Crescent Biopharma Inc - Company Profile

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Crescent Biopharma Inc: Overview

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Crescent Biopharma Inc (Crescent Biopharma), formerly GlycoMimetics Inc, is a clinical-stage biotechnology company focused on developing transformative therapies for cancer treatment. The company's main activities involve the identification and development of innovative oncology therapeutics. Crescent Biopharma's major product in development is CR-001, a PD-1 x VEGF bispecific antibody designed to target both the PD-1 immune checkpoint and Vascular Endothelial Growth Factor. The company is also building a portfolio of potentially best-in-class antibody-drug conjugates (ADCs). Crescent Biopharma's products are aimed at treating solid tumors, with applications in the healthcare industry. The company is in the early stage of development and commercialization SKB105 (CR-003). Crescent Biopharma is headquartered in Waltham, Massachusetts, the US.

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Headquarters United States of America

Address 300 Fifth Avenue, Waltham, Massachusetts, 02451


Telephone 1 617 4305595

No of Employees 44

Industry Pharmaceuticals and Healthcare

Ticker Symbol & Exchange CBIO (NASD)

Revenue (2024) $10.8M

EPS XYZ

Net Income (2024) XYZ -311.7% (2024 vs 2023)

Market Cap* $643.7M

Net Profit Margin (2024) XYZ 97.7% (2024 vs 2023)

* As of and is in US$
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Crescent Biopharma Inc premium industry data and analytics

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Clinical Trials

Determine Crescent Biopharma Inc go-to-market proposition and gain insight into the company’s clinical operations, recruitment, and trial strategy.

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Catalyst Calendar

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Pipeline Drugs

Identify which of Crescent Biopharma Inc’s products will be commercialized, helping you to better contend with shifting product portfolios, and allowing you to stay one step ahead of the market.

9

Insights

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Regulatory Milestones

Track drug and patent expiries along with geographies impacted.

Products and Services

Products
Pipeline
CR-001: PD-1 and VEGF in solid tumors
CR-002: PD-L1 in cancer cells
XYZ
XYZ
XYZ
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History

History section provides information on new products, mergers, acquisitions, expansions, approvals, and many more key events.

Year Event Description
2025 Contracts/Agreements In December, the company entered into a License Agreement with Sichuan Kelun-Biotech Biopharmaceutical Co Ltd, to research, develop, manufacture, and commercialize CR-001 in Greater China.
2025 Acquisitions/Mergers/Takeovers In June, the company merged with Crescent Biopharma, a biotech company and renamed itself as Crescent Biopharma Inc.
2021 Regulatory Approval In January, the company’s APL-106 (uproleselan) has been granted Breakthrough Therapy Designation from the China National Medical Products Administration Center for Drug Evaluation for the treatment of acute myeloid leukemia.
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Competitor Comparison

Key Parameters Crescent Biopharma Inc BioNTech SE ImmunityBio Inc Kura Oncology Inc Instil Bio Inc
Headquarters United States of America Germany United States of America United States of America United States of America
City Waltham Mainz San Diego San Diego Dallas
State/Province Massachusetts Rheinland-Pfalz California California Texas
No. of Employees 44 7,807 691 260 17
Entity Type Public Public Public Public Public
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Executives
Name Position Board Since Age
Joshua Brumm Director; Chief Executive Officer Executive Board 2025 48
Richard Scalzo Chief Financial Officer Senior Management 2025 39
Jonathan McNeill Chief Operating Officer; President Senior Management 2025 40
Ellie Im Chief Medical Officer Senior Management 2025 48
Jan Pinkas Chief Scientific Officer Senior Management 2025 57
Non Dignissim Eros Proin vel Convallis 2026 XY
Non Dignissim Eros Proin vel Convallis 2026 XY
Non Dignissim Eros Proin vel Convallis 2026 XY
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