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Silence Therapeutics Plc: Overview

Silence Therapeutics plc (Silence Therapeutics) is a developer of therapeutics that channels gene silencing to cure life-threatening diseases. The company's pipeline products include SLN124 and SLN360. Its SLN360 is developed for the treatment of cardiovascular disease with high Lp(a) in risk of heart disease and heart stroke, and SLN124 for e-Thalassaemia and myelodysplastic syndrome. Silence Therapeutics also provides RNA interfaces that include short interfering RNA (siRNA) and messenger RNAs (mRNA). The company collaborates with pharmaceutical, biotechnology companies and academic research institutions. It operates in Germany, the US and the UK. Silence Therapeutics is headquartered in London, England, the UK.

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Headquarters United Kingdom

Address 72 Hammersmith Road, London, England, W148TH


Telephone 44 20 34576900

No of Employees 116

Industry Pharmaceuticals and Healthcare

Ticker Symbol & Exchange SLNCF (OTC)

Revenue (2021) $21.6M 41% (2021 vs 2020)

EPS XYZ

Net Income (2021) XYZ -2.7% (2021 vs 2020)

Market Cap* $1.0B

Net Profit Margin (2021) XYZ 27.1% (2021 vs 2020)

* As of and is in US$
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Silence Therapeutics Plc premium industry data and analytics

40+

Lead Sheet

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30+

Pipeline Drugs

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20+

Catalyst Calendar

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20+

Clinical Trials

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2

Regulatory Milestones

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1

Insights

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1

ICT Spend & Tech Priorities

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Products and Services

Products
Pipeline
SLN360 – For Cardiovascular Disease
SLN124 - For e-Thalassaemia and Myelodysplastic Syndrome
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Competitor Comparison

Key Parameters Silence Therapeutics Plc Novartis Pharmaceuticals UK Ltd Oxford BioMedica Plc Alnylam UK Ltd Blueberry Therapeutics Ltd
Headquarters United Kingdom United Kingdom United Kingdom United Kingdom United Kingdom
City London London Oxford Maidenhead Alderley Edge
State/Province England England England Berkshire Cheshire
No. of Employees 116 869 891 - -
Entity Type Public Private Public Private Private
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Executives
Name Position Board Since Age
Iain Gladstone Ross Chairman Executive Board 2019 69
Craig Tooman Chief Executive Officer; President; Director Executive Board 2022 58
Giles Victor Campion Head-Research and Development; Chief Medical Officer; Director; Executive Vice President Executive Board 2020 69
Rhonda Hellums Chief Financial Officer Senior Management 2022 51
Curtis Rambaran, MD Chief Medical Officer Senior Management 2023 -
Non Dignissim Eros Proin vel Convallis 2024 XY
Non Dignissim Eros Proin vel Convallis 2024 XY
Non Dignissim Eros Proin vel Convallis 2024 XY
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