Regulus Therapeutics Inc - Company Profile
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Regulus Therapeutics Inc (Regulus), a subsidiary of Novartis AG, is a biotechnology company focused on developing oligonucleotide therapeutics aimed at inhibiting dysregulated microRNA targets. The company offers researching and developing treatments for genetically based orphan diseases, particularly orphan kidney diseases such as Autosomal Dominant Polycystic Kidney Disease (ADPKD). Its pipeline product include RGLS8429 which treats ADPKD. The company's therapeutics are designed for patients with high unmet medical needs, particularly those affected by genetic kidney diseases. Regulus collaborates with industry leaders Alnylam and Ionis for intellectual property related to oligonucleotide-based therapeutics and others. Regulus Therapeutics is headquartered in San Diego, California, the US.
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Products and Services
| Products | Services |
|---|---|
| Product: | Clinical Trials |
| Pipeline Product: | |
| ADPKD- Autosomal Dominant Polycystic Kidney Disease |
History
History section provides information on new products, mergers, acquisitions, expansions, approvals, and many more key events.
| Year | Event | Description |
|---|---|---|
| 2025 | Ownership Changes | In June, the company was acquired by Novartis, a pharmaceutical company. |
| 2020 | Contracts/Agreements | In December, the company entered into a collaboration with Bio-Techne to support biomarker assay development and biomarker analysis to develop RGLS4326 for the kidney disease treatment. |
| 2015 | Contracts/Agreements | In November, Regulus Therapeutics Inc. through its collaboration and formulation development agreement with GlaxoSmithKline have expanded the development of RG-101. |
Competitor Comparison
| Key Parameters | Regulus Therapeutics Inc | Ionis Pharmaceuticals Inc | Arrowhead Pharmaceuticals Inc | Genzyme Corp |
|---|---|---|---|---|
| Headquarters | United States of America | United States of America | United States of America | United States of America |
| City | San Diego | Carlsbad | Pasadena | Cambridge |
| State/Province | California | California | California | Massachusetts |
| No. of Employees | 34 | 1,069 | 711 | - |
| Entity Type | Private | Public | Public | Private |
Executives
| Name | Position | Board | Since | Age |
|---|---|---|---|---|
| Stelios Papadopoulos, Ph.D. | Chairman | Executive Board | - | 75 |
| Jay Hagan | Chief Executive Officer; Director | Executive Board | - | 55 |
| Preston S. Klassen, MD | Research and Development; President; Director | Executive Board | - | 55 |
| Cris Calsada | Chief Financial Officer | Senior Management | - | - |
| Moh Ahmadian, Ph.D. | Vice President - Chemistry and Pharmaceutical Development | Senior Management | - | - |
| Non Dignissim Eros | Proin vel | Convallis | 2026 | XY |
| Non Dignissim Eros | Proin vel | Convallis | 2026 | XY |
| Non Dignissim Eros | Proin vel | Convallis | 2026 | XY |
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