s disease, PSMA radioligand xerostomia prophylaxis and treatment; AAV-GAD which treats parkinson's disease; AAV-UPF1 and AAV-CNTFR for amyotrophic lateral sclerosis; AAV-AIPL1 which targets congenital blindness; AAV-ABCA4 for the treatment of Stargardt’s disease; and AAV-BDNF which treats genetic obesity, among others. Its therapeutic areas include salivary gland, neurodegenerative disease, ophthalmology, riboswitch regulated therapies, and genetic obesity. The company operates in the US, the UK and Ireland. MeiraGTx is headquartered in New York, the US.

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Headquarters United States of America

Address 655 Third Avenue, Suite 1115, New York City, 10016


No of Employees 403

Industry Pharmaceuticals and Healthcare

Ticker Symbol & Exchange MGTX (NASD)

Revenue (2024) $81.4M 144.6% (2024 vs 2023)

EPS XYZ

Net Income (2024) XYZ 22.7% (2024 vs 2023)

Market Cap* $1.1B

Net Profit Margin (2024) XYZ 68.4% (2024 vs 2023)

   

* As of and is in US$
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Products and Services

Products
Pipeline
AAV-hAQP1 :
Radiation-Induced Xerostomia
XYZ
XYZ
XYZ
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History

History section provides information on new products, mergers, acquisitions, expansions, approvals, and many more key events.

Year Event Description
2026 Contracts/Agreements In April, the company signed an agreement with Johnson & Johnson to acquire botaretigene sparoparvovec (bota-vec), an investigational therapy for X-linked retinitis pigmentosa (XLRP).
2025 Contracts/Agreements In March, the company announced a broad strategic collaboration with Hologen Limited, a world-leading developer of multi-modal generative AI foundation models of real-world clinical data for clinical medicine and pharmaceutical drug development.
2020 Acquisitions/Mergers/Takeovers In April, the company acquired Emrys Bio Inc., a biopharmaceutical company.
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Competitor Comparison

Key Parameters MeiraGTx Holdings Plc Biogen Inc 4D Molecular Therapeutics Inc Voyager Therapeutics Inc Brain Neurotherapy Bio Inc
Headquarters United States of America United States of America United States of America United States of America United States of America
City New York City Cambridge Emeryville Lexington Columbus
State/Province New York Massachusetts California Massachusetts Ohio
No. of Employees 403 7,500 196 141 -
Entity Type Public Public Public Public Private
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Executives
Name Position Board Since Age
Keith R. Harris, Ph.D. Chairman Executive Board 2015 73
Alexandria Forbes, Ph.D. Director; President; Chief Executive Officer Executive Board 2015 61
Richard Giroux Chief Operating Officer; Chief Financial Officer Senior Management 2019 53
Robert K. Zeldin, M.D. Chief Medical Officer Senior Management 2020 61
Robert J. Wollin Secretary; General Counsel Senior Management 2020 50
Non Dignissim Eros Proin vel Convallis 2026 XY
Non Dignissim Eros Proin vel Convallis 2026 XY
Non Dignissim Eros Proin vel Convallis 2026 XY
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