MetaVia Inc - Company Profile

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Business Description

MetaVia Inc (MetaVia ), a subsidiary of Dong-A ST Co Ltd, develops and commercializes pharmaceuticals targeting cardiometabolic diseases. The company focuses on creating innovative therapies for conditions such as metabolic dysfunction-associated steatohepatitis (MASH) and obesity. MetaVia's key programs include DA-1241, a G-Protein-Coupled Receptor 119 agonist, and DA-1726, an oxyntomodulin analogue. The company operates within the biotechnology and pharmaceutical industries, concentrating on research and development activities, preclinical developments, and clinical trials.

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R&D Overview

MetaVia’s R&D initiatives focus on developing innovative therapies for cardiometabolic diseases. The company is advancing two key assets: DA-1241, a GPR119 agonist in Phase 2a trials for the treatment of metabolic dysfunction-associated steatohepatitis (MASH), and DA-1726, a GLP-1 receptor and glucagon receptor dual agonist in Phase 1 trials for obesity. DA-1241 has shown potential in reducing hepatic steatosis, inflammation, and fibrosis, while DA-1726 aims to induce weight loss and improve body composition. MetaVia Inc is also exploring the efficacy of DA-1241 in combination with sitagliptin, a DPP-4 inhibitor, to enhance therapeutic outcomes. Its R&D unit is responsible for managing the company's research and development activities, including preclinical developments, clinical trials, and the advancement of product candidates through various phases of clinical development. The unit focuses on identifying, recruiting, retaining, and integrating qualified scientific personnel to support these initiatives. In FY2024, the company invested US$21.5 million, which grew 135.4% YoY.

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