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Rhythm Pharmaceuticals Inc: Overview

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Rhythm Pharmaceuticals Inc (Rhythm Pharmaceuticals) is a biopharmaceutical company that focuses on developing precision medicines for rare neuroendocrine diseases. The company's lead product is IMCIVREE (setmelanotide), a medicine designed to treat hyperphagia and severe obesity caused by MC4R pathway diseases. Rhythm Pharmaceuticals clinical trials program includes Bivamelagon (LB54640), for acquired hypothalamic obesity; and RM-718, a new weekly MC4R–specific agonist designed to not cause hyperpigmentation. It also developing therapies for treatment of congenital hyperinsulinism (CHI). The company operate in Ireland, the US, the UK, the Netherland, Germany, France, Spain, Japan, Canada and Italy. Rhythm Pharmaceuticals is headquartered in Boston, Massachusetts, the US.

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Headquarters United States of America

Address 222 Berkeley Street, 12th Floor, Boston, Massachusetts, 02116


Telephone 1 857 2644280

No of Employees 414

Industry Pharmaceuticals and Healthcare

Ticker Symbol & Exchange RYTM (NASD)

Revenue (2024) $189.8M 45.8% (2024 vs 2023)

EPS XYZ

Net Income (2024) XYZ 24.6% (2024 vs 2023)

Market Cap* $7.6B

Net Profit Margin (2024) XYZ 48.3% (2024 vs 2023)

* As of and is in US$
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Rhythm Pharmaceuticals Inc premium industry data and analytics

100+

Lead Sheet

Understand when and why to target accounts of prospective leads, as well as who to reach out to, drawing on intelligence for Rhythm Pharmaceuticals Inc’s relevant decision makers and contact details.

70+

Catalyst Calendar

Proactively evaluate Rhythm Pharmaceuticals Inc’s catalyst impacts to stay ahead of the competition & improve corporate planning. Bolster business development with timely opportunities.

20+

Clinical Trials

Determine Rhythm Pharmaceuticals Inc go-to-market proposition and gain insight into the company’s clinical operations, recruitment, and trial strategy.

5

Pipeline Drugs

Identify which of Rhythm Pharmaceuticals Inc’s products will be commercialized, helping you to better contend with shifting product portfolios, and allowing you to stay one step ahead of the market.

3

Regulatory Milestones

Track drug and patent expiries along with geographies impacted.

3

Insights

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1

Marketed Drugs

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Products and Services

Products Brands
Pipeline IMCIVREE
IMCIVREE (Setmelanotide): Chronic Weight Management, Hyperphagia and Severe Obesity Rhythm
Severe Obesity
XYZ
XYZ
XYZ
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History

History section provides information on new products, mergers, acquisitions, expansions, approvals, and many more key events.

Year Event Description
2025 Contracts/Agreements In November, the company signed a Product Registration Agreement with Non-Insured Health Benefits for public reimbursement of IMCIVREE for weight management in eligible adult and pediatric patients.
2025 Others In March, the company reacquired the rights to IMCIVREE (setmelanotide) in China, including mainland China, Hong Kong and Macau.
2025 Contracts/Agreements In March, the company partnered with the Raymond A. Wood Foundation to study the impact of fatigue on persons with craniopharyngioma.
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Competitor Comparison

Key Parameters Rhythm Pharmaceuticals Inc Alnylam Pharmaceuticals Inc BridgeBio Pharma Inc Crinetics Pharmaceuticals Inc BlueWillow Biologics Inc
Headquarters United States of America United States of America United States of America United States of America United States of America
City Boston Cambridge Palo Alto San Diego Ann Arbor
State/Province Massachusetts Massachusetts California California Michigan
No. of Employees 414 2,500 834 594 -
Entity Type Public Public Public Public Private
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Executives
Name Position Board Since Age
David P. Meeker, M.D Chairman; Chief Executive Officer; President Executive Board 2020 71
Hunter C. Smith Chief Financial Officer Senior Management 2017 58
Alastair Garfield Chief Scientific Officer Senior Management 2024 46
Jennifer Lee Head - North America; Executive Vice President Senior Management 2020 51
Jim Flaherty General Counsel; Senior Vice President Senior Management 2019 -
Non Dignissim Eros Proin vel Convallis 2026 XY
Non Dignissim Eros Proin vel Convallis 2026 XY
Non Dignissim Eros Proin vel Convallis 2026 XY
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