Simulations Plus Inc - Company Profile
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Business Description
Simulations Plus Inc (Simulations Plus) offers advanced software and consulting services that optimize drug discovery, development, clinical trials, regulatory submissions, and commercialization.
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R&D Overview
Simulations Plus focuses its research and development efforts on enhancing existing products and developing new software solutions, with a particular emphasis on integrating artificial intelligence (AI) and cloud computing to expand its product portfolio. The company capitalizes software development costs once technological feasibility is established, with these costs primarily composed of salaries and direct payroll-related expenses. The R&D teams operate remotely, leveraging collaboration tools to design and develop products, which are delivered electronically. Additionally, Simulations Plus protects its intellectual property through trademarks, copyrights, trade secrets, and contractual measures, and strategically acquires technologies, such as the DILIsym technology for drug-induced liver disease and the Lixoft scientific software, to complement its internal development efforts. In FY2025, the company invested US$6.9 million in its R&D activities and as a percentage of its revenue stood at 8.7%.
Business Segments
Overview
Focuses on areas such as population pharmacokinetics and pharmacodynamics (PKPD), quantitative systems pharmacology (QSP), and physiologically-based pharmacokinetic (PBPK) modeling. These services provide critical expertise in clinical trial design, dose selection, safety and efficacy analysis, and regulatory submissions. Its consulting expertise also extends to early drug discovery, where it provides in silico drug design and optimization, high-throughput screening, and structure-activity relationship modeling. Offers specialized services in adaptive learning solutions and medical communications. Its adaptive learning programs deliver engaging, data-driven content for training on complex procedures, while its medical communications services support marketplace insights and clinical development efforts.
Performance
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Overview
Provides software solutions for the pharmaceutical industry, specializing in research, development, and commercialization. It offers a diverse range of products that leverage advanced simulation and modeling techniques to enhance drug discovery and development processes. Offers three simulation products designed to provide time-dependent results by solving large sets of mechanistic differential equations: GastroPlus, DDDPlus, and MembranePlus. These are widely used in the industry to simulate absorption, drug interactions, and compound behavior in humans and animals. Offers two AI and machine learning-based tools: ADMET Predictor and MedChem Designer. These predict and analyze the static properties of chemicals and assist in determining molecular properties, helping chemists evaluate the likelihood of success for various compounds in a company’s chemical library. Offers seven mechanistic, mathematical modeling tools: DILIsym, NAFLDsym, ILDsym, IPFsym, RENAsym, MITOsym, and OBESITYsym. These products are focused on specific areas of drug development, such as liver toxicity, metabolic diseases, and obesity, and are used to simulate biological processes in the human body. Offers MonolixSuite, a comprehensive platform used for population analyses, clinical trial simulations, and regulatory submissions. It integrates several tools, including Monolix, PKanalix, and Simulx, and is widely utilized in clinical drug development across all stages. Also provides Pro-ficiency Performance Management, a product designed for education and compliance training, and Panorama KOL Insights, which supports key opinion leader research in the medical community.
Performance
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Geographical Segments
Performance
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Performance
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Performance
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