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Spruce Biosciences Inc: Overview

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Spruce Biosciences Inc (Spruce Biosciences) is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders. The company pipeline products including Tralesinidase Alfa (TA-ERT) for the treatment of mucopolysaccharidosis type IIIB (sanfilippo syndrome type B); and SPR202 which treats congenital adrenal hyperplasia (CAH).Spruce Biosciences focuses on reducing the hyperresponsiveness of adrenocorticotropic hormone (ACTH), a hormone involved in the production of cortisol and improve disease control and glucocorticoid steroid burden. The company offers services such as medical services, healthcare services, clinical trials, among others. Spruce Biosciences is headquartered in South San Francisco, California, the US.

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Headquarters United States of America

Address 611 Gateway Boulevard, Suite 740, South San Francisco, California, 94080


No of Employees 14

Industry Pharmaceuticals and Healthcare

Ticker Symbol & Exchange SPRB (NASD)

EPS XYZ

Net Income (2024) XYZ 26.5% (2024 vs 2023)

Market Cap* $121.9M

Net Profit Margin (2023) XYZ -127.4% (2024 vs 2023)

   

   

* As of and is in US$
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Spruce Biosciences Inc premium industry data and analytics

20+

Catalyst Calendar

Proactively evaluate Spruce Biosciences Inc’s catalyst impacts to stay ahead of the competition & improve corporate planning. Bolster business development with timely opportunities.

10+

Clinical Trials

Determine Spruce Biosciences Inc go-to-market proposition and gain insight into the company’s clinical operations, recruitment, and trial strategy.

1

Regulatory Milestones

Track drug and patent expiries along with geographies impacted.

1

Pipeline Drugs

Identify which of Spruce Biosciences Inc’s products will be commercialized, helping you to better contend with shifting product portfolios, and allowing you to stay one step ahead of the market.

1

Insights

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Products and Services

Products
Pipeline
Tralesinidase Alfa (TA-ERT): Mucopolysaccharidosis Type IIIB (Sanfilippo Syndrome Type B) SPR202: Congenital Adrenal Hyperplasia (CAH)
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History

History section provides information on new products, mergers, acquisitions, expansions, approvals, and many more key events.

Year Event Description
2025 Asset Purchase In April, the company acquired tralesinidase alfa (TA-ERT) from BioMarin.
2024 Contracts/Agreements In October, the company signed an agreement to purchase certain assets—including intellectual property, inventory, and contracts—linked to particular pharmaceutical products from AVX (ABC) LLC for US$5 million.
2023 Contracts/Agreements In January, the company entered into a licensing agreement with Kaken Pharmaceutical Co. Ltd for the development and commercialization of Spruce’s product candidate, tildacerfont, for the treatment of congenial adrenal hyperplasia in Japan.
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Competitor Comparison

Key Parameters Spruce Biosciences Inc Crinetics Pharmaceuticals Inc Lipocine Inc Tempest Therapeutics Inc
Headquarters United States of America United States of America United States of America United States of America
City South San Francisco San Diego Salt Lake Brisbane
State/Province California California Utah California
No. of Employees 14 594 14 4
Entity Type Public Public Public Public
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Executives
Name Position Board Since Age
Michael Grey Chairman Executive Board 2017 73
Javier Szwarcberg, M.D Chief Executive Officer; Director Executive Board 2022 56
Kirk Ways, M.D., Ph.D Chief Medical Officer - Interim; Director Executive Board 2021 74
Samir Gharib Chief Financial Officer; President Senior Management 2022 43
Corwin Dale Hooks Chief Commercial Officer Senior Management 2026 59
Non Dignissim Eros Proin vel Convallis 2026 XY
Non Dignissim Eros Proin vel Convallis 2026 XY
Non Dignissim Eros Proin vel Convallis 2026 XY
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