Vertex Pharmaceuticals Inc - Company Profile

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Vertex Pharmaceuticals Inc: Overview

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Vertex Pharmaceuticals Inc (Vertex) is a biotechnology company that discovers, develops, and manufactures transformative medicines for serious diseases. Vertex's major products include therapies for cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia, and acute pain. The company's products are distributed through local and international pharmacies, hospitals, clinics, specialty distributors to patients, health care providers, and authorized treatment centers. Vertex offers its products in the Americas, Europe, Asia, and the Middle East, through the brands Alyftrek, Casgevy, Kaftrio, Orkambi, and Trikafta, among others. It operates manufacturing facilities in the US and collaborates to manufacture its products. Vertex is headquartered in Boston, Massachusetts, the US.

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Headquarters United States of America

Address 50 Northern Avenue, Boston, Massachusetts, 02210


Telephone 1 617 3416100

No of Employees 6,400

Industry Pharmaceuticals and Healthcare

Ticker Symbol & Exchange VRTX (NASD)

Revenue (2025) $12.0B 8.9% (2025 vs 2024)

EPS XYZ

Net Income (2025) XYZ 838.1% (2025 vs 2024)

Market Cap* $112.6B

Net Profit Margin (2025) XYZ 777.8% (2025 vs 2024)

* As of and is in US$
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Vertex Pharmaceuticals Inc premium industry data and analytics

340+

Clinical Trials

Determine Vertex Pharmaceuticals Inc go-to-market proposition and gain insight into the company’s clinical operations, recruitment, and trial strategy.

210+

Lead Sheet

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180+

Catalyst Calendar

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130+

Pipeline Drugs

Identify which of Vertex Pharmaceuticals Inc’s products will be commercialized, helping you to better contend with shifting product portfolios, and allowing you to stay one step ahead of the market.

100+

Insights

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17+

Regulatory Milestones

Track drug and patent expiries along with geographies impacted.

10+

Sales & Consensus Forecasts

Understand the current and future drug revenue for Vertex Pharmaceuticals Inc and assess market opportunity for new entrants with patient population 8-year forecasts.

5

Marketed Drugs

Understand Vertex Pharmaceuticals Inc’s commercialized product portfolio to stay one step ahead of the market.

1

Investigators

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1

ICT Spend & Tech Priorities

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Products and Services

Products Brands
Medicine for Cystic Fibrosis Vertex
Medicine for Sickle Cell Disease and Transfusion-Dependent Beta Thalassemia Kalydeco
Medicine for Acute Pain Orkambi
XYZ XYZ
XYZ XYZ
XYZ XYZ
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History

History section provides information on new products, mergers, acquisitions, expansions, approvals, and many more key events.

Year Event Description
2025 Acquisitions/Mergers/Takeovers In September, the company signed a reimbursement agreement with the Italian Medicines Agency (AIFA) for eligible transfusion-dependent beta thalassemia and severe sickle cell disease (SCD) patients.
2025 Regulatory Approval In April, the company received approval from the European Commission to use KAFTRIO in combination with ivacaftor for people with cystic fibrosis.
2025 Regulatory Approval In March, the company received regulatory approval from the UK MHRA for ALYFTREK (deutivacaftor/tezacaftor/vanzacaftor) to treat cystic fibrosis.
Dive into past operations, including product releases, deals, acquisitions & more Dive into past operations, including product releases, deals, acquisitions & more Learn more
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Competitor Comparison

Key Parameters Vertex Pharmaceuticals Inc Eli Lilly and Co Merck & Co Inc AstraZeneca Plc AbbVie Inc
Headquarters United States of America United States of America United States of America United Kingdom United States of America
City Boston Indianapolis Rahway Cambridge North Chicago
State/Province Massachusetts Indiana New Jersey Cambridgeshire Illinois
No. of Employees 6,400 47,000 73,000 96,100 55,000
Entity Type Public Public Public Public Public
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Executives
Name Position Board Since Age
Jeffrey Leiden, MD, PhD Chairman Executive Board 2020 69
Reshma Kewalramani, MD Chief Executive Officer; President; Director Executive Board 2020 52
Charles F. Wagner, Jr. Chief Financial Officer; Executive Vice President Senior Management 2019 56
Stuart A. Arbuckle Executive Vice President; Chief Operating Officer Senior Management 2021 59
Kristen C. Ambrose Senior Vice President; Chief Accounting Officer Senior Management 2021 48
Non Dignissim Eros Proin vel Convallis 2026 XY
Non Dignissim Eros Proin vel Convallis 2026 XY
Non Dignissim Eros Proin vel Convallis 2026 XY
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