Aptose Biosciences Inc - Company Profile
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Aptose Biosciences Inc (Aptose) is a clinical-stage biotechnology company. It develops innovative medicines to address unmet clinical needs in oncology, with a focus on hematology. The company’s product pipeline includes two oral kinase inhibitors: tuspetinib (HM43239) and luxeptinib (CG-806). Tuspetinib is being evaluated for frontline therapy in newly diagnosed acute myeloid leukemia (AML) and has demonstrated complete responses in relapsed or refractory AML patients. It is also being explored in combination with venetoclax. Luxeptinib targets kinases in myeloid and lymphoid malignancies and has shown tumor shrinkage in trials for relapsed B-cell leukemias. Aptose operates primarily in the biotechnology and pharmaceutical industries, serving healthcare providers and patients in need of advanced cancer treatments. Aptose is headquartered in Toronto, Ontario, Canada.
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Products and Services
| Products |
|---|
| Pipeline: |
| Tuspetinib: Myeloid Tumors |
| Luxeptinib: B-cell and Myeloid Tumors |
History
History section provides information on new products, mergers, acquisitions, expansions, approvals, and many more key events.
| Year | Event | Description |
|---|---|---|
| 2026 | Ownership Changes | In June, the company was acquired by Hanmi Pharmaceutical Co Ltd, a biotechnology company. |
| 2024 | Contracts/Agreements | In August, the company secured a US$10 million loan from Hanmi Pharmaceutical Co Ltd and began negotiations for a new co-development agreement to accelerate tuspetinib's clinical development. |
| 2023 | Contracts/Agreements | In May, the company entered a US$25 common share purchase agreement and registration rights agreement with an institutional investor. |
Competitor Comparison
| Key Parameters | Aptose Biosciences Inc | AbbVie Inc | Jazz Pharmaceuticals Plc | Rigel Pharmaceuticals Inc | Syndax Pharmaceuticals Inc |
|---|---|---|---|---|---|
| Headquarters | Canada | United States of America | Ireland | United States of America | United States of America |
| City | Toronto | North Chicago | Dublin | South San Francisco | New York City |
| State/Province | Ontario | Illinois | Dublin | California | New York |
| No. of Employees | 14 | 57,000 | 2,890 | 172 | 298 |
| Entity Type | Public | Public | Public | Public | Public |
Key Financial Charts
Sales Growth
Net Income Growth
Executives
| Name | Position | Board | Since | Age |
|---|---|---|---|---|
| William G. Rice, Ph.D. | President; Chief Executive Officer; Chairman | Executive Board | 2013 | 67 |
| Fletcher Payne | Chief Business Officer; Chief Financial Officer; Senior Vice President | Senior Management | 2022 | 63 |
| Rafael Bejar, M.D., Ph.D. | Senior Vice President; Chief Medical Officer | Senior Management | 2020 | 55 |
| Robert B. Killion Jr., Ph.D. | Vice President - CMC | Senior Management | - | - |
| Marc Wiles, Ph.D. | Senior Vice President - Regulatory Affairs | Senior Management | - | - |
| Non Dignissim Eros | Proin vel | Convallis | 2026 | XY |
| Non Dignissim Eros | Proin vel | Convallis | 2026 | XY |
| Non Dignissim Eros | Proin vel | Convallis | 2026 | XY |
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