Cardiff Oncology Inc - Company Profile
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Cardiff Oncology Inc (Cardiff) is a clinical-stage biotechnology company focused on developing novel cancer therapies. The company's main activity involves leveraging PLK1 inhibition to create treatments for various cancers with significant unmet medical needs. Its major product is onvansertib, an oral and highly selective PLK1 inhibitor, which is being developed in combination with standard-of-care therapeutics. Cardiff is advancing various clinical trials, including the Phase 2 CRDF-004 trial for first-line RAS-mutated metastatic colorectal cancer (mCRC) and the TROV-054 trial for second-line KRAS-mutated mCRC. The company utilizes tumor genomics and biomarker assays to enhance patient response assessments. It is also investigating onvansertib for metastatic pancreatic ductal adenocarcinoma, small cell lung cancer, and triple-negative breast cancer, exploring various combination therapies. Cardiff is headquartered in San Diego, California, the US.
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